27,056 Result(s)
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Open AccessMulti-omic characterization of allele-specific regulatory variation in hybrid pigs
Hybrid map** is a powerful approach to efficiently identify and characterize genes regulated through mechanisms in cis. In this study, using reciprocal crosses of the phenotypically divergent Duroc and Lulai...
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Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587
Bedaquiline (BDQ), a first-in-class diarylquinoline anti-tuberculosis drug, and its analogue, TBAJ-587, prevent the growth and proliferation of Mycobacterium tuberculosis by inhibiting ATP synthase1,2. However, B...
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Evidence of striped electronic phases in a structurally modulated superlattice
The electronic properties of crystals can be manipulated by superimposing spatially periodic electric, magnetic or structural modulations. Long-wavelength modulations incommensurate with the atomic lattice are...
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Open AccessQuantification of cardiac capillarization in basement-membrane-immunostained myocardial slices using Segment Anything Model
Decreased myocardial capillary density has been reported as an important histopathological feature associated with various heart disorders. Quantitative assessment of cardiac capillarization typically involves...
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Open AccessReversible two-way tuning of thermal conductivity in an end-linked star-shaped thermoset
Polymeric thermal switches that can reversibly tune and significantly enhance their thermal conductivities are desirable for diverse applications in electronics, aerospace, automotives, and medicine; however, ...
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Open AccessMesoscale characterization of osseointegration around an additively manufactured genistein-coated implant
Given the hierarchical nature of bone and bone interfaces, osseointegration, namely the formation of a direct bone-implant contact, is best evaluated using a multiscale approach. However, a trade-off exists be...
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Open AccessAugmented reality navigation method based on image segmentation and sensor tracking registration technology
With the rapid development of modern science and technology, navigation technology provides great convenience for people's life, but the problem of inaccurate localization in complex environments has always be...
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Open AccessAnalysis of the multiple drivers of vegetation cover evolution in the Taihangshan-Yanshan region
The Taihangshan-Yanshan region (TYR) is an important ecological barrier area for Bei**g-Tian**-Hebei, and the effectiveness of its ecological restoration and protection is of great significance to the ecolog...
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Open AccessDynamics of polarization-tuned mirror symmetry breaking in a rotationally symmetric system
Lateral momentum conservation is typically kept in a non-absorptive rotationally symmetric system through mirror symmetry via Noether’s theorem when illuminated by a homogeneous light wave. Therefore, it is st...
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Open AccessA tabular data generation framework guided by downstream tasks optimization
Recently, generative models have been gradually emerging into the extended dataset field, showcasing their advantages. However, when it comes to generating tabular data, these models often fail to satisfy the ...
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Open AccessIntegrative proteome and metabolome unveil the central role of IAA alteration in axillary bud development following top** in tobacco
Axillary bud is an important aspect of plant morphology, contributing to the final tobacco yield. However, the mechanisms of axillary bud development in tobacco remain largely unknown. To investigate this aspe...
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Open AccessResearch on reliability map** of 5G low orbit constellation network slice based on deep reinforcement learning
Reliability map** of 5G low orbit constellation network slice is an important means to ensure link network communication. The problem of state space explosion is a typical problem. The deep reinforcement lea...
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Open AccessezSingleCell: an integrated one-stop single-cell and spatial omics analysis platform for bench scientists
ezSingleCell is an interactive and easy-to-use application for analysing various single-cell and spatial omics data types without requiring prior programing knowledge. It combines the best-performing publicly ...
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3D printable elastomers with exceptional strength and toughness
Three-dimensional (3D) printing has emerged as an attractive manufacturing technique because of its exceptional freedom in accessing geometrically complex customizable products. Its potential for mass manufact...
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Open AccessA unified model-based framework for doublet or multiplet detection in single-cell multiomics data
Droplet-based single-cell sequencing techniques rely on the fundamental assumption that each droplet encapsulates a single cell, enabling individual cell omics profiling. However, the inevitable issue of multi...
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Open AccessTamm-cavity terahertz detector
Efficiently fabricating a cavity that can achieve strong interactions between terahertz waves and matter would allow researchers to exploit the intrinsic properties due to the long wavelength in the terahertz ...
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Open AccessDevelopment and validation of an intraoperative hypothermia nomograph model for patients undergoing video-assisted thoracoscopic lobectomy: a retrospective study
This study aimed to develop and internally validate a nomogram model for assessing the risk of intraoperative hypothermia in patients undergoing video-assisted thoracoscopic (VATS) lobectomy. This study is a r...
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Open AccessLight-driven C–H activation mediated by 2D transition metal dichalcogenides
C–H bond activation enables the facile synthesis of new chemicals. While C–H activation in short-chain alkanes has been widely investigated, it remains largely unexplored for long-chain organic molecules. Here...
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Open AccessPassively harmonic dissipative soliton generation in normal dispersion erbium-doped fiber laser using SMS fiber as artificial saturable absorber
Passively harmonic mode-locking has been experimentally demonstrated in an erbium-doped fiber laser with large normal dispersion using single-multi-single mode structure as artificial saturable absorber. By in...
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Open AccessChromosome-level genome assembly of Helwingia omeiensis: the first genome in the family Helwingiaceae
Helwingia, a shrub of the monotypic cosmopolitan family Helwingiaceae, is distinguished by its inflorescence, in which flowers are borne on the midrib of the leaf—a trait not commonly observed in related plant fa...
