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Acute effects of high-intensity interval training and moderate-intensity continuous training on left ventricular function in women with uncomplicated obesity

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Abstract

Purpose

Obesity is associated with subclinical impairments in cardiac function. Aerobic exercise has positive effects on cardiac-related parameters. However, different exercise intensities may elicit distinct acute responses, leading to chronic adaptations. Therefore, we aimed to investigate the acute effects of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on left ventricle (LV) function in women with uncomplicated obesity.

Methods

Fifteen women performed a bout of HIIT (4 × 4-min at 85–95% of HRmax), MICT (41-min at 65–75% of HRmax), and control condition (CO) (30-min sitting at rest). Data were collected immediately before, and five (t5) and 35 (t35) minutes after the performance of each condition.

Results

Significant decreases in global longitudinal strain (GLS) (p = 0.010; p = 0.002), LV ejection fraction (LVEF) (p = 0.017; p = 0.010), LV end-diastolic volume (LVEDV) (p = 0.001; p = 0.048), stroke volume (SV) (p < 0.001; p = 0.013), early diastolic inflow velocity (E) (p = 0.001; p = 0.003) and E/A ratio (p = 0.001; p < 0.001) were observed for HIIT at t5 in relation to baseline and CO, respectively. However, GLS, LVEF, LVEDV, and E wave were reestablished near baseline values at t35. LV end-systolic volume decreased after HIIT in comparison to baseline at t5 (p = 0.050). GLS and E/A ratio decreased following HIIT at t5 compared to MICT (p = 0.013 and p = 0.027, respectively).

Conclusion

A single bout of HIIT promoted transient reductions in LV function that were almost completely reestablished near baseline values 35 min after exercise cessation, not implying, therefore, any risk to HIIT performance by this population.

Trial registration number

RBR-3v3dqf (Registered on 07/05/2019).

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Data availability

Raw data will be available under request.

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Acknowledgements

The current study was funded by the Fundação Araucária de Apoio ao Desenvolvimento Científico e Tecnológico do Estado do Paraná (FA) (CP 20/18 PPP), Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) and Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES). We would like to thank the Avancor employees for their assistance during the assessments.

Funding

Fundacao Araucaria, CP 20/18 PPP.

Author information

Authors and Affiliations

  1. School of Human Sciences (Sport Science, Exercise and Health), The University of Western Australia, 28 Stirling Highway, Perth, WA, 6009, Australia

    João Carlos Locatelli

  2. Research Group on Systemic Arterial Hypertension, Arterial Stiffness and Vascular Aging (GPHARV), Maringa, Parana, Brazil

    Caroline Ferraz Simões, Higor Barbosa Reck, Gustavo Henrique de Oliveira, Victor Hugo de Souza Mendes, Rogério Toshiro Passos Okawa & Wendell Arthur Lopes

  3. Estacio do Amazonas College, Manaus, Amazonas, Brazil

    Caroline Ferraz Simões

  4. Department of Physical Education, Center of Health Sciences, State University of Maringa, Maringa, Parana, Brazil

    Higor Barbosa Reck, Gustavo Henrique de Oliveira & Wendell Arthur Lopes

  5. Research Institute for Sports and Exercise Science, Liverpool John Moores University, Liverpool, UK

    David Oxborough

  6. Department of Medicine, Center of Health Sciences, State University of Maringa, Maringa, Parana, Brazil

    Rogério Toshiro Passos Okawa

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  1. João Carlos Locatelli
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Contributions

J.C.L.: Methodology, Investigation, Data curation, Writing—Original Draft, Writing—Review & Editing, Visualization. C.F.S.: Methodology, Formal analysis, Data curation, Writing—Review & Editing. H.B.R.: Formal analysis, Data curation, Writing—Review & Editing. G.H.O: Methodology, Formal analysis, Data curation, Writing—Review & Editing. V.H.S.M.: Methodology, Writing—Review & Editing. D.O.: Data curation, Visualization, Writing—Review & Editing. R.T.P.O.: Conceptualization, Methodology, Investigation, Resources, Writing—Review & Editing, Visualization, Supervision, Project administration. W.A.L.: Conceptualization, Methodology, Validation, Formal analysis, Investigation, Resources, Data Curation, Writing—Original Draft, Writing—Review & Editing, Visualization, Supervision, Project administration, Funding acquisition. All authors reviewed the manuscript.

Corresponding author

Correspondence to João Carlos Locatelli.

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Conflicts of interest

The authors declare that they have no competing interests.

Ethical approval and informed consent

This study was approved by the local ethics committee (Comitê Permanente de Ética em Pesquisa com Seres Humanos–COPEP. Protocol number: 91380218.4.0000.0104) and registered as a clinical trial on the Brazilian Clinical Trials Registry (RBR-3v3dqf). Informed consent was obtained prior to the beginning of the assessments. In addition, the present study is in accordance with the 1964 Declaration of Helsinki and its later amendments, rigorously following the requirements settled on Resolution 466/2012 of the Brazilian National Health Council.

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Locatelli, J.C., Simões, C.F., Reck, H.B. et al. Acute effects of high-intensity interval training and moderate-intensity continuous training on left ventricular function in women with uncomplicated obesity. Sport Sci Health (2024). https://doi.org/10.1007/s11332-024-01193-w

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