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  1. Article

    Open Access

    Angiotensin Receptor Blockers and the Risk of Suspected Drug-Induced Liver Injury: A Retrospective Cohort Study Using Electronic Health Record-Based Common Data Model in South Korea

    Angiotensin receptor blockers are widely used antihypertensive drugs in South Korea. In 2021, the Korea Ministry of Food and Drug Safety acknowledged the need for national compensation for a drug-induced liver...

    Hyunjoo Kim, Nayeong Son, Dahee Jeong, Myungsik Yoo, In Young Choi in Drug Safety (2024)

  2. No Access

    Article

    Multi-omics portrait of ductal carcinoma in situ in young women

    Young patients with breast ductal carcinoma in situ (DCIS) often face a poorer prognosis. The genomic intricacies in young-onset DCIS, however, remain underexplored.

    Ruoxi Hong, Boyang Cao, Dongshao Chen, Wei Wu in Breast Cancer Research and Treatment (2024)

  3. Article

    Open Access

    A Beginner’s Guide to Artificial Intelligence for Ophthalmologists

    The integration of artificial intelligence (AI) in ophthalmology has promoted the development of the discipline, offering opportunities for enhancing diagnostic accuracy, patient care, and treatment outcomes. ...

    Daohuan Kang, Hongkang Wu, Lu Yuan, Yu Shi, Kai ** in Ophthalmology and Therapy (2024)

  4. No Access

    Article

    Comparison between a tubeless, on-body automated insulin delivery system and a tubeless, on-body sensor-augmented pump in type 1 diabetes: a multicentre randomised controlled trial

    This study compares the efficacy and safety of a tubeless, on-body automated insulin delivery (AID) system with that of a tubeless, on-body sensor-augmented pump (SAP).

    Ji Yoon Kim, Sang-Man **, Eun Seok Kang, Soo Heon Kwak, Yeoree Yang in Diabetologia (2024)

  5. No Access

    Article

    Effects of Acupotomy on Immobilization-Induced Gastrocnemius Contracture and Fibrosis in Rats via Wnt/β-Catenin Signaling

    To determine whether acupotomy ameliorates immobilization-induced muscle contracture and fibrosis via Wnt/β-catenin signaling pathway.

    Rui Hu, Jun-kang Pan, Jia-hui Li, Han Zhang in Chinese Journal of Integrative Medicine (2024)

  6. Article

    Open Access

    Preoperative evaluation of mediastinal lymph nodes in non-small cell lung cancer using [68Ga]FAPI-46 PET/CT: a prospective pilot study

    Mediastinal nodal staging is crucial for surgical candidate selection in non-small cell lung cancer (NSCLC), but conventional imaging has limitations often necessitating invasive staging. We investigated the a...

    Yeon-koo Kang, Kwon Joong Na, Jimyung Park in European Journal of Nuclear Medicine and M… (2024)

  7. No Access

    Article

    Graves’ orbitopathy development in thyroid cancer patients: a 16-year nationwide cohort study in South Korea

    We aimed to investigate the prevalence, risk factors, and prognosis of Graves’ orbitopathy (GO) in patients with thyroid cancer without a history of hyperthyroidism.

    Minjeong Kim, Jooyoung Lee, Yu Been Hwang, **mo Kang, Hwa Young Ahn, Jeong Kyu Lee in Eye (2024)

  8. Article

    Open Access

    Azithromycin sequential therapy plus inhaled terbutaline for Mycoplasma Pneumoniae pneumonia in children: a systematic review and meta-analysis

    An improper host immune response to Mycoplasma pneumoniae generates excessive inflammation, which leads to the impairment of pulmonary ventilation function (PVF). Azithromycin plus inhaled terbutaline has been us...

    Yongcheng Sheng, Yi Liang, Chongyang Zhao, Deying Kang in BMC Infectious Diseases (2024)

  9. Article

    Open Access

    Real-world evidence of a novel tetravalent immunoglobulin Y effectiveness and safety in patients with the refractory Helicobacter pylori infection

    Refractory Helicobacter pylori (H. pylori) infection inevitably increase the difficulty of drug selection. Here, we described our experience with the use of a novel tetravalent IgY against H. pylori for the treat...

    Nan Hao, Bo Liu, Meng Zhao, Mingming Lu, Feiyi Chen, Jialu Kang in BMC Infectious Diseases (2024)

  10. No Access

    Article

    The role of intraoperative central lymph node biopsy in the treatment of clinically low-risk PTMC

    To evaluate the role of intraoperative frozen biopsy of central lymph nodes in central neck dissection and thyroidectomy in patients of unilateral, clinically negative nodes (cN0) papillary thyroid microcarcin...

