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Artificial Intelligence in Vaccine and Drug Design

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Vaccine Design

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2410))

Abstract

Knowledge in the fields of biochemistry, structural biology, immunological principles, microbiology, and genomics has all increased dramatically in recent years. There has also been tremendous growth in the fields of data science, informatics, and artificial intelligence needed to handle this immense data flow. At the intersection of wet lab and data science is the field of bioinformatics, which seeks to apply computational tools to better understanding of the biological sciences. Like so many other areas of biology, bioinformatics has transformed immunology research leading to the discipline of immunoinformatics. Within this field, many new databases and computational tools have been created that increasingly drive immunology research, in many cases drawing upon artificial intelligence and machine learning to predict complex immune system behaviors, for example, prediction of B cell and T cell epitopes. In this book chapter, we provide an overview of computational tools and artificial intelligence being used for protein modeling, drug screening, vaccine design, and highlight how these tools are being used to transform approaches to pandemic countermeasure development, by reference to the current COVID-19 pandemic.

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Authors and Affiliations

  1. Lankenau Institute for Medical Research, Wynnewood, PA, USA

    Sunil Thomas & Ann Abraham

  2. Vaxine Pty Ltd, Adelaide, SA, Australia

    Jeremy Baldwin, Sakshi Piplani & Nikolai Petrovsky

  3. College of Medicine and Public Health, Flinders University, Adelaide, SA, Australia

    Sakshi Piplani & Nikolai Petrovsky

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  1. Sunil Thomas
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  2. Ann Abraham
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  3. Jeremy Baldwin
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  4. Sakshi Piplani
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  5. Nikolai Petrovsky
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Editors and Affiliations

  1. Lankenau Institute for Medical Research, Wynnewood, PA, USA

    Sunil Thomas

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Thomas, S., Abraham, A., Baldwin, J., Piplani, S., Petrovsky, N. (2022). Artificial Intelligence in Vaccine and Drug Design. In: Thomas, S. (eds) Vaccine Design. Methods in Molecular Biology, vol 2410. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1884-4_6

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  • DOI: https://doi.org/10.1007/978-1-0716-1884-4_6

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-1883-7

  • Online ISBN: 978-1-0716-1884-4

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