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Article
Panax notoginseng saponins induced up-regulation, phosphorylation and binding activity of MEK, ERK, AKT, PI-3K protein kinases and GATA transcription factors in hematopoietic cells
To investigate the effects of panax notoginseng saponins (PNS) on expression, regulation and phosphorylation of multiple protein kinases in mitogen activated protein kinase (MAPK) intracellular signal pathway ...
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Article
Effects of sodium copper chlorophyllin on mesenchymal stem cell function in aplastic anemia mice
To investigate the effects of sodium copper chlorophyllin (SCC) on the proliferation, differentiation and immunomodulatory function of mesenchymal stem cells (MSCs) from mice with aplastic anemia.
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Article
Introduction to the CDEX experiment
It is believed that weakly interacting massive particles (WIMPs) are candidates for dark matter (DM) in our universe which come from outer space and might interact with the standard model (SM) matter of our de...
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Article
Open AccessAn unprecedented (3,4,24)-connected heteropolyoxozincate organic framework as heterogeneous crystalline Lewis acid catalyst for biodiesel production
A novel 3D hexadecanuclear heteropolyoxozincate organic framework, IFMC-200, has been successfully synthesized based on a late transition metal-oxygen cluster. IFMC-200 not only represents the first example of...
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Article
Open AccessRadiofrequency ablation following first-line transarterial chemoembolization for patients with unresectable hepatocellular carcinoma beyond the Milan criteria
Recent studies suggest that a combination of radiofrequency ablation (RFA) and transarterial chemoembolization (TACE) may have theoretical advantages over TACE alone for treatment of hepatocellular carcinoma (...
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Article
Effects of Chitosan, Calcium Chloride, and Pullulan Coating Treatments on Antioxidant Activity in Pear cv. “Huang guan” During Storage
Effects of different calcium chloride, chitosan and pullulan coating treatments on antioxidant activity of “Huang guan” pears (Pyrus pyrifolia Nakai) during storage have been studied. Total phenolic content, phen...
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Article
Open AccessZuo ** Wan reverses P-gp-mediated drug-resistance by inhibiting activation of the PI3K/Akt/NF-κB pathway
Zuo-**-Wan (ZJW), a traditional Chinese medicine formula, has been identified to be effective against drug resistance in cancer. In the present study, we investigated the effect of ZJW on acquired oxaliplatin...
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Article
Review on tactile sensory feedback of prosthetic hands for the upper-limb amputees by sensory afferent stimulation
Loss of sensory function for upper-limb amputees inevitably devastates their life qualities, and lack of reliable sensory feedback is the biggest defect to sophisticated prosthetic hands, greatly hindering the...
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Article
Design of observer-based discrete repetitive-control system based on 2D model
A discrete observer-based repetitive control (RC) design method for a linear system with uncertainties was presented based on two-dimensional (2D) system theory. Firstly, a 2D discrete model was established to...
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Article
Monocyte subsets and monocyte-platelet aggregates in patients with unstable angina
Monocyte subsets and monocyte-platelet aggregates (MPAs) play important role in atherosclerosis and thrombosis. We aimed to determine their changes in patients with unstable angina (UA). In this cross-sectiona...
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Article
Potent in vitro synergism of fusidic acid (FA) and berberine chloride (BBR) against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA)
It was found in the present study that combined use of fusidic acid (FA) and berberine chloride (BBR) offered an in vitro synergistic action against 7 of the 30 clinical methicillin-resistant Staphylococcus aureu...
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Article
HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β
Cellular DNA repair processes are crucial to maintain genome stability and integrity. In DNA base excision repair, a tight heterodimer complex formed by DNA polymerase β (Polβ) and XRCC1 is thought to facilita...
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Article
Long-term outcomes and prognostic analysis of radiofrequency ablation for small hepatocellular carcinoma: 10-year follow-up in Chinese patients
Radiofrequency ablation (RFA) has been used as a curative therapy for small hepatocellular carcinoma (HCC). However, relatively little is known about the long-term outcome of RFA for small HCC in a background ...
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Article
Chronic nicotine treatment enhances vascular smooth muscle relaxation in rats
To investigate the effect of chronic nicotine treatment on vascular function and to identify the underlying mechanisms.
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Article
Feasibility of Ultrafast Intermolecular Single-Quantum Coherence Spectroscopy in Analysis of Viscous-Liquid Foods
A newly developed nuclear magnetic resonance (NMR) technique, ultrafast intermolecular single-quantum coherence (UF iSQC) spectroscopy, demonstrated its potentials to obtain spectra of viscous-liquid samples i...
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Article
Open AccessRoles of NMDA and dopamine in food-foraging decision-making strategies of rats in the social setting
In highly complex social settings, an animal’s motivational drive to pursue an object depends not only on the intrinsic properties of the object, but also on whether the decision-making animal perceives an ob...
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Article
Open AccessXXIV World Allergy Congress 2015
A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts
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Article
Genetic analysis of glume hairiness (Hg) gene in bread wheat (Triticum aestivum L.)
Hairiness is a common character in planta. Glume hairiness (Hg) is present in the full spectrum of bread wheat and its close relatives and was mainly studied in phenotypic diversity, species evolution, and map...
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Article
Natural Xanthones from Garcinia mangostana with Multifunctional Activities for the Therapy of Alzheimer’s Disease
Natural xanthones have diversity pharmacological activities. Here, a series of xanthones isolated from the pericarps of Garcinia mangostana Linn, named α-Mangostin, 8-Deoxygartanin, Gartanin, Garciniafuran, Garci...
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Article
Gartanin Protects Neurons against Glutamate-Induced Cell Death in HT22 Cells: Independence of Nrf-2 but Involvement of HO-1 and AMPK
Oxidative stress mediates the pathogenesis of neurodegenerative disorders. Gartanin, a natural xanthone of mangosteen, possesses multipharmacological activities. Herein, the neuroprotection capacity of gartani...
