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6,099 Result(s)
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Article
Realizing high thermoelectric performance flexible free-standing PEDOT:PSS/Bi0.5Sb1.5Te3 composite films for power generation
Flexible thermoelectrics provide a distinct solution for develo** sustainable and portable power supplies. Inorganic/organic material compositing is an effective strategy to induce a significant enhancement ...
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Open AccessBiparatopic anti-PCSK9 antibody enhances the LDL-uptake in HepG2 cells
Proprotein convertase subtilisin/kexin type 9 (PCSK9) has emerged as a promising therapeutic target to reduce lipids. In 2020, we reported a chimeric camelid-human heavy chain antibody VHH-B11-Fc targeting PCS...
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Research on effect of anode microstructures on mass transfer and electrochemical reaction in SOFCs based on a fractional Brownian motion model
The microstructure of the porous anode plays a crucial role in the mass transfer dynamics and electrochemical reaction of solid oxide fuel cells (SOFCs), significantly impacting their performance. This paper i...
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A new tau dephosphorylation-targeting chimera for the treatment of tauopathies
Abnormal accumulation of hyperphosphorylated tau protein plays a pivotal role in a collection of neurodegenerative diseases named tauopathies, including Alzheimer’s disease (AD). We have recently conceptualize...
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Open AccessIdentification of a novel lactylation-related gene signature predicts the prognosis of multiple myeloma and experiment verification
Multiple myeloma (MM) is an incurable hematological malignancy with poor survival. Accumulating evidence reveals that lactylation modification plays a vital role in tumorigenesis. However, research on lactylat...
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PAFAH2 suppresses synchronized ferroptosis to ameliorate acute kidney injury
Synchronized ferroptosis contributes to nephron loss in acute kidney injury (AKI). However, the propagation signals and the underlying mechanisms of the synchronized ferroptosis for renal tubular injury remain...
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Open AccessmiR-548ag promotes DPP4 expression in hepatocytes through activation of TLR(7/8)/NF-κB pathway
In our previous study, we identified a notable increase in miR-548ag content after obesity, which contributes to the progression of Type 2 diabetes Mellitus(T2DM) through the up-regulation of Dipeptidyl Peptid...
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Selection dictates the distance pattern of similarity in trees and soil fungi across forest ecosystems
How the four major processes affecting community assembly—selection, dispersal, drift, and diversification—solely or jointly shape co-occurring assemblages of macro- and microorganisms at the same scales remai...
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Open AccessPEX3 promotes regenerative repair after myocardial injury in mice through facilitating plasma membrane localization of ITGB3
The peroxisome is a versatile organelle that performs diverse metabolic functions. PEX3, a critical regulator of the peroxisome, participates in various biological processes associated with the peroxisome. Whe...
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Gastric Cancer Mesenchymal Stem Cells Trigger Endothelial Cell Functional Changes to Promote Cancer Progression
Our previous studies have highlighted the pivotal role of gastric cancer mesenchymal stem cells (GCMSCs) in tumor initiation, progression, and metastasis. In parallel, it is well-documented that endothelial ce...
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Calibration method of spectroradiometer based on direct solar irradiance
The scattering channel of a spectroradiometer, as a commonly used optical parameter measuring device, can measure irradiance in all directions of the sky. To improve the calibration accuracy and efficiency, th...
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Decreased retinal vascular density is associated with cognitive impairment in CADASIL: an optical coherence tomography angiography study
This study aimed to assess alterations in retinal vascular density in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) patients using optical coherence tomog...
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Utilizing procalcitonin, C-reactive protein, and serum amyloid A in combination for diagnosing sepsis due to urinary tract infection
In this study, we aimed to evaluate the combined diagnostic value of procalcitonin (PCT), C-reactive protein (CRP), and serum amyloid A (SAA) in sepsis caused by urinary tract infection.
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Pt single atoms coupled with Ru nanoclusters enable robust hydrogen oxidation for high-performance anion exchange membrane fuel cells
The sluggish reaction kinetics of alkaline hydrogen oxidation reaction (HOR) is one of the key challenges for anion exchange membrane fuel cells (AEMFCs). To achieve robust alkaline HOR with minimized cost, we...
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Long-term survival outcomes of esophagectomy with off-pump CABG versus esophagectomy alone
This study aimed to evaluate the long-term survival outcomes of esophagectomy with off-pump coronary artery bypass grafting (OPCABG) vs. esophagectomy alone.
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Hydrogen Production from NaBH4 in a Mixed Water–Ethanol Solution Catalyzed by Co-W-Mo-B Catalyst
Co-B catalyst, W-modified Co-B (Co-W-B) catalyst, and Mo-modified Co-W-B (Co-W-Mo-B) catalyst powders were synthesized via chemical reduction of metal salt solutions at room temperature. The optimal hydrogen p...
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Open AccessGlobal variability in atmospheric new particle formation mechanisms
A key challenge in aerosol pollution studies and climate change assessment is to understand how atmospheric aerosol particles are initially formed1,2. Although new particle formation (NPF) mechanisms have been de...
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Open AccessYAP1 inhibits the senescence of alveolar epithelial cells by targeting Prdx3 to alleviate pulmonary fibrosis
The senescence of alveolar type II (AT2) cells impedes self-repair of the lung epithelium and contributes to lung injury in the setting of idiopathic pulmonary fibrosis (IPF). Yes-associated protein 1 (YAP1) i...
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Airways epithelial exposure to Streptococcus pneumoniae in the presence of the alarmin IL-33 induces a novel subset of pro-inflammatory ILC2s promoting a mixed inflammatory response
We have previously shown that asthma-like airways inflammation may be induced by topical exposure to respiratory tract pathogens such as S. pneumoniae (SP) in concert with epithelial alarmins such as IL-33. Detai...
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Open AccessNon-Abelian braiding of Fibonacci anyons with a superconducting processor
Quantum many-body systems with a non-Abelian topological order can host anyonic quasiparticles. It has been proposed that anyons could be used to encode and manipulate information in a topologically protected ...