24 Result(s)
within
Biomaterials
Biotechnology
Chemistry/Food Science, general
Immunology
Regenerative Medicine/Tissue Engineering
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Chapter
Life Sciences
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Chapter
Bioengineered Vascularized Insulin Producing Endocrine Tissues
Islet transplantation is a promising treatment for type 1 diabetes (T1D), but limited islet engraftment hampers its success. In vivo, islets require time to remodel the hepatic parenchyma and establish their o...
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Safety Issues Related to Pluripotent Stem Cell-Based Therapies: Tumour Risk
As the exciting era of regenerative medicine has dawned, considerable efforts aim to further develop human pluripotent stem cell (hPSC)-based therapies for a plethora of diseases, including diabetes mellitus. ...
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Minimal SC-β-Cell Properties for Transplantation in Diabetic Patients
Pancreatic β cells within the islets of Langerhans are the body’s main source for insulin. β cells maintain glucose homeostasis through the tight control of insulin secretion and cessation in response to chang...
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Modelling of Beta Cell Pathophysiology Using Stem Cell-Derived Islets
Diabetes mellitus is a family of metabolic disorders that arise from the loss or dysfunction of insulin secreting pancreatic beta cells. Many forms of early onset diabetes are caused by monogenic mutations in ...
