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Article
Machine Learning for Brain Imaging Genomics Methods: A Review
In the past decade, multimodal neuroimaging and genomic techniques have been increasingly developed. As an interdisciplinary topic, brain imaging genomics is devoted to evaluating and characterizing genetic va...
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Article
Open AccessAuthor Correction: Inferring time-varying generation time, serial interval, and incubation period distributions for COVID-19
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Article
Open AccessInferring time-varying generation time, serial interval, and incubation period distributions for COVID-19
The generation time distribution, reflecting the time between successive infections in transmission chains, is a key epidemiological parameter for describing COVID-19 transmission dynamics. However, because ex...
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Article
Open AccessScaling-up and proteomic analysis reveals photosynthetic and metabolic insights toward prolonged H2 photoproduction in Chlamydomonas hpm91 mutant lacking proton gradient regulation 5 (PGR5)
Clean and sustainable H2 production is crucial to a carbon–neutral world. H2 generation by Chlamydomonas reinhardtii is an attractive approach for solar-H2 from H2O. However, it is currently not large-scalable be...
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Article
Transcriptional Regulatory Mechanism of Differential Metabolite Formation in Root and Stem of Ephedra sinica
Ephedra sinica, a well-known Chinese medicinal plant, is characterized as having the opposite medicinal effect among its root and stem. However, there is a lack of understanding to differentiate the active compon...
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Article
Mechanism of progressive failure of a slope with a steep joint under the action of freezing and thawing: model test
The stability of slope rock masses is influenced by freeze-thaw cycles in cold region, and the mechanism of stability deterioration is not clear. In order to understand the damage and progressive failure chara...
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Article
Open AccessMetabolic differences in women with premature ovarian insufficiency: a systematic review and meta-analysis
This review aimed to investigate the metabolic profile of women with premature ovarian insufficiency (POI) compared relative to women with normal ovarian functioning.
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Article
Open AccessVisualization of rotational symmetry breaking electronic states in MnBi2Te4 and MnBi4Te7
The Mn-Bi-Te class of compounds are recently discovered topological insulators with broken time-reversal-symmetry, which host unique quantum anomalous Hall and axion insulator states. Their key characteristics...
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Article
Major osteoporosis fracture prediction in type 2 diabetes: a derivation and comparison study
The widely recommended fracture prediction tool FRAX was developed based on and for the general population. Although several adjusted FRAX methods were suggested for type 2 diabetes (T2DM), they still need to ...
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Article
Open AccessDNA damage-induced paraspeckle formation enhances DNA repair and tumor radioresistance by recruiting ribosomal protein P0
Paraspeckles are mammal-specific membraneless nuclear bodies that participate in various biological processes. NONO, a central paraspeckle component, has been shown to play pivotal roles in DNA double-strand b...
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Article
Preparation and Adsorption Performance of Nano-hydroxyapatite-Enhanced Acrylamide Hydrogel Adsorbent
In this study, a hydrogel adsorbent was successfully synthesized using hydroxyapatite/acrylamide/β-cyclodextrin to adsorb heavy metal ions and dyes in water. In the study, different contents of hydroxyapatite ...
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Article
Open AccessMetabolomic strategies and biochemical analysis of the effect of processed Rehmanniae radix extract on a blood-deficient rat model
Rehmanniae Radix (RR), an herb with numerous pharmacological effects, is widely used in traditional Chinese medicine for the treatment of blood deficiency syndrome, either alone or in combination with other herbs...
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Article
Open AccessAged bone matrix-derived extracellular vesicles as a messenger for calcification paradox
Adipocyte differentiation of bone marrow mesenchymal stem/stromal cells (BMSCs) instead of osteoblast formation contributes to age- and menopause-related marrow adiposity and osteoporosis. Vascular calcificati...
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Article
Ti3C2Tx MXene for organic/perovskite optoelectronic devices
MXenes are emerging two-dimensional (2D) nanomaterials composed of transition metal carbides and/or nitrides and possess unique layered structures with abundant surface functional groups, which enable them wit...
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Article
Impact of Low Frequency Electro-acupuncture on Glucose and Lipid Metabolism in Unmarried PCOS Women: A Randomized Controlled Trial
To explore the effect of electro-acupuncture (EA) on glucose and lipid metabolism in unmarried patients with polycystic ovary syndrome (PCOS).
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Article
Open AccessRetraction Note: MicroRNA-506 inhibits tumor growth and metastasis in nasopharyngeal carcinoma through the inactivation of the Wnt/β-catenin signaling pathway by downregulating LHX2
This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s13046-019-1023-4.
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Article
Comparative transcriptome analysis of the hyperaccumulator plant Phytolacca americana in response to cadmium stress
To study the molecular mechanism of the hyperaccumulator plant Phytolacca americana against cadmium (Cd) stress, the leaves of P. americana treated with 400 μM Cd for 0, 2, 12, and 24 h were harvested for compara...
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Article
Open AccessPRMT1 enhances oncogenic arginine methylation of NONO in colorectal cancer
Arginine methylation is an important posttranslational modification catalyzed by protein arginine methyltransferases (PRMTs). However, the role of PRMTs in colorectal cancer (CRC) progression is not well under...
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Article
Open AccessGut microbiota-derived propionate mediates the neuroprotective effect of osteocalcin in a mouse model of Parkinson’s disease
Parkinson’s disease (PD) is a neurodegenerative disorder with no absolute cure. The evidence of the involvement of gut microbiota in PD pathogenesis suggests the need to identify certain molecule(s) derived fr...
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Article
Metal halide perovskites for light-emitting diodes
Metal halide perovskites have shown promising optoelectronic properties suitable for light-emitting applications. The development of perovskite light-emitting diodes (PeLEDs) has progressed rapidly over the pa...
