Log in

Data science in healthcare: techniques, challenges and opportunities

  • Review Paper
  • Published:
Health and Technology Aims and scope Submit manuscript

Abstract

Purpose

Integrating data science techniques in healthcare has emerged as a transformative force and holds immense potential for improving patient outcomes, enhancing operational efficiency, and advancing medical research by utilizing medical information. This paper aims to explore various data science techniques employed in the field of healthcare, highlight corresponding challenges, and identify opportunities for innovation.

Methods

A comprehensive literature review was conducted to gather insight into the current use to data science applications in healthcare domain. We explored various databases like Google Scholar, PubMed, IEEE Xplore using relevant keywords such as “data science”, “data science in healthcare”, “data science techniques”, “data science applications in healthcare”, “Machine Learning in healthcare”, and “Predictive Analytics”. We focused on papers published between 2015 and 2023.

Results

Data Science techniques including Artificial Intelligence, Machine Learning, Deep Learning, Natural Language Processing, etc. are being used for tasks such as disease prediction, personalized treatment recommendation, medical imaging analysis, and healthcare resource optimization. Nonetheless, challenges such as data privacy, quality, data access and ethics in using healthcare data were identified as barriers in their extensive implementation.

Conclusions

Important insights that could improve patient outcomes and lower healthcare expenditures can be obtained by employing data science techniques on data generated through wearable technology, medical imaging, Electronic Health Records (EHR), etc. To fully utilize data science in healthcare, however, data quality, privacy, and security issues must be resolved, and deliberative frameworks must be created to enable the use of data science in healthcare in an ethical and responsible manner.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

Data availability statement

As this is a review paper, there are no new datasets generated or analysed during the current study.

References

  1. Syed L, Jabeen S, Manimala S, Elsayed HA. Data science algorithms and techniques for smart healthcare using iot and big data analytics. Stud Fuzziness Soft Comput. 2019;374:211–41. https://doi.org/10.1007/978-3-030-03131-2_11/COVER.

    Article  Google Scholar 

  2. Cao L. Data Science. ACM Computing Surveys (CSUR). 2017. https://doi.org/10.1145/3076253.

    Article  Google Scholar 

  3. Grossi V, Giannotti F, Pedreschi D, Manghi P, Pagano P, Assante M. Data science: a game changer for science and innovation. Int J Data Sci Anal. 2021;11(4):263–78. https://doi.org/10.1007/S41060-020-00240-2/FIGURES/6.

    Article  Google Scholar 

  4. Wing JM. Ten Research Challenge Areas in Data Science. Harv Data Sci Rev. 2020. https://doi.org/10.1162/99608f92.c6577b1f.

    Article  Google Scholar 

  5. Subrahmanya SVG, et al. The role of data science in healthcare advancements: applications, benefits, and future prospects. Ir J Med Sci. 2022;191(4):1473–83. https://doi.org/10.1007/S11845-021-02730-Z/FIGURES/5.

    Article  Google Scholar 

  6. Parida PK, Dora L, Swain M, Agrawal S, Panda R. Data science methodologies in smart healthcare: a review. Heal Technol. 2022;12(2):329–44. https://doi.org/10.1007/S12553-022-00648-9.

    Article  Google Scholar 

  7. Liang Y, Kelemen A. Big Data Science and Its Applications in Health and Medical Research: Challenges and Opportunities. J Biom Biostat. 2016. https://doi.org/10.4172/2155-6180.1000307.

    Article  Google Scholar 

  8. Kim SH, Kim NU, Chung TM. Attribute Relationship Evaluation Methodology for Big Data Security. In 2013 International Conference on IT Convergence and Security (ICITCS). IEEE. 2013. p. 1–4. https://doi.org/10.1109/ICITCS.2013.6717808.

  9. Abedjan Z, et al. Data science in healthcare: Benefits, challenges and opportunities. Springer International Publishing; 2019. p. 3–38. https://doi.org/10.1007/978-3-030-05249-2_1/COVER.

  10. Alloghani M, Al-Jumeily D, Mustafina J, Hussain A, Aljaaf AJ. A Systematic Review on Supervised and Unsupervised Machine Learning Algorithms for Data Science. Supervised and unsupervised learning for data science. 2020. p. 3–21. https://doi.org/10.1007/978-3-030-22475-2_1.

