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Sodium, Calcium, and Neurogenic Factors in the Pathogenesis of Essential Hypertension

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Contemporary Nephrology

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Abstract

In recent years a great deal of interest has been focused on the role of sodium and calcium in the pathogenesis of hypertension. Whereas the evidence linking sodium ingestion to the genesis of hypertension in both humans and experimental animals is sufficiently convincing, serious doubts still remain as to whether abnormalities of calcium metabolism are important and, more specifically, whether reduced calcium intake and/or increased urinary calcium loss is important in the genesis of hypertension.

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Authors and Affiliations

  1. Division of Nephrology, LAC/USC Medical Center, Los Angeles, California, 90033, USA

    Vito M. Campese

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  1. Washington University School of Medicine, St. Louis, Missouri, USA

    Saulo Klahr M.D.

  2. University of Southern California School of Medicine, Los Angeles, California, USA

    Shaul G. Massry M.D.

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Campese, V.M. (1989). Sodium, Calcium, and Neurogenic Factors in the Pathogenesis of Essential Hypertension. In: Klahr, S., Massry, S.G. (eds) Contemporary Nephrology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0829-4_6

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