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  1. Article

    Open Access

    Host and viral determinants for efficient SARS-CoV-2 infection of the human lung

    Understanding the factors that contribute to efficient SARS-CoV-2 infection of human cells may provide insights on SARS-CoV-2 transmissibility and pathogenesis, and reveal targets of intervention. Here, we ana...

    Hin Chu, Bingjie Hu, **ner Huang, Yue Chai, Dongyan Zhou in Nature Communications (2021)

  2. Article

    Open Access

    Characteristics and outcomes of patients admitted to adult intensive care units in Hong Kong: a population retrospective cohort study from 2008 to 2018

    Globally, mortality rates of patients admitted to the intensive care unit (ICU) have decreased over the last two decades. However, evaluations of the temporal trends in the characteristics and outcomes of ICU ...

    Lowell Ling, Chun Ming Ho, Pauline Yeung Ng in Journal of Intensive Care (2021)

  3. No Access

    Chapter and Conference Paper

    The Design and Development of School Visitor Information Management System: Malaysia Perspective

    Visitors especially unwelcome visitors may pose possible risks to school children at school. This leads school administrators to reinforce their school visitor management procedures. Current visitor registrati...

    Check-Yee Law, Yong-Wee Sek, Choo-Chuan Tay in Intelligent Human Computer Interaction (2021)

  4. Article

    Open Access

    Convallatoxin enhance the ligand-induced mu-opioid receptor endocytosis and attenuate morphine antinociceptive tolerance in mice

    Morphine is a unique opioid analgesic that activates the mu-opioid receptor (MOR) without efficiently promoting its endocytosis that may underlie side effects. Our objective was to discover a novel enhancer of...

    Po-Kuan Chao, Hsiao-Fu Chang, Li-Chin Ou, Jian-Ying Chuang in Scientific Reports (2019)

  5. No Access

    Article

    Racial Disparities in Revision Total Knee Arthroplasty: Analysis of 125,901 Patients in National US Private Payer Database

    There is a relative paucity of studies that characterized racial disparities in revision total knee arthroplasty (TKA). Therefore, this study was specifically conducted to evaluate the following: (1) incidence...

    Martin Roche, Tsun yee Law, Assem A. Sultan in Journal of Racial and Ethnic Health Dispar… (2019)

  6. No Access

    Article

    Non-nociceptive roles of opioids in the CNS: opioids’ effects on neurogenesis, learning, memory and affect

    Mortality due to opioid use has grown to the point where, for the first time in history, opioid-related deaths exceed those caused by car accidents in many states in the United States. Changes in the prescribi...

    Cherkaouia Kibaly, Chi Xu, Catherine M. Cahill in Nature Reviews Neuroscience (2019)

  7. Article

    Open Access

    Engineering of Hybrid Nanoporous Anodic Alumina Photonic Crystals by Heterogeneous Pulse Anodization

    In this study, we present an advanced nanofabrication approach, so-called ‘heterogeneous pulse anodization’ (HPA), in which galvanostatic stepwise and apodized sinusoidal pulse anodizations are combined in a s...

    Siew Yee Lim, Cheryl Suwen Law, Lluís F. Marsal, Abel Santos in Scientific Reports (2018)

  8. Article

    Open Access

    Efficient production of secretory Streptomyces clavuligerus β-lactamase inhibitory protein (BLIP) in Pichia pastoris

    β-Lactamase inhibitory protein (BLIP), a low molecular weight protein from Streptomyces clavuligerus, has a wide range of potential applications in the fields of biotechnology and pharmaceutical industry because ...

    Kin-Ho Law, Man-Wah Tsang, Yuk-Ki Wong, Ming-San Tsang, Pui-Yee Lau in AMB Express (2018)

  9. No Access

    Chapter

    Sensor-Based Soft Tissue Balancing in Total Knee Arthroplasty

    Total knee arthroplasty (TKA) is a highly successful procedure with utilization expected to grow substantially over the coming decades. However, the revision burden has not concurrently improved, with over 30%...

    Jimmy Chow, Tsun Yee Law, Martin Roche in Intelligent Orthopaedics (2018)

  10. Article

    Open Access

    31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

    Andreas Lundqvist, Vincent van Hoef, **aonan Zhang in Journal for ImmunoTherapy of Cancer (2016)

  11. Article

    Open Access

    Opioid doses required for pain management in lung cancer patients with different cholesterol levels: negative correlation between opioid doses and cholesterol levels

    Pain management has been considered as significant contributor to broad quality-of-life improvement for cancer patients. Modulating serum cholesterol levels affects analgesia abilities of opioids, important pa...

    Zhenhua Huang, Lining Liang, Lingyu Li, Miao Xu, **ang Li in Lipids in Health and Disease (2016)

  12. No Access

    Book

    Surface Wetting

    Characterization, Contact Angle, and Fundamentals

    Kock-Yee Law, Hong Zhao (2016)

  13. No Access

    Chapter

    Terminologies and Definitions

    One of the weak links in surface research has been the lack of clear, well-defined terminologies, definitions, and common language. This at least in part contributes to the current messiness in the surface lit...

    Kock-Yee Law, Hong Zhao in Surface Wetting (2016)

  14. No Access

    Chapter

    Summary and Final Remarks

    Many believe that the concept of wetting begins with the Young’s equation. Although the Young’s equation is very simple, it has been a source of arguments over the last two centuries because the equation compr...

    Kock-Yee Law, Hong Zhao in Surface Wetting (2016)

  15. No Access

    Chapter

    Background

    Studies of surface and liquid–solid interaction have always been an important branch of science, and its role just increases exponentially due to the expanded application of digital printing. To date, due to t...

    Kock-Yee Law, Hong Zhao in Surface Wetting (2016)

  16. No Access

    Chapter

    Wetting on Flat and Smooth Surfaces

    The Young’s contact angle gives a notion of wettability when a liquid wets and spreads on a solid surface. However, it is also a source of arguments and controversies in the literature. The objective of this c...

    Kock-Yee Law, Hong Zhao in Surface Wetting (2016)

  17. No Access

    Chapter

    What Do Contact Angles Measure?

    Contact angle measurement has widely been used to characterize the properties of solid surfaces and study liquid–surface interactions. It has been known for some time that, while the measurement itself is dece...

    Kock-Yee Law, Hong Zhao in Surface Wetting (2016)

  18. No Access

    Chapter

    Determination of Solid Surface Tension by Contact Angle

    In this chapter, approaches to determine solid surface tension by contact angle are briefly reviewed and assessed. These approaches include the Zisman method, various versions of the surface tension component ...

    Kock-Yee Law, Hong Zhao in Surface Wetting (2016)

  19. No Access

    Article

    Effects of addictive drugs on adult neural stem/progenitor cells

    Neural stem/progenitor cells (NSPCs) undergo a series of developmental processes before giving rise to newborn neurons, astrocytes and oligodendrocytes in adult neurogenesis. During the past decade, the role o...

    Chi Xu, Horace H. Loh, **-Yee Law in Cellular and Molecular Life Sciences (2016)

  20. No Access

    Chapter

    Contact Angle Measurements and Surface Characterization Techniques

    Contact angle measurement has been an indispensable tool for surface characterization and wetting study due to its simplicity and versatility. In this chapter, major measurement techniques for static contact a...

    Kock-Yee Law, Hong Zhao in Surface Wetting (2016)

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