  11. Abouelmehdi K, Beni-Hessane A, Khaloufi H. Big healthcare data: preserving security and privacy. J Big Data. 2018;5(1):1–18. https://doi.org/10.1186/S40537-017-0110-7/TABLES/5.

    Article  Google Scholar 

  12. Egger R, Neuburger L, Mattuzzi M. Data science and ethical issues: between knowledge gain and ethical responsibility. In: Applied Data Science in Tourism: Interdisciplinary Approaches, Methodologies, and Applications. Cham: Springer International Publishing; 2022. p. 51–66. https://doi.org/10.1007/978-3-030-88389-8_4.

    Chapter  Google Scholar 

  13. Saltz JS, Dewar N. Data science ethical considerations: a systematic literature review and proposed project framework. Ethics Inf Technol. 2019;21(3):197–208. https://doi.org/10.1007/S10676-019-09502-5/TABLES/5.

    Article  Google Scholar 

  14. Khaloufi H, Abouelmehdi K, Beni-Hssane A, Saadi M. Security model for Big Healthcare Data Lifecycle. Procedia Comput Sci. 2018;141:294–301. https://doi.org/10.1016/J.PROCS.2018.10.199.

    Article  Google Scholar 

  15. Mehrtak M, et al. Security challenges and solutions using healthcare cloud computing. J Med Life. 2021;14(4):448. https://doi.org/10.25122/JML-2021-0100.

    Article  Google Scholar 

  16. Ottenbacher KJ, Graham JE, Fisher SR. Data Science in Physical Medicine and Rehabilitation: Opportunities and Challenges. Phys Med Rehabil Clin. 2019;30(2):459–71. https://doi.org/10.1016/j.pmr.2018.12.003.

    Article  Google Scholar 

  17. Shortreed SM, Cook AJ, Coley RY, Bobb JF, Nelson JC. Challenges and Opportunities for Using Big Health Care Data to Advance Medical Science and Public Health. Am J Epidemiol. 2019;188(5):851–61. https://doi.org/10.1093/AJE/KWY292.

    Article  Google Scholar 

  18. Rudrapatna VA, Butte AJ. Opportunities and challenges in using real-world data for health care. J Clin Investig. 2020;130(2):565–74. https://doi.org/10.1172/JCI129197.

    Article  Google Scholar 

  19. Waring J, Lindvall C, Umeton R. Automated machine learning: Review of the state-of-the-art and opportunities for healthcare. Artif Intell Med. 2020;104: 101822. https://doi.org/10.1016/J.ARTMED.2020.101822.

    Article  Google Scholar 

  20. Sanchez-Pinto LN, Luo Y, Churpek MM. Big Data and Data Science in Critical Care. Chest. 2018;154(5):1239–48. https://doi.org/10.1016/J.CHEST.2018.04.037.

    Article  Google Scholar 

  21. Koleck TA, Dreisbach C, Bourne PE, Bakken S. Natural language processing of symptoms documented in free-text narratives of electronic health records: a systematic review. J Am Med Inform Assoc. 2019;26(4):364–79. https://doi.org/10.1093/JAMIA/OCY173.

    Article  Google Scholar 

  22. Arowosegbe A, Oyelade T. Application of Natural Language Processing (NLP) in Detecting and Preventing Suicide Ideation: A Systematic Review. Int J Environ Res Public Health. 2023;20(2):1514. https://doi.org/10.3390/IJERPH20021514.

    Article  Google Scholar 

  23. Diab KM, Deng J, Wu Y, Yesha Y, Collado-Mesa F, Nguyen P. Natural Language Processing for Breast Imaging: A Systematic Review. Diagnostics. 2023;13(8):1420. https://doi.org/10.3390/DIAGNOSTICS13081420.

    Article  Google Scholar 

  24. Khurana D, Koli A, Khatter K, Singh S. Natural language processing: state of the art, current trends and challenges. Multimed Tools Appl. 2023;82(3):3713–44. https://doi.org/10.1007/S11042-022-13428-4/FIGURES/3.

