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  1. Article

    Open Access

    Administration of zoledronic acid alleviates osteoporosis in HIV patients by suppressing osteoclastogenesis via regulating RANKL expression

    Osteoporosis is a common phenomenon in HIV patients on tenofovir treatment, but its underlying mechanisms remain to be explored.

    Wei Lin, **ng-fu Li, Dong-cheng Ren, Meng Song, Li Duan, **-zhu Liu in Molecular Medicine (2021)

  2. Article

    Effectiveness of Lifestyle and Drug Intervention on Hypertensive Patients: a Randomized Community Intervention Trial in Rural China

    Strict medication guidance and lifestyle interventions to manage blood pressure (BP) in hypertensive patients are typically difficult to follow.

    **g **ao MD, PhD, Wen-Long Ren MD, PhD in Journal of General Internal Medicine (2020)

  3. Article

    Open Access

    Adipose-derived stromal cells modulating composite allotransplant survival is correlated with B cell regulation in a rodent hind-limb allotransplantation model

    Our previous studies demonstrated that adipose-derived mesenchymal stromal cells (ASCs) have immunomodulatory effects that prolong allograft survival in a rodent hind-limb allotransplant model. In this study, ...

    Chien-Chang Chen, Rong-Fu Chen, Jheng-Syuan Shao in Stem Cell Research & Therapy (2020)

  4. No Access

    Article

    Effect of Ultrasonic Vibration Tensile on the Mechanical Properties of High-Volume Fraction SiCp/Al Composite

    Silicon carbide particle-reinforced aluminum matrix composite has been widely used in the military and aerospace industry due to its special performance; however, there remain many problems in processing. The ...

    Dao-Hui **ang, Zhi-Meng Zhang, Bang-Fu Wu in International Journal of Precision Enginee… (2020)

  5. Article

    Open Access

    Long-term anti-inflammatory diet in relation to improved breast cancer prognosis: a prospective cohort study

    Inflammation-modulating nutrients and inflammatory markers are established cancer risk factors, however, evidence regarding the association between post-diagnosis diet-associated inflammation and breast cancer...

    Kang Wang, Jia-Zheng Sun, Qian-Xue Wu, Zhu-Yue Li, Da-Xue Li in npj Breast Cancer (2020)

  6. Article

    Antibody responses to SARS-CoV-2 in patients with COVID-19

    We report acute antibody responses to SARS-CoV-2 in 285 patients with COVID-19. Within 19 days after symptom onset, 100% of patients tested positive for antiviral immunoglobulin-G (IgG). Seroconversion for IgG...

    Quan-**n Long, Bai-Zhong Liu, Hai-Jun Deng, Gui-Cheng Wu, Kun Deng in Nature Medicine (2020)

  7. No Access

    Article

    Ascending Aortic Aneurysm After Repair of Aortico–Left Ventricular Tunnel

    Ascending aortic aneurysm following aortico–left ventricular tunnel (ALVT) repair is an uncommon but life-threatening complication. A 27-year-old man had received patch closure for ALVT at infancy. Eighteen ye...

    Hong-Jie Jhou, Liang-Ying Ke, Jiunn-Ren Wu, Ying-Fu Chen in Pediatric Cardiology (2020)

  8. No Access

    Article

    Hydrogen peroxide and nitric oxide are involved in programmed cell death induced by cryopreservation in Dendrobium protocorm-like bodies

    Programmed cell death (PCD) plays a key role in animal tissue cell death following cryopreservation. However, there are few studies evaluating the plant PCD characteristics induced by cryopreservation and the ...

    Xue-ru Jiang, Rui-fen Ren, Wei Di in Plant Cell, Tissue and Organ Culture (PCTO… (2019)

  9. No Access

    Article

    FMNL1 mediates nasopharyngeal carcinoma cell aggressiveness by epigenetically upregulating MTA1

    It has been suggested that formin-like protein 1 (FMNL1) plays an important role in the pathogenic process of several hematopoietic malignancies. In this study, we performed a series of in vivo and in vitro as...

    Wen-Hui Chen, Mu-Yan Cai, Jia-**ng Zhang, Feng-Wei Wang, Lin-Quan Tang in Oncogene (2018)

  10. Article

    Open Access

    A retrospective dosimetry study of intensity-modulated radiotherapy for nasopharyngeal carcinoma: radiation-induced brainstem injury and dose-volume analysis

    Radiation therapy is the standard radical treatment for nasopharyngeal carcinoma (NPC) but also causes transient as well as long-term complications. Patients who develop severe radiation-induced brainstem inju...

