29 Result(s)
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Open AccessEMT cells increase breast cancer metastasis via paracrine GLI activation in neighbouring tumour cells
Recent fate-map** studies concluded that EMT is not required for metastasis of carcinomas. Here we challenge this conclusion by showing that these studies failed to account for possible crosstalk between EMT...
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Open AccessContinual Antigenic Diversification in China Leads to Global Antigenic Complexity of Avian Influenza H5N1 Viruses
The highly pathogenic avian influenza (HPAI) H5N1 virus poses a significant potential threat to human society due to its wide spread and rapid evolution. In this study, we present a comprehensive antigenic map...
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Open AccessProteome Response of Chicken Embryo Fibroblast Cells to Recombinant H5N1 Avian Influenza Viruses with Different Neuraminidase Stalk Lengths
The variation on neuraminidase (NA) stalk region of highly pathogenic avian influenza H5N1 virus results in virulence change in animals. In our previous studies, the special NA stalk-motif of H5N1 viruses has ...
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Open AccessStatistical and Ontological Analysis of Adverse Events Associated with Monovalent and Combination Vaccines against Hepatitis A and B Diseases
Vaccinations often induce various adverse events (AEs) and sometimes serious AEs (SAEs). While many vaccines are used in combination, the effects of vaccine-vaccine interactions (VVIs) on vaccine AEs are rarel...
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Open AccessQuantitative secondary electron imaging for work function extraction at atomic level and layer identification of graphene
Two-dimensional (2D) materials usually have a layer-dependent work function, which require fast and accurate detection for the evaluation of their device performance. A detection technique with high throughput...
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Open AccessBoosting thermoelectric efficiency using time-dependent control
Thermoelectric efficiency is defined as the ratio of power delivered to the load of a device to the rate of heat flow from the source. Till date, it has been studied in presence of thermodynamic constraints se...
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Open AccessIdentification of cellular microRNA-136 as a dual regulator of RIG-I-mediated innate immunity that antagonizes H5N1 IAV replication in A549 cells
H5N1 influenza A virus (IAV) causes severe respiratory diseases and high mortality rates in animals and humans. MicroRNAs are being increasingly studied to evaluate their potential as therapeutic entities to c...
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Open AccessHigh throughput secondary electron imaging of organic residues on a graphene surface
Surface organic residues inhibit the extraordinary electronic properties of graphene, hindering the development of graphene electronics. However, fundamental understanding of the residue morphology is still ab...
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Open AccessActivating the Microscale Edge Effect in a Hierarchical Surface for Frosting Suppression and Defrosting Promotion
Despite extensive progress, current icephobic materials are limited by the breakdown of their icephobicity in the condensation frosting environment. In particular, the frost formation over the entire surface i...
