200 Result(s)
within
**an-ming Wu
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessGut butyrate-producers confer post-infarction cardiac protection
The gut microbiome and its metabolites are increasingly implicated in several cardiovascular diseases, but their role in human myocardial infarction (MI) injury responses have yet to be established. To address...
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Open AccessA longitudinal resource for population neuroscience of school-age children and adolescents in China
During the past decade, cognitive neuroscience has been calling for population diversity to address the challenge of validity and generalizability, ushering in a new era of population neuroscience. The develop...
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Open AccessEvaluation on coupling coordinated development of population economy and eco-geological environment in the twin-city economic circle of Chengdu–Chongqing region
Using the CRITIC method, comprehensive index evaluation method, VAR model, coupling coordination model and other methods, this paper evaluates the comprehensive development of the population economy and eco-ge...
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Open AccessResolving nanostructure and chemistry of solid-electrolyte interphase on lithium anodes by depth-sensitive plasmon-enhanced Raman spectroscopy
The solid-electrolyte interphase (SEI) plays crucial roles for the reversible operation of lithium metal batteries. However, fundamental understanding of the mechanisms of SEI formation and evolution is still ...
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Open AccessGenome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population
Lung adenocarcinoma is the most common type of lung cancer. Known risk variants explain only a small fraction of lung adenocarcinoma heritability. Here, we conducted a two-stage genome-wide association study o...
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Open AccessSocial and moral psychology of COVID-19 across 69 countries
The COVID-19 pandemic has affected all domains of human life, including the economic and social fabric of societies. One of the central strategies for managing public health throughout the pandemic has been th...
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Open AccessPrenatal DEHP exposure predicts neurological disorders via transgenerational epigenetics
Recent experimental and observational research has suggested that childhood allergic asthma and other conditions may be the result of prenatal exposure to environmental contaminants, such as di-(2-ethylhexyl) ...
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Open AccessWhole microbe arrays accurately predict interactions and overall antimicrobial activity of galectin-8 toward distinct strains of Streptococcus pneumoniae
Microbial glycan microarrays (MGMs) populated with purified microbial glycans have been used to define the specificity of host immune factors toward microbes in a high throughput manner. However, a limitation ...
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Open AccessUse of dual genomic sequencing to screen mitochondrial diseases in pediatrics: a retrospective analysis
Mitochondrial diseases (MDs) were a large group multisystem disorders, attributable in part to the dual genomic control. The advent of massively sequencing has improved diagnostic rates and speed, and was incr...
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Open AccessAllergic rhinitis children with obesity are more vulnerable to air pollution: a cross sectional study
The association between air pollution, allergic rhinitis (AR), and obesity has not been studied. From 2007 to 2011, 52 obese and 152 non-obese children (7–17 years old) with AR were recruited. Pediatric-Rhinoc...
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Open AccessControl of SARS-CoV-2 infection by MT1-MMP-mediated shedding of ACE2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global pandemic. Angiotensin-converting enzyme 2 (ACE2) is an entry receptor for SARS-CoV-2. The full-length membrane form of ACE2 (mem...
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Open AccessTracking westerly wind directions over Europe since the middle Holocene
The variability of the northern westerlies has been considered as one of the key elements for modern and past climate evolution. Their multiscale behavior and underlying control mechanisms, however, are incomp...
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Open AccessPredicting willingness to donate blood based on machine learning: two blood donor recruitments during COVID-19 outbreaks
Machine learning methods are a novel way to predict and rank donors' willingness to donate blood and to achieve precision recruitment, which can improve the recruitment efficiency and meet the challenge of blo...
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Open AccessA synthetic transcription platform for programmable gene expression in mammalian cells
Precise, scalable, and sustainable control of genetic and cellular activities in mammalian cells is key to develo** precision therapeutics and smart biomanufacturing. Here we create a highly tunable, modular...
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Open AccessInsular cortical circuits as an executive gateway to decipher threat or extinction memory via distinct subcortical pathways
Threat and extinction memories are crucial for organisms’ survival in changing environments. These memories are believed to be encoded by separate ensembles of neurons in the brain, but their whereabouts remai...
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Open AccessSGLT2 inhibitors attenuate nephrin loss and enhance TGF-β1 secretion in type 2 diabetes patients with albuminuria: a randomized clinical trial
To evaluate the effect of SGLT2 inhibitor (SGLT2i) on albuminuria, nephrin (NPH) and transforming-growth-factor-beta1 (TGF-β1) levels in urine and low-grade inflammation in type 2 diabetes (T2D) patients. A rando...
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Open AccessPhenylalanine impairs insulin signaling and inhibits glucose uptake through modification of IRβ
Whether amino acids act on cellular insulin signaling remains unclear, given that increased circulating amino acid levels are associated with the onset of type 2 diabetes (T2D). Here, we report that phenylalan...
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Open AccessStomatin modulates adipogenesis through the ERK pathway and regulates fatty acid uptake and lipid droplet growth
Regulation of fatty acid uptake, lipid production and storage, and metabolism of lipid droplets (LDs), is closely related to lipid homeostasis, adipocyte hypertrophy and obesity. We report here that stomatin, ...
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Open AccessIncreasing salinity stress decreases the thermal tolerance of amphibian tadpoles in coastal areas of Taiwan
Global warming is the main cause for the rise of both global temperatures and sea-level, both major variables threatening biodiversity. Rising temperatures threaten to breach the thermal limits of organisms wh...
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Open AccessGeospatial characterization of rural settlements and potential targets for revitalization by geoinformation technology
To better implement the Strategy of Rural Revitalization, it is essential to characterize the rural settlements and understand their roles in the socio-environmental interactive system. This paper is hence aim...
