Extended Data Fig. 9: Female mice are protected from obesity.
From: Interaction between the gut microbiota and colonic enteroendocrine cells regulates host metabolism
(a) Weight curves of female WT and EECΔCol animals with HFD starting at 18 weeks of life (n = 6 mice). (b) PCoA of ß-diversity by unweighed UNIFRAC of 6–8 week old male (n = 14 mice) and female (n = 14 WT or 15 EECΔCol mice). PERMANOVA p = 0.001. (c) Volcano plot of differential abundance testing of fecal microbiota species (sequence variants) from WT and EECΔCol male and female mice at 6–8 weeks of age. (d) Volcano plot of differential abundance testing in different genders of EECΔCol mice. Only statistically significant features are shaded in color. Mean values and error bars representing ± s.e.m. are shown. Two-tailed unpaired t-test used for all pairwise comparisons.