    Cheng-Yun Yao, Guo-Ren Zhou, Li-Jun Wang, Jian-Hua Xu, **-jun Ye in Radiation Oncology (2018)

  11. No Access

    Article

    The dark side of laparoscopic surgery for colorectal cancer patients aged 75 years or older

    The rate of postoperative morbidity and mortality is reportedly high in patients aged ≥ 75 years with colorectal cancer (CRC). In such patients, a comparison of the short-term outcome between open method and l...

    Yih-Jong Chern, Wen-Sy Tsai, Hsin-Yuan Hung in International Journal of Colorectal Disease (2018)

  12. No Access

    Article

    Oncoprotein Tudor-SN is a key determinant providing survival advantage under DNA damaging stress

    Herein, Tudor-SN was identified as a DNA damage response (DDR)-related protein that plays important roles in the early stage of DDR. X-ray or laser irradiation could evoke the accumulation of Tudor-SN to DNA d...

    **ao Fu, Chunyan Zhang, Hao Meng, Kai Zhang, Lei Shi in Cell Death & Differentiation (2018)

  13. Article

    Open Access

    Effect of eribulin on patients with metastatic breast cancer: multicenter retrospective observational study in Taiwan

    The aim of this study was to confirm the therapeutic role of eribulin on Taiwanese women with metastatic breast cancer.

    Kun-Ming Rau, Fu Ou-Yang, Ta-Chung Chao in Breast Cancer Research and Treatment (2018)

  14. No Access

    Article

    IR Spectra of Different O2-Content Hemoglobin from Computational Study: Promising Detector of Hemoglobin Variant in Medical Diagnosis

    IR spectra of heme and different O2-content hemoglobin were studied by the quantum computation method at the molecule level. IR spectra of heme and different O2-content hemoglobin were quantificationally characte...

    Su-qin Zhou, Tu-nan Chen, Guang-fu Ji in Interdisciplinary Sciences: Computational … (2017)

  15. Article

    Open Access

    31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two

    Casey Ager, Matthew Reilley, Courtney Nicholas in Journal for ImmunoTherapy of Cancer (2016)

  16. Article

    Open Access

    A lipasin/Angptl8 monoclonal antibody lowers mouse serum triglycerides involving increased postprandial activity of the cardiac lipoprotein lipase

    Lipasin/Angptl8 is a feeding-induced hepatokine that regulates triglyceride (TAG) metabolism; its therapeutical potential, mechanism of action and relation to the lipoprotein lipase (LPL), however, remain elus...

    Zhiyao Fu, Abdul B. Abou-Samra, Ren Zhang in Scientific Reports (2015)

  17. Article

    Open Access

    PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype

    PTEN is a tumour suppressor frequently mutated in many types of cancers. Here we show that targeted disruption of PTEN leads to neoplastic transformation of human neural stem cells (NSCs), but not mesenchymal ...

    Shunlei Duan, Guohong Yuan, **aomeng Liu, Ruotong Ren, **gyi Li in Nature Communications (2015)

  18. Article

    Open Access

    Ultralow threading dislocation density in GaN epilayer on near-strain-free GaN compliant buffer layer and its applications in hetero-epitaxial LEDs

    High threading dislocation (TD) density in GaN-based devices is a long unresolved problem because of the large lattice mismatch between GaN and the substrate, which causes a major obstacle for the further impr...

    Huan-Yu Shih, Makoto Shiojiri, Ching-Hsiang Chen, Sheng-Fu Yu in Scientific Reports (2015)

  19. No Access

    Article

    Myocardial protection of early extracorporeal membrane oxygenation (ECMO) support for acute myocardial infarction with cardiogenic shock in pigs

    The aim of this study was to explore myocardial protection of early extracorporeal membrane oxygenation (ECMO) support for acute myocardial infarction with cardiogenic shock in pigs. 24 male pigs (34.6 ± 1.3 k...

    Gang-jie Zhu, Li-na Sun, **ng-hai Li, Ning-fu Wang, Hong-hai Wu in Heart and Vessels (2015)

  20. Article

    Open Access

    The effects of acupuncture treatment on the right frontoparietal network in migraine without aura patients

    Functional and structural abnormalities in resting-state brain networks in migraine patients have been confirmed by previous functional magnetic resonance imaging (fMRI) studies. However, few studies focusing ...

    Kuangshi Li, Yong Zhang, Yanzhe Ning, Hua Zhang in The Journal of Headache and Pain (2015)

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