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31,007 Result(s)
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REDUCED HEART LIPID PEROXIDATION IN DILATED CARDIOMYOPATHY
Nitrofurantoin induced pulmonary fibroais may result from free radical(FR) production and subsequent lipid peroxidation(LPO). Furazolidone(FZ), a nitrofuran antibiotic, causes a dilated cardiomyopathy(CM) in t...
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ACETALDEHYDE INCREASES FREE IRON IN THE HEART: POSSIBLE MECHANISM IN ALCOHOL CAHDIOMYOPATHY
Chronic alcohol(ETOH) exposure in man and turkeys (TK) leads to structural and functional changes in the heart; similar cardiac pathology has been found in some infants with the fetal alcohol syndrome. The mec...
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Abstracts of papers Symposium “new therapeutic developments in human infectious diseases”
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Abstracts
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Laboratory and clinical diagnosis of human cytomegalovirus infection after transplantation
Urine and blood specimens from 32 recipients of allograft organ transplant were investigated for human cytomegalovirus (HCMV) by conventional cell culture, indirect immunofluo.rescent assay subsequent to the r...
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Sorbinil does not prevent galactose-induced glomerular capillary basement membrane thickening in the rat
We investigated the role of the polyol pathway in the pathogenesis of glomerular basement membrane thickening in galactosaemic rats, an animal model that develops basement membrane lesions comparable to those ...
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A non-mammalian in vivo model for cellular and molecular analysis of glucose-mediated thickening of basement membranes
An increase of basement membrane thickness in renal glomeruli, blood vessels, and other tissues is a consistent pathological observation in individuals with diabetes mellitus. Although a number of pathological...
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Isoforms of Mammalian Cytochrome c Oxidase:Correlation with Human Cytochrome c Oxidase Deficiency
ABSTRACT: We have reviewed the structure, function, and biogenesis of mammalian cytochrome c oxidase, examined the tissue-specific expression of isoforms of cytochrome c oxidase subunits in different mammals, ...
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Towards continuous glucose monitoring: in vivo evaluation of a miniaturized glucose sensor implanted for several days in rat subcutaneous tissue
A miniaturized amperometric, enzymatic, glucose sensor (outer diameter 0.45 mm) was evaluated after implantation in the subcutaneous tissue of normal rats. A simple experimental procedure was designed for the ...
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Islet amyloid polypeptide immunoreactivity in the human fetal pancreas
Islet amyloid polypeptide is known to localize to the adult human Beta cell. We analysed the immunoreactivity for islet amyloid polypeptide in a series of 29 human fetal pancreata (9–24 weeks of gestation) wit...
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Genotypic Confirmation from the Original Dried Blood Specimens in a Neonatal Hemoglobinopathy Screening Program
ABSTRACT: Dried blood spots are used for newborn screening because of ease of sample collection, handling, and shipment. DNA is stable and accessible in the filter paper matrix. Genotypic confirmation using in...
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Impaired visual evoked potential and primary axonopathy of the optic nerve in the diabetic BB/W-rat
The spontaneously diabetic BB/W-rat has emerged as an important model system for somatic and autonomic diabetic polyneuropathy. In this study we examined visual evoked potentials and the presence of morphometr...
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Infections II
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Miscellaneous III
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Shock I
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HOMOZYGOUS DELETION OF AMINO ACIDS 487–489 IN P450c17 CAUSES SEVERE 17α-HYDROXYLASE (17-OH) DEFICIENCY
17-OH and 17,20 lyase activities are mediated by cytochrome P450cl7. 17-OH deficiency is rare and only a few cases have been investigated at a molecular genetic level. A 14 y. o. female from rural Thailand was...
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Studies of Immunomodulating Actions of RNA/Nucleotides. RNA/Nucleotides Enhance In Vitro Immunoglobulin Production by Human Peripheral Blood Mononuclear Cells in Response to T-Dependent Stimuli
ABSTRACT: We have shown previously that yeast RNA preparations enhance in vitro antibody and Ig production to T-dependent antigens in normal B6 mice. In this study, Ig production by human peripheral blood mononuc...
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Abstract
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A glucose monitoring system for on line estimation in man of blood glucose concentration using a miniaturized glucose sensor implanted in the subcutaneous tissue and a wearable control unit
We have developed a miniaturized glucose sensor which has been shown previously to function adequately when implanted in the subcutaneous tissue of rats and dogs. Following a glucose load, the sensor output in...
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Alloxan cytotoxicity is highly potentiated by plasma membrane- and lysosomal-associated iron — a study on a model system of cultured J-774 cells
Pancreatic islet beta cells, and some other cell types, are sensitive to the damaging effects of alloxan. The mechanisms behind the cytotoxicity have not been fully elucidated, although they are considered to ...