214 Result(s)

Article

Characterization of the promoter region of the bovine long-chain acyl-CoA synthetase 1 gene: Roles of E2F1, Sp1, KLF15 and E2F4

The nutritional value and eating qualities of beef are enhanced when the unsaturated fatty acid content of fat is increased. Long-chain acyl-CoA synthetase 1 (ACSL1) plays key roles in fatty acid transport and...

Zhi-Dong Zhao, Lin-Sen Zan, An-Ning Li, Gong Cheng, Shi-Jun Li… in Scientific Reports (2016)

Article

Therapeutic efficacy of apelin on transplanted mesenchymal stem cells in hindlimb ischemic mice via regulation of autophagy

Mesenchymal stem cells (MSCs)-based therapy provides a promising avenue for the management of peripheral arterial disease (PAD). However, engrafted MSCs are subjected to acute cell death in the ischemic microe...

Dong Liang, Dong Han, Weiwei Fan, Ran Zhang, Hongyu Qiao… in Scientific Reports (2016)

Article

XXIV World Allergy Congress 2015

A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts

Heung-Man Lee, Il-Ho Park, Jae-Min Shin… in World Allergy Organization Journal (2016)

Article

SP1 and UTE1 Decoy ODNs inhibit activation and proliferation of hepatic stellate cells by targeting tissue inhibitors of metalloproteinase 1

The excessive accumulation of extracellular matrix of hepatic fibrosis is positively correlated with tissue inhibitors of metalloproteinase 1 (TIMP1). Here we aimed to investigate whether TIMP1 may be down-reg...

Dong Jia, Yi-Ran Ni, Yan-Qiong Zhang, Chun Rao, Jun Hou, He-Qing Tang… in Cell & Bioscience (2016)

Article

A critical time window for the analgesic effect of central histamine in the partial sciatic ligation model of neuropathic pain

It is known that histamine participates in pain modulation. However, the effect of central histamine on neuropathic pain is not fully understood. Here, we report a critical time window for the analgesic effect...

Jie Yu, Ying-Ying Tang, Ran-Ran Wang, Guo-Dong Lou… in Journal of Neuroinflammation (2016)

Article

A novel mutant allele of SSI2 confers a better balance between disease resistance and plant growth inhibition on Arabidopsis thaliana

Resistance and growth are opposing characteristics in plants. SA INSENSITIVITY OF npr1-5 (SSI2) encodes a stearoyl-ACP desaturase (S-ACP DES) that has previously been reported to simultaneously enhance resistance...

Wei Yang, Ran Dong, Li Liu, Zhubing Hu, **g Li, Yong Wang… in BMC Plant Biology (2016)

Article

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two

Casey Ager, Matthew Reilley, Courtney Nicholas… in Journal for ImmunoTherapy of Cancer (2016)

Article

Thioredoxin-interacting protein regulates haematopoietic stem cell ageing and rejuvenation by inhibiting p38 kinase activity

Ageing is a natural process in living organisms throughout their lifetime, and most elderly people suffer from ageing-associated diseases. One suggested way to tackle such diseases is to rejuvenate stem cells,...

Haiyoung Jung, Dong Oh Kim, Jae-Eun Byun, Won Sam Kim… in Nature Communications (2016)

Article

Suppressor of Cytokine Signaling 2 Negatively Regulates NK Cell Differentiation by Inhibiting JAK2 Activity

Suppressor of cytokine signaling (SOCS) proteins are negative regulators of cytokine responses. Although recent reports have shown regulatory roles for SOCS proteins in innate and adaptive immunity, their role...

Won Sam Kim, Mi Jeong Kim, Dong Oh Kim, Jae-Eun Byun, Hangsak Huy… in Scientific Reports (2017)

Article

WAO International Scientific Conference (WISC 2016) Abstracts

Jun Bao, Yi-Hui Wang, Quan-Hua Liu, Yi-**ao Bao… in World Allergy Organization Journal (2017)

Article

Autophagy and multidrug resistance in cancer

Multidrug resistance (MDR) occurs frequently after long-term chemotherapy, resulting in refractory cancer and tumor recurrence. Therefore, combatting MDR is an important issue. Autophagy, a self-degradative sy...