    Article  Google Scholar 

  25. Leung CK. Data Science for Big Data Applications and Services: Data Lake Management, Data Analytics and Visualization. In: Big Data Analyses, Services, and Smart Data 6, vol. 899. Singapore: Springer; 2021. p. 28–44. https://doi.org/10.1007/978-981-15-8731-3_3/COVER.

    Chapter  Google Scholar 

  26. Paul O, Rajput NS, Dehury C. Computer Vision in COVID-19: A Study. Impact of AI and Data Science in Response to Coronavirus Pandemic. 2021. p. 285–304. https://doi.org/10.1007/978-981-16-2786-6_14.

  27. Kumar S, Singh M. Big data analytics for healthcare industry: Impact, applications, and tools. Big Data Min Anal. 2019;2(1):48–57. https://doi.org/10.26599/BDMA.2018.9020031.

    Article  Google Scholar 

  28. Batko K, Ślęzak A. The use of Big Data Analytics in healthcare. J Big Data. 2022;9(1):1–24. https://doi.org/10.1186/S40537-021-00553-4/TABLES/11.

    Article  Google Scholar 

  29. Kumar M, et al. Healthcare Internet of Things (H-IoT): Current Trends, Future Prospects, Applications, Challenges, and Security Issues. Electronics. 2023;12(9):20500. https://doi.org/10.3390/ELECTRONICS12092050.

    Article  Google Scholar 

  30. Rehman A, Naz S, Razzak I. Leveraging big data analytics in healthcare enhancement: trends, challenges and opportunities. Multimed Syst. 2021;28(4):1339–71. https://doi.org/10.1007/S00530-020-00736-8.

    Article  Google Scholar 

  31. Dalianis H, Henriksson A, Kvist M, Velupillai S, Weegar R. HEALTH BANK-A Workbench for Data Science Applications in Healthcare. CAiSE Industry Track. 2015;1381:1–18. Available: https://www.i2b2.org/NLP/HeartDisease/PreviousChallenges.php.

  32. Jayaratne M, et al. A data integration platform for patient-centered e-healthcare and clinical decision support. Futur Gener Comput Syst. 2019;92:996–1008. https://doi.org/10.1016/J.FUTURE.2018.07.061.

    Article  Google Scholar 

  33. Ali O, Abdelbaki W, Shrestha A, Elbasi E, Alryalat MAA, Dwivedi YK. A systematic literature review of artificial intelligence in the healthcare sector: Benefits, challenges, methodologies, and functionalities. J Innov Knowl. 2023;8(1): 100333. https://doi.org/10.1016/J.JIK.2023.100333.

    Article  Google Scholar 

  34. Joshi I, et al. Artificial intelligence, big data and machine learning approaches in genome-wide SNP-based prediction for precision medicine and drug discovery. Big Data Analytics in Chemoinformatics and Bioinformatics. 2023. p. 333–357. https://doi.org/10.1016/B978-0-323-85713-0.00021-9.

  35. Asri H, Mousannif H, Al Moatassime H, Noel T. Big data in healthcare: Challenges and opportunities. In 2015 International Conference on Cloud Technologies and Applications (CloudTech), IEEE. 2015;1:1–7. https://doi.org/10.1109/CloudTech.2015.7337020.

  36. Muniasamy A, Tabassam S, Hussain MA, Sultana H, Muniasamy V, Bhatnagar R. Deep Learning for Predictive Analytics in Healthcare. In: The International Conference on Advanced Machine Learning Technologies and Applications (AMLTA2019) 4. Springer International Publishing; 2020. p. 32–42. https://doi.org/10.1007/978-3-030-14118-9_4.

    Chapter  Google Scholar 

  37. Malasinghe LP, Ramzan N, Dahal K. Remote patient monitoring: a comprehensive study. J Ambient Intell Humaniz Comput. 2019;10(1):57–76. https://doi.org/10.1007/S12652-017-0598-X/TABLES/6.

    Article  Google Scholar 

  38. Razzak MI, Imran M, Xu G. Big data analytics for preventive medicine. Neural Comput Appl. 2020;32(9):4417–51. https://doi.org/10.1007/S00521-019-04095-Y/FIGURES/5.

