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Screening of Antimicrobial Residues in Muscle fromDifferent Species by Liquid Chromatography Coupled with Tandem Mass Spectrometry

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Chemical Food Contaminants Analysis

Part of the book series: Methods and Protocols in Food Science ((MPFS))

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Abstract

A screening methodology for the analysis of 46 antimicrobial (ATB) residues has been developed and validated for application in muscle samples obtained from various animal species, including bovine, swine, poultry, equine, shrimp, and fish. This method utilizes liquid chromatography coupled with mass spectrometry using both low-resolution and high-resolution systems (LC-MS/MS and LC-QTOF, respectively). Analytical scope includes a diverse range of ATBs, including tetracyclines, sulfonamides, fluoroquinolones, beta-lactams, cephalosporins, macrolides, and other minor groups. Samples were extracted using solid-liquid extraction, followed by cleanup procedures based on dispersive solid-phase extraction (d-SPE) and low-temperature purification (LTP).

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Authors and Affiliations

  1. Laboratório Federal de Defesa Agropecuária no Rio Grande do Sul (LFDA-RS), Ministério da Agricultura e Pecuária, Porto Alegre, RS, Brazil

    Louise Jank, Magda Targa Martins, Tamara dos Santos Castilhos & Fabiano Barreto

Authors
  1. Louise Jank
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  2. Magda Targa Martins
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  3. Tamara dos Santos Castilhos
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  4. Fabiano Barreto
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Corresponding author

Correspondence to Louise Jank .

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Editors and Affiliations

  1. Ministry of Agriculture, Livestock, and, Sao Jose, Brazil

    Rodrigo Hoff

  2. Ministry of Agriculture Livestock and Su, Federal Distsrict, Brazil

    Luciano Molognoni

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© 2024 The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature

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Jank, L., Martins, M.T., dos Santos Castilhos, T., Barreto, F. (2024). Screening of Antimicrobial Residues in Muscle fromDifferent Species by Liquid Chromatography Coupled with Tandem Mass Spectrometry. In: Hoff, R., Molognoni, L. (eds) Chemical Food Contaminants Analysis. Methods and Protocols in Food Science . Humana, New York, NY. https://doi.org/10.1007/978-1-0716-3806-4_7

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  • DOI: https://doi.org/10.1007/978-1-0716-3806-4_7

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-3805-7

  • Online ISBN: 978-1-0716-3806-4

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