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Application of Air-Assisted Liquid-Liquid Microextraction for Determination of Some Fluoroquinolones in Milk Powder and Egg Samples: Comparison with Conventional Dispersive Liquid-Liquid Microextraction

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Abstract

Herein, an air-assisted liquid-liquid microextraction (AALLME) has been described and compared to conventional dispersive liquid-liquid microextraction (DLLME) for the extraction/preconcentration of six fluoroquinolone compounds in milk powder and egg samples prior to high-performance liquid chromatography-UV detection (HPLC-UV). In order to compare the novel AALLME technique to the conventional DLLME technique, several parameters that influence the extraction efficiency were studied and optimized. Both methods have been validated for milk powder and egg analysis, obtaining limits of quantification lower than those usually permitted by legislation in food matrices, with precisions expressed as coefficients of variation lower than 8 % and recoveries between 72 and 115 % which were acceptable recoveries and repeatability. An AALLME method needs less organic solvent and shorter centrifugation time; therefore, it is more environmentally friendly and efficiently compared to DLLME.

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Acknowledgments

This work was financially supported by the Nature Science Foundation of China (No. 21005033), Nature Science Foundation of Jiangsu Province (Nos. BK2011242 and BK20140577), College Education Nature Science Foundation of Jiangsu (No. 10KJD350001), and Advanced Talents Science Foundation of Jiangsu University (No. 10JDG052).

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Authors and Affiliations

  1. Department of Pharmaceutics, School of Pharmacy, Jiangsu University, Zhenjiang, 212013, China

    Li Wang, Ting Huang, Hai **a Cao & Zhong ** Liang

  2. Department of Environment Science, School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang, 212013, China

    Qiu **ang Yuan & Guo ** Liang

Authors
  1. Li Wang
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  2. Ting Huang
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  3. Hai **a Cao
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  4. Qiu **ang Yuan
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  5. Zhong ** Liang
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  6. Guo ** Liang
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Correspondence to Li Wang or Guo ** Liang.

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Li Wang declares that she has no conflict of interest. Ting Huang declares that she has no conflict of interest. Hai **a Cao declares that she has no conflict of interest. Qiu **ang Yuan declares that she has no conflict of interest. Zhong ** Liang declares that she has no conflict of interest. Guo ** Liang declares that he has no conflict of interest.

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Wang, L., Huang, T., Cao, H.X. et al. Application of Air-Assisted Liquid-Liquid Microextraction for Determination of Some Fluoroquinolones in Milk Powder and Egg Samples: Comparison with Conventional Dispersive Liquid-Liquid Microextraction. Food Anal. Methods 9, 2223–2230 (2016). https://doi.org/10.1007/s12161-016-0409-6

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  • DOI: https://doi.org/10.1007/s12161-016-0409-6

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