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Fragile Sites

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Human Chromosome Variation: Heteromorphism, Polymorphism and Pathogenesis

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Abstract

According to Sutherland and Hecht [1], fragility at specific sites on chromosomes was first described by Dekeban in 1965 and by Lejeune et al. in 1968.

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Author information

Authors and Affiliations

  1. Genesys Diagnostics, Inc., Oakdale, CT, USA

    Herman E. Wyandt

  2. Department of Pediatrics, Texas Tech University Health Sciences Center, Lubbock, TX, USA

    Golder N. Wilson

  3. Department of Pediatrics, Texas Tech University Health Sciences Center, Lubbock, TX, USA

    Vijay S. Tonk

Authors
  1. Herman E. Wyandt
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  2. Golder N. Wilson
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  3. Vijay S. Tonk
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Correspondence to Herman E. Wyandt .

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Wyandt, H.E., Wilson, G.N., Tonk, V.S. (2017). Fragile Sites. In: Human Chromosome Variation: Heteromorphism, Polymorphism and Pathogenesis. Springer, Singapore. https://doi.org/10.1007/978-981-10-3035-2_7

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