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  1. Article

    Open Access

    Uncertainty-inspired open set learning for retinal anomaly identification

    Failure to recognize samples from the classes unseen during training is a major limitation of artificial intelligence in the real-world implementation for recognition and classification of retinal anomalies. W...

    Meng Wang, Tian Lin, Lianyu Wang, Aidi Lin, Ke Zou, **nxing Xu in Nature Communications (2023)

  2. Article

    Open Access

    Neuro-inspired optical sensor array for high-accuracy static image recognition and dynamic trace extraction

    Neuro-inspired vision systems hold great promise to address the growing demands of mass data processing for edge computing, a distributed framework that brings computation and data storage closer to the source...

    Pei-Yu Huang, Bi-Yi Jiang, Hong-Ji Chen, Jia-Yi Xu, Kang Wang in Nature Communications (2023)

  3. Article

    Open Access

    Oncometabolite D-2-hydroxyglutarate—dependent metabolic reprogramming induces skeletal muscle atrophy during cancer cachexia

    Cancer cachexia is characterized by weight loss and skeletal muscle wasting. Based on the up-regulation of catabolism and down-regulation of anabolism, here we showed genetic mutation-mediated metabolic reprog...

    **nting Zhu, Juan Hao, Hong Zhang, Mengyi Chi, Yaxian Wang in Communications Biology (2023)

  4. Article

    Open Access

    Correction to: Association between the triglyceride-glucose index and the risk of mortality among patients with chronic heart failure: results from a retrospective cohort study in China

    You Zhou, Chi Wang, Hebin Che, Liting Cheng, Di Zhu in Cardiovascular Diabetology (2023)

  5. Article

    Open Access

    Single-cell transcriptome analysis indicates fatty acid metabolism-mediated metastasis and immunosuppression in male breast cancer

    Male breast cancer (MBC) is a rare but aggressive malignancy with cellular and immunological characteristics that remain unclear. Here, we perform transcriptomic analysis for 111,038 single cells from tumor ti...

    Handong Sun, Lishen Zhang, Zhonglin Wang, Danling Gu, Mengyan Zhu in Nature Communications (2023)

  6. Article

    Open Access

    Non-volatile optoelectronic memory based on a photosensitive dielectric

    Recently, the optoelectronic memory is capturing growing attention due to its integrated function of sense and memory as well as multilevel storage ability. Although tens of states have been reported in litera...

    Rui Zhu, Huili Liang, Shangfeng Liu, Ye Yuan, **nqiang Wang in Nature Communications (2023)

  7. Article

    Open Access

    Dissecting peri-implantation development using cultured human embryos and embryo-like assembloids

    Studies of cultured embryos have provided insights into human peri-implantation development. However, detailed knowledge of peri-implantation lineage development as well as underlying mechanisms remains obscur...

    Zongyong Ai, Baohua Niu, Yu Yin, Lifeng **ang, Gaohui Shi, Kui Duan in Cell Research (2023)

  8. Article

    Open Access

    Ground magnetic survey on Mars from the Zhurong rover

    Mars’ magnetic field has been measured at large scale by orbiting spacecraft and at very small scale via Martian meteorites. Here we report on a ground magnetic survey on metre to kilometre scales. The Zhurong...

    Aimin Du, Yasong Ge, Huapei Wang, Haiying Li, Ying Zhang, Hao Luo in Nature Astronomy (2023)

  9. Article

    Open Access

    Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate Vγ9Vδ2 T cells

    In both cancer and infections, diseased cells are presented to human Vγ9Vδ2 T cells through an ‘inside out’ signalling process whereby structurally diverse phosphoantigen (pAg) molecules are sensed by the intr...

    Linjie Yuan, **anqiang Ma, Yunyun Yang, Yingying Qu, **n Li, **aoyu Zhu in Nature (2023)

  10. Article

    Open Access

    6-Year trajectory of fasting plasma glucose (FPG) and mortality risk among individuals with normal FPG at baseline: a prospective cohort study

    Higher fasting plasma glucose (FPG) levels were associated with an increased risk of all-cause mortality; however, the associations between long-term FPG trajectory groups and mortality were unclear, especiall...

    Wanlu Li, Chi Pang Wen, Wenyuan Li, Zhijun Ying in Diabetology & Metabolic Syndrome (2023)

  11. Article

    Open Access

    Earliest ceramic drainage system and the formation of hydro-sociality in monsoonal East Asia

    The earliest ceramic drainage system unearthed at the **liangtai site on the Central Plains of China represents an unprecedented social and environmental manipulation as societies faced surging environmental...

