Collection
Advancing Methods in Molecular Biology and Genetics
The techniques we use to investigate the universe around us are essential for the advancement of science. Novel, methods can open whole new fields of study, while refinements to a protocol can dramatically improve its efficiency, accuracy and reliability of results. Such advancements have the greatest impact when shared and incorporated across research communities.
This collection, the first of a series at BMC Research Notes, seeks to showcase the myriad of improvements and additions to research techniques used across Molecular Biology and Genetics. We welcome Research Note articles addressing:
· Methods to improve sample or data quality
· Methods that improve reliability and accuracy
· Faster methods
· More powerful methods
· Method comparisons
and Commentaries discussing:
· The history and future of significant techniques or methods in molecular biology and genetics
· New or scientifically challenging techniques and their potential
· Controversial methods or models and their impact
Articles (26 in this collection)
-
-
Simultaneous assessment of mitochondrial DNA copy number and nuclear epigenetic age towards predictive models of development and aging
Authors (first, second and last of 7)
-
The speed-gene study: methods, study design and preliminary results
Authors (first, second and last of 7)
-
A novel tetra-primer ARMS-PCR for genoty** of the OPRM1 gene rs1799971 variant associated with opioid use disorders
Authors (first, second and last of 6)
-
Genome sequence of a virulent and hypermucoviscous-like Klebsiella michiganensis clinical isolate
Authors (first, second and last of 7)
-
Assessment of MYC and TERT copy number variations in lung cancer using digital PCR
Authors (first, second and last of 12)
-
The effect of glatiramer acetate, IFNβ-1a, fingolimod, and dimethyl fumarate on the expression of T-bet, IFN-γ, and MEG3 in PBMC of RRMS patients
Authors (first, second and last of 7)
-
Sustain release of dexamethasone from polyvinyl alcohol microparticle produced via coaxial microfluidic system
Authors (first, second and last of 4)
-
Genomic, transcriptomic and epigenomic sequencing data of the B-cell leukemia cell line REH
Authors (first, second and last of 21)
-
Targeted sequencing of selected functional genes in patients with wild-type transthyretin amyloidosis
Authors (first, second and last of 8)
-
In vivo direct cell-penetrating peptide mediated protein transduction system in Acyrthosiphon pisum
Authors
-
-
A hybrid RNA FISH immunofluorescence protocol on Drosophila polytene chromosomes
Authors (first, second and last of 4)
-
-
Deriving GWAS summary estimates for paternal smoking in UK biobank: a GWAS by subtraction
Authors (first, second and last of 4)
-
The UK BiLEVE and Mendelian randomisation: using multivariable instrumental variables to address “damned if you, damned if you don’t” adjustment problems
Authors (first, second and last of 4)
-
GeneXpert MTB/RIF Ultra performance to detect uncommon rpoB mutations in Mycobacterium tuberculosis
Authors (first, second and last of 6)
-
A quick, easy and efficient protocol for extracting high-quality RNA from Mycobacterium tuberculosis using a spin column commercial kit
Authors (first, second and last of 6)
-
Evaluation of rRNA depletion methods for capturing the RNA virome from environmental surfaces
Authors (first, second and last of 6)
-
Topology and adenocarcinoma cell localization dataset on the labyrinthin diapeutic biomarker
Authors (first, second and last of 4)
-
In-silico molecular designs to treat neurologic and ophthalmologic diseases caused by sorbitol excess: engineering the Agrobacterium vitis protein
Authors (first, second and last of 5)
-
-
In vitro anti-Toxoplasma gondii activity of Ganoderma lucidum extracts
Authors (first, second and last of 9)
-
Construction of high coverage whole-genome sequencing libraries from single colon crypts without DNA extraction or whole-genome amplification
Authors (first, second and last of 7)
-
Particle bombardment-assisted peptide-mediated gene transfer for highly efficient transient assay
Authors (first, second and last of 4)
-