    Article  Google Scholar 

  39. Krishna CV, Rohit HR, Mohana. A review of artificial intelligence methods for data science and data analytics: Applications and research challenges. Proceedings of the International Conference on I-SMAC (IoT in Social, Mobile, Analytics and Cloud), I-SMAC 2018. 2019. p. 591–594. https://doi.org/10.1109/I-SMAC.2018.8653670.

  40. Gruson D, Helleputte T, Rousseau P, Gruson D. Data science, artificial intelligence, and machine learning: Opportunities for laboratory medicine and the value of positive regulation. Clin Biochem. 2019;69:1–7. https://doi.org/10.1016/J.CLINBIOCHEM.2019.04.013.

    Article  Google Scholar 

  41. McCoy LG, Banja JD, Ghassemi M, Celi LA. Ensuring machine learning for healthcare works for all. BMJ Health Care Inform. 2020;27(3):100237. https://doi.org/10.1136/BMJHCI-2020-100237

    Article  Google Scholar 

  42. Bloice MD, Holzinger A. A Tutorial on Machine Learning and Data Science Tools with Python. Machine Learning for Health Informatics: State-of-the-Art and Future Challenges. 2016. p. 435–480. https://doi.org/10.1007/978-3-319-50478-0_22.

  43. Alanazi A. Using machine learning for healthcare challenges and opportunities. Inform Med Unlocked. 2022;30:100924. https://doi.org/10.1016/J.IMU.2022.100924.

    Article  Google Scholar 

  44. Keskinbora KH. Medical ethics considerations on artificial intelligence. J Clin Neurosci. 2019;64:277–82. https://doi.org/10.1016/J.JOCN.2019.03.001.

    Article  Google Scholar 

  45. Chen IY, Pierson E, Rose S, Joshi S, Ferryman K, Ghassemi M. Ethical Machine Learning in Healthcare. Annu Rev Biomed Data Sci. 2021;4:123–44. https://doi.org/10.1146/annurev-biodatasci-092820-114757.

    Article  Google Scholar 

  46. Baldi P. Deep Learning in Biomedical Data Science. Annu Rev Biomed Data Sci. 2018;1(1):181–205. https://doi.org/10.1146/annurev-biodatasci-080917-013343.

    Article  MathSciNet  Google Scholar 

  47. Alzubaidi L, et al. Review of deep learning: concepts, CNN architectures, challenges, applications, future directions. J Big Data. 2021;8(1):1–74. https://doi.org/10.1186/S40537-021-00444-8.

    Article  Google Scholar 

  48. Bansal A, Sharma R, Kathuria M. A Systematic Review on Data Scarcity Problem in Deep Learning: Solution and Applications. ACM Comput Surv. 2022. https://doi.org/10.1145/3502287.

    Article  Google Scholar 

  49. Singh K, Malhotra D. Meta-Health: Learning-to-Learn (Meta-learning) as a Next Generation of Deep Learning Exploring Healthcare Challenges and Solutions for Rare Disorders: A Systematic Analysis. Arch Comput Methods Eng. 2023;30(7):4081–112. https://doi.org/10.1007/S11831-023-09927-8/FIGURES/6.

    Article  Google Scholar 

  50. Kaul D, Raju H, Tripathy BK. Deep Learning in Healthcare. Deep Learning in Data Analytics: Recent Techniques, Practices and Applications. 2022;91:97–115. https://doi.org/10.1007/978-3-030-75855-4_6/COVER.

  51. Miotto R, Wang F, Wang S, Jiang X, Dudley JT. Deep learning for healthcare: review, opportunities and challenges. Brief Bioinform. 2018;19(6):1236–46. https://doi.org/10.1093/BIB/BBX044.

    Article  Google Scholar 

  52. Vaci N, et al. Natural language processing for structuring clinical text data on depression using UK-CRIS. BMJ Ment Health. 2020;23(1):21–6. https://doi.org/10.1136/EBMENTAL-2019-300134.

    Article  Google Scholar 

  53. Vinod Vydiswaran VG, Zhao X, Yu D. Data Science and Natural Language Processing to Extract Information in Clinical Domain. In Proceedings of the 5th Joint International Conference on Data Science & Management of Data (9th ACM IKDD CODS and 27th COMAD). 2022. pp. 352–353. https://doi.org/10.1145/3493700.3493773.

