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Sterculia Gum-Based Hydrogels for Drug Delivery Applications

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Polymeric Hydrogels as Smart Biomaterials

Part of the book series: Springer Series on Polymer and Composite Materials ((SSPCM))

Abstract

Sterculia gum is one of the medicinally important plant-derived water soluble polysaccharides obtained from the exudate of the tree, Sterculia urens (Family: sterculiaceae). It is recognized as a promising biodegradable material in the development of various biomedical applications including drug delivery applications, wound dressing applications, etc. Sterculia gum is also employed as excipient in the designing of various pharmaceutical applications. In recent years, several attempts for the modification of sterculia gum have been undertaken to develop sterculia gum-based hydrogels for controlling the rate of hydration and swelling, and also tailoring the release profile of various types of drugs. In the development of these sterculia gum-based hydrogels, modifications of sterculia gum through polymer blending, cross-linking, interpenetrated polymer network (IPN) formation, polymer grafting, etc., were investigated for improved drug delivery applications. Most of these already reported sterculia gum-based hydrogels were found effective for gastroretentive deliveries as wound dressings for sustained release of various drugs. The current chapter deals with a comprehensive and useful discussion on already investigated sterculia gum-based hydrogels for the use in drug delivery applications, where the first portion of the chapter contains source, composition, and properties of sterculia gum and the latter portion contains discussion on the formulations of various sterculia gum-based hydrogel systems used for various types of drug delivery applications.

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Authors and Affiliations

  1. Department of Pharmaceutics, Seemanta Institute of Pharmaceutical Sciences, Mayurbhanj, Odisha, 757086, India

    Amit Kumar Nayak

  2. Department of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya, Koni, Bilaspur, Chhattisgarh, 495009, India

    Dilipkumar Pal

Authors
  1. Amit Kumar Nayak
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  2. Dilipkumar Pal
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Correspondence to Amit Kumar Nayak .

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Editors and Affiliations

  1. Department of Chemistry, ACC Wing, Indian Military Academy, Dehradun, Uttarakhand, India

    Susheel Kalia

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Nayak, A.K., Pal, D. (2016). Sterculia Gum-Based Hydrogels for Drug Delivery Applications. In: Kalia, S. (eds) Polymeric Hydrogels as Smart Biomaterials. Springer Series on Polymer and Composite Materials. Springer, Cham. https://doi.org/10.1007/978-3-319-25322-0_5

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