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Jackfruit Seed Starch-Based Composite Beads for Controlled Drug Release

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Polymeric and Natural Composites

Part of the book series: Advances in Material Research and Technology ((AMRT))

Abstract

Jackfruit (Artocarpus heterophyllus Lam.; family: Moraceae) seed starch (JSS) is a natural starch candidate, which is already reported as a potential pharmaceutical biopolymeric raw materials/excipients in various pharmaceutical dosage forms, such as binding agent and disintegrants in pharmaceutical tablets, emulsifier in emulsions, suspending agent in suspensions, and mucoadhesive agent in biomucoadhesive dosage forms. Recent years, JSS has been utilized to prepare controlled drug-releasing composite beads, when processed with other biopolymers like sodium alginate, gellan gum, and low methoxy pectin. All these JSS-based composite beads demonstrated in vitro controlled releasing of encapsulated drugs over a longer time and significant in vivo hypoglycemic actions in the treated alloxan-induced diabetic Albino rats over prolonged time interval after administration through oral route. The current chapter presents a comprehensive review of various JSS-based composite beads for controlled sustained releasing of encapsulated drugs.

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Authors and Affiliations

  1. Department of Pharmaceutics, Seemanta Institute of Pharmaceutical Sciences, 757086, Mayurbhanj, Odisha, India

    Amit Kumar Nayak

  2. Department of Zoology, College of Science, King Saud University, 2455, 11451, Riyadh, Saudi Arabia

    Saad Alkahtani

  3. Department of Pharmacy, Palamau Institute of Pharmacy, Chianki, 822102, Daltonganj, Jharkhand, India

    Md Saquib Hasnain

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  1. Amit Kumar Nayak
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Editors and Affiliations

  1. Department of Pharmacy, Palamau Institute of Pharmacy, Daltonganj, Jharkhand, India

    Md Saquib Hasnain

  2. Department of Pharmaceutics, Seemanta Institute of Pharmaceutical Sciences, Mayurbhanj, Odisha, India

    Amit Kumar Nayak

  3. Department of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia

    Saad Alkahtani

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Nayak, A.K., Alkahtani, S., Hasnain, M.S. (2022). Jackfruit Seed Starch-Based Composite Beads for Controlled Drug Release. In: Hasnain, M.S., Nayak, A.K., Alkahtani, S. (eds) Polymeric and Natural Composites. Advances in Material Research and Technology. Springer, Cham. https://doi.org/10.1007/978-3-030-70266-3_7

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