  54. Alibasic A, Simsekler MCE, Kurfess T, Woon WL, Omar MA. Utilizing data science techniques to analyze skill and demand changes in healthcare occupations: case study on USA and UAE healthcare sector. Soft Comput. 2020;24(7):4959–76. https://doi.org/10.1007/S00500-019-04247-1/FIGURES/19.

    Article  Google Scholar 

  55. Bala I. Natural Language Processing in Medical Science and Healthcare. Medicon Med Sci. 2022;4(1):1–2. https://doi.org/10.55162/mcms.04.088.

    Article  Google Scholar 

  56. Safdari R, Rezayi S, Saeedi S, Tanhapour M, Gholamzadeh M. Using data mining techniques to fight and control epidemics: A sco** review. Heal Technol. 2021;11(4):759–71. https://doi.org/10.1007/S12553-021-00553-7/TABLES/4.

    Article  Google Scholar 

  57. Leung CK, et al. Data science for healthcare predictive analytics. In Proceedings of the 24th Symposium on International Database Engineering & Applications. 2020. pp. 1–10. https://doi.org/10.1145/3410566.3410598.

  58. Hirve SA, Kunjir A, Shaikh B, Shah K. An approach towards data visualization based on AR principles. Proceedings of the 2017 International Conference On Big Data Analytics and Computational Intelligence, ICBDACI IEEE. 2017. pp. 128–133. https://doi.org/10.1109/ICBDACI.2017.8070822.

  59. Comba JLD. Data Visualization for the Understanding of COVID-19. Comput Sci Eng. 2020;22(6):81–6. https://doi.org/10.1109/MCSE.2020.3019834.

    Article  Google Scholar 

  60. Agrawal R, Kadadi A, Dai X, Andres F. Challenges and opportunities with big data visualization. In Proceedings of the th International Conference on Management of computational and collective intElligence in Digital EcoSystems. New York, NY, USA: ACM. 2015. pp. 169–173. https://doi.org/10.1145/2857218.2857256.

  61. Padmapriya ST, Parthasarathy S. Ethical Data Collection for Medical Image Analysis: a Structured Approach. Asian Bioeth Rev. 2024;16(1):95–108. https://doi.org/10.1007/S41649-023-00250-9.

    Article  Google Scholar 

  62. Kushwah S, Das S. Sentiment Analysis of Big-Data in Healthcare: Issue and Challenges. In 2020 IEEE 5th International Conference on Computing Communication and Automation (ICCCA) IEEE. 2020. pp. 658–663. https://doi.org/10.1109/ICCCA49541.2020.9250841.

  63. Vij A, Pruthi J. An automated Psychometric Analyzer based on Sentiment Analysis and Emotion Recognition for healthcare. Procedia Comput Sci. 2018;132:1184–91. https://doi.org/10.1016/J.PROCS.2018.05.033.

    Article  Google Scholar 

  64. Abualigah L, Alfar HE, Shehab M, Hussein AMA. Sentiment Analysis in Healthcare: A Brief Review. Stud Comput Intell. 2020;874:129–41. https://doi.org/10.1007/978-3-030-34614-0_7.

    Article  Google Scholar 

  65. Gao J, Yang Y, Lin P, Park DS. Computer Vision in Healthcare Applications”. J Healthc Eng. 2018. https://doi.org/10.1155/2018/5157020.

    Article  Google Scholar 

  66. Kennedy-Metz LR, et al. Computer Vision in the Operating Room: Opportunities and Caveats. IEEE Trans Med Robot Bionics. 2021;3(1):2–10. https://doi.org/10.1109/TMRB.2020.3040002.

    Article  Google Scholar 

  67. Khan B, et al. Drawbacks of Artificial Intelligence and Their Potential Solutions in the Healthcare Sector. Biomedical Mater Devices. 2023;1(2):731–8. https://doi.org/10.1007/S44174-023-00063-2/METRICS.