    Chunxia Li, Yanpeng Cao, Chi Zhang, Ling Qin, Zhenhua Deng, Yan Chen in Nature Water (2023)

  12. Article

    Open Access

    Differences in foot shape when wearing wedge-heeled shoes with elevated forefoot height and heel height

    Wedge-heeled shoes, which are formed by elevating both the forefoot and heel, have been popular among young women. However, research on the foot shape in wedge-heeled shoes is lacking. This study aimed to acce...

    Ao Zhu, Yu-Chi Lee in Fashion and Textiles (2023)

  13. Article

    Open Access

    Reconstruction of interactions in the ProtoDUNE-SP detector with Pandora

    The Pandora Software Development Kit and algorithm libraries provide pattern-recognition logic essential to the reconstruction of particle interactions in liquid argon time projection chamber detectors. Pandor...

    A. Abed Abud, B. Abi, R. Acciarri, M. A. Acero in The European Physical Journal C (2023)

  14. Article

    Open Access

    Clinical significance of B7-H3 expression in circulating CD4+CD25high T cells, CD14+ monocytes, and plasma for the progression of HIV infection

    B7-H3 is an important immune checkpoint molecule that plays a negative role in immune regulation. This study was aimed to explore B7-H3 expression in HIV-infected patients and its clinical significance.

    Jun-Chi Xu, Hui Chen, ** Xu, **n-Ran You, Geng-chao Zhu in BMC Infectious Diseases (2023)

  15. Article

    Open Access

    Genome-wide association studies identify OsWRKY53 as a key regulator of salt tolerance in rice

    Salinity stress progressively reduces plant growth and productivity, while plant has developed complex signaling pathways to confront salt stress. However, only a few genetic variants have been identified to m...

    Jun Yu, Chengsong Zhu, Wei Xuan, Hongzhou An, Yunlu Tian in Nature Communications (2023)

  16. Article

    Open Access

    circDYRK1A tethers biological behaviors of gastric carcinoma using novel bioinformatics analysis and experimental validations

    Gastric cancer has been one of the wide public health burdens with its high morbidity and mortality over several decades. As the unconventional modules among RNA families, circular RNAs present their blazing b...

    Zirui Zhu, Huiwen Lu, Xu Zhao, Yimeng Sun, Junqiao Yao, Chi Xue in Scientific Reports (2023)

  17. Article

    Open Access

    Exploiting synergistic effect of CO/NO gases for soft tissue transplantation using a hydrogel patch

    Autologous skin flap transplantation is a common method for repairing complex soft tissue defects caused by cancer, trauma, and congenital malformations. Limited blood supply range and post-transplantation isc...

    **aoduo Tang, **gyan Ren, **n Wei, Tao Wang, Haiqiu Li, Yihan Sun in Nature Communications (2023)

  18. Article

    Open Access

    Impaired glymphatic drainage underlying obstructive sleep apnea is associated with cognitive dysfunction

    Obstructive sleep apnea (OSA) is highly prevalent but easily undiagnosed and is an independent risk factor for cognitive impairment. However, it remains unclear how OSA is linked to cognitive impairment. In th...

    Jiuqi Wang, Yiming Tian, Chi Qin, Lin Meng, Renyi Feng, Shuqin Xu in Journal of Neurology (2023)

  19. Article

    Open Access

    CACA guidelines for holistic integrative management of rectal cancer

    Colorectal cancer is a common malignant tumor worldwide. In China, the ratio of rectal cancer to colon cancer in terms of incidence is close to 1: 1. Low rectal cancer accounts for more than half of all cases ...

    Guiyu Wang, Daiming Fan, ** Gu, Kefeng Ding, Xuedong Fang in Holistic Integrative Oncology (2023)

  20. Article

    Open Access

    A lesion-selective albumin-CTLA4Ig as a safe and effective treatment for collagen-induced arthritis

    CTLA4Ig is a dimeric fusion protein of the extracellular domain of cytotoxic T-lymphocyte protein 4 (CTLA4) and an Fc (Ig) fragment of human IgG1 that is approved for treating rheumatoid arthritis. However, CTLA4...

    Fu-Yao Jiang, Yan-Zhu Zhang, Yuan-Hong Tai, Chien-Yu Chou in Inflammation and Regeneration (2023)

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