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Article
Open AccessIntegrated analysis of transcriptome and small RNAome reveals regulatory network of rapid and long-term response to heat stress in Rhododendron moulmainense
The post-transcriptional gene regulatory pathway and small RNA pathway play important roles in regulating the rapid and long-term response of Rhododendron moulmainense to high-temperature stress.
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Article
Open AccessDigital health literacy and associated factors among internet users from China: a cross-sectional study
As the internet develops and 5G technology becomes increasingly prominent, the internet has become a major source of health-related information. Increasingly, people use the internet to find health-related inf...
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Article
Open AccessLactobacillus rhamnosus GG ameliorates hyperuricemia in a novel model
Hyperuricemia (HUA) is a metabolic syndrome caused by abnormal purine metabolism. Although recent studies have noted a relationship between the gut microbiota and gout, whether the microbiota could ameliorate ...
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Article
Open AccessLow pressure reversibly driving colossal barocaloric effect in two-dimensional vdW alkylammonium halides
Plastic crystals as barocaloric materials exhibit the large entropy change rivalling freon, however, the limited pressure-sensitivity and large hysteresis of phase transition hinder the colossal barocaloric ef...
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Article
Open AccessVentral Hippocampal CA1 Pyramidal Neurons Encode Nociceptive Information
As a main structure of the limbic system, the hippocampus plays a critical role in pain perception and chronicity. The ventral hippocampal CA1 (vCA1) is closely associated with negative emotions such as anxiet...
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Article
Open AccessDual-modal radiomics nomogram based on contrast-enhanced ultrasound to improve differential diagnostic accuracy and reduce unnecessary biopsy rate in ACR TI-RADS 4–5 thyroid nodules
American College of Radiology (ACR) Thyroid Imaging Reporting and Data System (TI-RADS, TR) 4 and 5 thyroid nodules (TNs) demonstrate much more complicated and overlap** risk characteristics than TR1-3 and h...
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Article
Open AccessIncreased cysteinyl-tRNA synthetase drives neuroinflammation in Alzheimer’s disease
Microglia-mediated neuroinflammation in Alzheimer’s disease (AD) is not only a response to pathophysiological events, but also plays a causative role in neurodegeneration. Cytoplasmic cysteinyl-tRNA synthetase...
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Article
Open AccessTMEM63B channel is the osmosensor required for thirst drive of interoceptive neurons
Thirst plays a vital role in the regulation of body fluid homeostasis and if deregulated can be life-threatening. Interoceptive neurons in the subfornical organ (SFO) are intrinsically osmosensitive and their ...
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Article
Effect of slow shot speed on externally solidified crystal, porosity and tensile property in a newly developed high-pressure die-cast Al-Si alloy
The effect of slow shot speed on externally solidified crystal (ESC), porosity and tensile property in a newly developed high-pressure die-cast Al-Si alloy was investigated by optical microscopy (OM), scanning...
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Article
The relationship between parent–child communication and English academic engagement among middle school students: a moderated mediation model
This study constructed a moderated mediation model to explore the impact of parent–child communication on English academic engagement. We conducted a questionnaire survey among 21,270 middle school students us...
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Open AccessCorrection: A cross-sectional study: family communication, anxiety, and depression in adolescents: the mediating role of family violence and problematic internet use
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Article
Open AccessUse of airway pressure-based indices to detect high and low inspiratory effort during pressure support ventilation: a diagnostic accuracy study
Assessment of the patient’s respiratory effort is essential during assisted ventilation. We aimed to evaluate the accuracy of airway pressure (Paw)-based indices to detect potential injurious inspiratory effort d...
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Open AccessDemography and fitness of Sesamia inferens Walker (Lepidoptera: Noctuidae) on three important gramineous crops
Pink stem borer, Sesamia inferens (Walker), a major rice pest, has rarely been reported to cause serious damage to sorghum in China. During a survey of insect pests in glutinous sorghum for Chinese liquor product...
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Open AccessMicrobiome and metabolome features in inflammatory bowel disease via multi-omics integration analyses across cohorts
The perturbations of the gut microbiota and metabolites are closely associated with the progression of inflammatory bowel disease (IBD). However, inconsistent findings across studies impede a comprehensive und...
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Article
Open AccessMagnetic resonance imaging of knees: a novel approach to predict recombinant human growth hormone therapy response in short-stature children in late puberty
There is no appropriate tool to predict recombinant human growth hormone (rhGH) response before therapy initiation in short-stature children in late puberty. The current study aimed to explore the associations...
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Article
Open AccessTheoretical corrections of \(R_D\) and \(R_{D^*}\)
\(R_{D^{(*)}}\) R D ...
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Open AccessResearch on the development methodology for clinical practice guidelines for organic integration of traditional Chinese and Western medicine
Integrated traditional Chinese medicine (TCM) and Western medicine (WM) is a new medical science grounded in the knowledge bases of both TCM and WM, which then forms a unique modern medical system in China. In...
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Article
Open AccessThe changes of neuroactivity of Tui Na (Chinese massage) at Hegu acupoint on sensorimotor cortex in stroke patients with upper limb motor dysfunction: a fNIRS study
Tui Na (Chinese massage) is a relatively simple, inexpensive, and non-invasive intervention, and has been used to treat stroke patients for many years in China. Tui Na acts on specific parts of the body which ...
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Article
Open AccessNearby fault interaction within the double-vergence suture in eastern Taiwan during the 2022 Chihshang earthquake sequence
Nearby faults interact through stress changes induced by fault slip and viscoelastic flow. The process is, however, often elusive and can be geometry-dependent and time-variant. Here, we combine geodetic and f...
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Article
Open AccessChronic cough relief by allosteric modulation of P2X3 without taste disturbance
P2X receptors are cation channels that sense extracellular ATP. Many therapeutic candidates targeting P2X receptors have begun clinical trials or acquired approval for the treatment of refractory chronic cough...