    Article  Google Scholar 

  68. Holzinger A, et al. AI for life: Trends in artificial intelligence for biotechnology. New Biotechnol. 2023;74:16–24. https://doi.org/10.1016/J.NBT.2023.02.001.

    Article  Google Scholar 

  69. Nithya B, Ilango V. Predictive analytics in health care using machine learning tools and techniques. In 2017 International Conference on Intelligent Computing and Control Systems (ICICCS) IEEE. 2017. https://doi.org/10.1109/ICCONS.2017.8250771.

    Article  Google Scholar 

  70. Ramgopal S, Sanchez-Pinto LN, Horvat CM, Carroll MS, Luo Y, Florin TA. Artificial intelligence-based clinical decision support in pediatrics. Pediatr Res. 2022;93(2):334–41. https://doi.org/10.1038/s41390-022-02226-1.

    Article  Google Scholar 

  71. Rasheed K, Qayyum A, Ghaly M, Al-Fuqaha A, Razi A, Qadir J. Explainable, trustworthy, and ethical machine learning for healthcare: A survey. Comput Biol Med. 2022;149: 106043. https://doi.org/10.1016/J.COMPBIOMED.2022.106043.

    Article  Google Scholar 

  72. Albahri AS, et al. A systematic review of trustworthy and explainable artificial intelligence in healthcare: Assessment of quality, bias risk, and data fusion. Inform Fusion. 2023;96:156–91. https://doi.org/10.1016/J.INFFUS.2023.03.008.

    Article  Google Scholar 

  73. El-Sappagh S, Alonso-Moral JM, Abuhmed T, Ali F, Bugarín-Diz A. Trustworthy artificial intelligence in Alzheimer’s disease: state of the art, opportunities, and challenges. Artif Intell Rev. 2023. https://doi.org/10.1007/S10462-023-10415-5.

    Article  Google Scholar 

  74. Pandey B, Kumar Pandey D, Pratap Mishra B, Rhmann W. A comprehensive survey of deep learning in the field of medical imaging and medical natural language processing: Challenges and research directions. J King Saud Univ Comput Inf Sci. 2022;34(8):5083–99. https://doi.org/10.1016/J.JKSUCI.2021.01.007.

    Article  Google Scholar 

  75. Shorten C, Khoshgoftaar TM, Furht B. Deep Learning applications for COVID-19. J Big Data. 2021;8(1):1–54. https://doi.org/10.1186/S40537-020-00392-9.

    Article  Google Scholar 

  76. Weese J, Lorenz C. Four challenges in medical image analysis from an industrial perspective. Med Image Anal. 2016;33:44–9. https://doi.org/10.1016/J.MEDIA.2016.06.023.

    Article  Google Scholar 

  77. Esteva A, et al. Deep learning-enabled medical computer vision. NPJ Digit Med. 2021;4(1):1–9. https://doi.org/10.1038/s41746-020-00376-2.

    Article  Google Scholar 

  78. Haghi Kashani M, Madanipour M, Nikravan M, Asghari P, Mahdipour E. A systematic review of IoT in healthcare: Applications, techniques, and trends. J Netw Comput Appl. 2021;192:103164. https://doi.org/10.1016/J.JNCA.2021.103164.

    Article  Google Scholar 

  79. https://www.youtube.com/watch?v=ua-CiDNNj30. Accessed 4 Dec 2023.

Download references

Funding

The research presented in this manuscript received no specific funding from any agency, organization, or institution.

Author information

Authors and Affiliations

Authors

Contributions

The work described in this manuscript was conducted collaboratively. Pushpa Devi, as a Ph.D. scholar, conducted the primary research, while Professor Kishori Lal Bansal provided guidance and supervision throughout the project.

Corresponding author

Correspondence to Pushpa Devi.

Ethics declarations

Ethical approval

Not Applicable.

Consent to participate

Not Applicable.

Consent to publish

Not Applicable.

Conflict of interest

The authors declare no conflict of interest that could have influenced the research presented in this manuscript.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Devi, P., Bansal, K.L. Data science in healthcare: techniques, challenges and opportunities. Health Technol. 14, 623–634 (2024). https://doi.org/10.1007/s12553-024-00861-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12553-024-00861-8

Keywords

Navigation