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Finite Element Analysis of Transcatheter Aortic Valve Implantation in the Presence of Aortic Leaflet Calcifications

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Biomedical Technology

Part of the book series: Lecture Notes in Applied and Computational Mechanics ((LNACM,volume 74))

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Abstract

Transcatheter Aortic Valve (TAV) implantation is a recent interventional procedure for the replacement of the aortic valve in patients affected by severe aortic stenosis who are considered at high or prohibitive surgical risk. Despite recent improvements, TAV-related complications still limit its application. In the present work, FE analyses of TAV implantation and function have been performed with the aim of investigating the influence of the calcifications of the aortic valve leaflets on TAV performances. Results suggest that the degree and location of calcifications could influence post-implanted TAV configuration as well as TAV-aortic root interactions and TAV dynamics. The study gives insights in the biomechanics of TAV, while the implemented computational tools could be applied to different scenarios to investigate other relevant clinical aspects.

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Author information

Authors and Affiliations

  1. Department of Electronics, Information and Bioengineering, Politecnico di Milano, Milano, Italy

    Annalisa Dimasi, Marco Stevanella, Emiliano Votta, Francesco Sturla & Alberto Redaelli

  2. Division of Cardiovascular Surgery, Università degli Studi di Verona, Verona, Italy

    Francesco Sturla

  3. Department of Mechanical Engineering, University College of London, London, UK

    Gaetano Burriesci

Authors
  1. Annalisa Dimasi
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  2. Marco Stevanella
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  3. Emiliano Votta
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  4. Francesco Sturla
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  5. Gaetano Burriesci
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  6. Alberto Redaelli
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Corresponding author

Correspondence to Annalisa Dimasi .

Editor information

Editors and Affiliations

  1. Department of Otorhinolaryngology, Hannover Medical School, Hannover, Germany

    Thomas Lenarz

  2. Institute of Continuum Mechanics, Leibniz Universität Hannover, Hannover, Germany

    Peter Wriggers

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Dimasi, A., Stevanella, M., Votta, E., Sturla, F., Burriesci, G., Redaelli, A. (2015). Finite Element Analysis of Transcatheter Aortic Valve Implantation in the Presence of Aortic Leaflet Calcifications. In: Lenarz, T., Wriggers, P. (eds) Biomedical Technology. Lecture Notes in Applied and Computational Mechanics, vol 74. Springer, Cham. https://doi.org/10.1007/978-3-319-10981-7_7

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  • DOI: https://doi.org/10.1007/978-3-319-10981-7_7

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-10980-0

  • Online ISBN: 978-3-319-10981-7

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