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Three-dimensional perfusion imaging of hepatocellular carcinoma using 256-slice multidetector-row computed tomography

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Abstract

Purpose

The aim of this study was to evaluate the clinical capability of three-dimensional (3D) perfusion imaging of hepatocellular carcinoma (HCC) by performing dynamic scanning using a 256-slice multidetector-row CT (MDCT) scanner.

Materials and methods

Two patients with HCC were examined in this study. They were scheduled to undergo transcatheter arterial infusion therapy using an arterial infusion reservoir system. The CT system used was a newly developed prototype scanner of 256-slice MDCT. Dynamic CT scanning was performed with intraarterial injection via the reservoir route, and perfusion analysis was done based on the 3D data.

Results

The blood flow volume per unit volume in the tumors was significantly increased compared with that in normal hepatic parenchyma. Using a 3D workstation, 3D perfusion images could be displayed by fusing CT images with perfusion images about blood flow volume.

Conclusion

Three-dimensional perfusion images, which enable 3D evaluation of perfusion in HCCs, can be generated using 256-slice MDCT.

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Author information

Authors and Affiliations

  1. Division of Radiology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, 277-8577, Japan

    Tatsushi Kobayashi & Takayuki Hayashi

  2. CT Systems Development Department, Toshiba Medical Systems Corporation, Otawara, Japan

    Shintaro Funabasama & Shinsuke Tsukagoshi

  3. Department of Radiology, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Japan

    Manabu Minami

  4. Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan

    Noriyuki Moriyama

Authors
  1. Tatsushi Kobayashi
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  2. Takayuki Hayashi
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  3. Shintaro Funabasama
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  4. Shinsuke Tsukagoshi
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  5. Manabu Minami
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  6. Noriyuki Moriyama
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Corresponding author

Correspondence to Tatsushi Kobayashi.

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Kobayashi, T., Hayashi, T., Funabasama, S. et al. Three-dimensional perfusion imaging of hepatocellular carcinoma using 256-slice multidetector-row computed tomography. Radiat Med 26, 557–561 (2008). https://doi.org/10.1007/s11604-008-0266-3

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  • DOI: https://doi.org/10.1007/s11604-008-0266-3

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