Ying-Jie Li, Yu-He Lei, Nan Yao, Chen-Ran Wang, Nan Hu… in Chinese Journal of Cancer (2017)

Article

A TBX5 3′UTR variant increases the risk of congenital heart disease in the Han Chinese population

TBX5 is a vital transcription factor involved in cardiac development in a dosage-dependent manner. But little is known about the potential association of TBX5 3′ untranslated region (UTR) variations with congenit...

Feng Wang, Dong Liu, Ran-Ran Zhang, Li-Wei Yu, Jian-Yuan Zhao… in Cell Discovery (2017)

Article

Complete mitochondrial genomes of Anopheles stephensi and An. dirus and comparative evolutionary mitochondriomics of 50 mosquitoes

To better understand the phylogeny and evolution of mosquitoes, the complete mitochondrial genome (mitogenome) of Anopheles stephensi and An. dirus were sequenced and annotated, and a total of 50 mosquito mitogen...

You-** Hao, Yi-Lin Zou, Yi-Ran Ding, Wen-Yue Xu, Zhen-Tian Yan… in Scientific Reports (2017)

Article

Conformational determinants necessary for secretion of Paecilomyces thermophila β-1,4-xylosidase that lacks a signal peptide

In this study, we investigated the secretion mechanism of the hyper-secretion signal peptide-lacking β-xylosidase PtXyl43, a non-classically secreted protein, from the fungus Paecilomyces thermophila in Escherich...

Yalin Yang, Juan Li, Qiang Yu, Junxiu Hou, Chenchen Gao, Dong Li, Yang Liu… in AMB Express (2018)

Article

PEST-containing nuclear protein mediates the proliferation, migration, and invasion of human neuroblastoma cells through MAPK and PI3K/AKT/mTOR signaling pathways

PEST-containing nuclear protein (PCNP), a novel nuclear protein, is involved in cell proliferation and tumorigenesis. However, the precise mechanism of action of PCNP in the process of tumor growth has not yet...

Dong-Dong Wu, Ying-Ran Gao, Tao Li, Da-Yong Wang, Dan Lu, Shi-Yu Liu, Ya Hong… in BMC Cancer (2018)

Article

Clinical performance of stem cell therapy in patients with acute-on-chronic liver failure: a systematic review and meta-analysis

Stem cell therapy has been applied in the treatment of acute-on-chronic liver failure (ACLF). However, its clinical efficiency is still debatable. The aim of this systematic review and meta-analysis is to eval...

Ran Xue, Qinghua Meng, **ling Dong, Juan Li… in Journal of Translational Medicine (2018)

Article

Chinese guidelines for the diagnosis and treatment of hand, foot and mouth disease (2018 edition)

Hand, foot, and mouth disease (HFMD) is a common infectious disease in childhood caused by an enterovirus (EV), and which is principally seen in children under 5 years of age. To promote diagnostic awareness a...

**ng-Wang Li, **n Ni, Su-Yun Qian, Quan Wang… in World Journal of Pediatrics (2018)

Article

Flavonoids are identified from the extract of Scutellariae Radix to suppress inflammatory-induced angiogenic responses in cultured RAW 264.7 macrophages

Scutellariae Radix (SR), also named Huangqin in China, is the dried root of Scutellaria baicalensis Georgi. Historically, the usage of SR was targeted to against inflammation. In fact, chronic inflammation has a ...

Guowei Gong, Huaiyou Wang, **angpeng Kong, Ran Duan, Tina T. X. Dong… in Scientific Reports (2018)

Chapter and Conference Paper

The Sixth Visual Object Tracking VOT2018 Challenge Results

The Visual Object Tracking challenge VOT2018 is the sixth annual tracker benchmarking activity organized by the VOT initiative. Results of over eighty trackers are presented; many are state-of-the-art trackers...

Matej Kristan, Aleš Leonardis, Jiří Matas… in Computer Vision – ECCV 2018 Workshops (2019)

Article

Sedimentary environment controls on the accumulation of organic matter in the Upper Ordovician Wufeng–Lower Silurian Longmaxi mudstones in the Southeastern Sichuan Basin of China

The Upper Ordovician–Lower Silurian mudstones (including the Wufeng, Guanyinqiao and Longmaxi Formations) in the Sichuan Basin are some of the most important shale gas plays in China. In order to enhance our u...

Lei Yang, Bo Ran, Yu-Yue Han, Shu-Gen Liu, Yue-Hao Ye… in Petroleum Science (2019)