    Wei Cai, Yajun Wang, **g Zhao, Kaifu Li, Ye Zhao, Hua Kang in Endocrine (2024)

  11. Article

    Open Access

    Expression and significance of Fractalkine/CX3CL1 in MPO-AAV-associated glomerulonephritis rats

    To investigate the expression and significance of Fractalkine (CX3CL1, FKN) in serum and renal tissue of myeloperoxidase and anti-neutrophil cytoplasmic antibody associated vasculitis (MPO-AAV) rats.

    Junxue Ma, Junjie Wang, Hongli Kang, Ruiying Ma, Zhengxi Zhu in BMC Nephrology (2024)

  12. Article

    Open Access

    Association between delayed ambulation and increased risk of adverse events after lumbar fusion surgery in elderly patients

    The relationship between delayed ambulation (DA) and postoperative adverse events (AEs) following transforaminal lumbar interbody fusion (TLIF) in elderly patients remains elusive. The aim of our study was to ...

    Shuai-Kang Wang, **n-Yi Chai, Peng Wang, Chao Kong in BMC Musculoskeletal Disorders (2024)

  13. No Access

    Article

    Sex differences in coronary atherosclerotic plaque activity using 18F-sodium fluoride positron emission tomography

    There are sex differences in the extent, severity, and outcomes of coronary artery disease. We aimed to assess the influence of sex on coronary atherosclerotic plaque activity measured using coronary 18F-sodium f...

    Jacek Kwiecinski, Kang-Ling Wang in European Journal of Nuclear Medicine and M… (2024)

  14. No Access

    Article

    Estrogen-related receptor alpha promotes thyroid tumor cell survival via a tumor subtype-specific regulation of target gene networks

    Mortalin (encoded by HSPA9) is a mitochondrial chaperone often overexpressed in cancer through as-yet-unknown mechanisms. By searching different RNA-sequencing datasets, we found that ESRRA is a transcription fac...

    Wen**g Chen, Young Shin Song, Han Sai Lee, Chien-Wei Lin, Junguee Lee in Oncogene (2024)

  15. No Access

    Article

    High Hydrostatic Pressure Exacerbates Bladder Fibrosis through Activating Piezo1

    Bladder outlet obstruction (BOO) results in significant fibrosis in the chronic stage and elevated bladder pressure. Piezo1 is a type of mechanosensitive (MS) channel that directly responds to mechanical stimu...

    Bo-lang Deng, Dong-xu Lin, Zhi-peng Li, Kang Li, Peng-yu Wei in Current Medical Science (2024)

  16. Article

    Open Access

    Chemotherapy-related cardiotoxicity and its symptoms in patients with breast cancer: a sco** review

    Chemotherapy-related cardiotoxicity is a significant concern because it is a major cause of morbidity. This study aimed to provide in-depth information on the symptoms of chemotherapy-related cardiotoxicity (C...

    Hyunjoo Kim, Bomi Hong, Sanghee Kim, Seok-Min Kang, Jeongok Park in Systematic Reviews (2024)

  17. Article

    Open Access

    Shortness of breath on the day of discharge: an early alert for post-discharge complications in patients undergoing lung cancer surgery

    Symptom assessment based on patient-reported outcome (PRO) can correlate with disease severity, making it a potential tool for threshold alerts of postoperative complications. This study aimed to determine whe...

    Dan Kang, Cheng Lei, Yong Zhang, **ng Wei, Wei Dai in Journal of Cardiothoracic Surgery (2024)

  18. Article

    Open Access

    Wearable sensor-based quantitative gait analysis in Parkinson’s disease patients with different motor subtypes

    Gait impairments are among the most common and disabling symptoms of Parkinson’s disease and worsen as the disease progresses. Early detection and diagnosis of subtype-specific gait deficits, as well as progre...

    Weishan Zhang, Yun Ling, Zhonglue Chen, Kang Ren, Shengdi Chen in npj Digital Medicine (2024)

  19. Article

    Open Access

    Age-specific association between meal-skip** patterns and the risk of hyperglycemia in Korean adults: a national cross-sectional study using the KNHANES data

    Glucose metabolism regulation is influenced by age and meal skip**, although research on their interplay with hyperglycemia remains limited. This study aims to explore the intricate relationship between meal...

    Yeonji Kang, Minji Kang, Hyunjung Lim in BMC Public Health (2024)

  20. No Access

    Article

    A case of crystalglobulin-induced nephropathy wherein M protein was identified by mass spectrometry and immunoglobulin G subclass staining

    Crystalglobulin-induced nephropathy is a rare disease that causes the deposition of crystallized monoclonal immunoglobulins into the glomerular capillary and arteriole spaces. Here, we report the case of a pat...

    Hibiki Mochida, Mizuki Kyoda, Yusuke Ushio, Taku Morito in CEN Case Reports (2024)

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