Abstract
This paper estimates the effect of the OxyContin reformulation and the subsequent heroin crisis on grandparent caregiving in the United States—grandparents who are primarily responsible for their grandchildren. The empirical approach is a difference-in-differences and a series of event studies that exploit variation in the timing of the reformulation of OxyContin and geographic variation in pre-reformulation rates of nonmedical use of OxyContin across states. I find that a standard deviation increase in pre-reformulation nonmedical use of OxyContin leads to higher grandparent caregiving. Increases range from 2.5 to 8.5%, on average, relative to the baseline mean. This change is more pronounced among grandparents between 46 and 65 years of age. When I examine changes in heroin-related mortality as a possible mechanism, I find modest increases in grandparent caregiving when no parents are present or when no or only one parent is present of 1.80 and 1.50% of the baseline mean, on average.
![](http://media.springernature.com/m312/springer-static/image/art%3A10.1007%2Fs11113-024-09870-x/MediaObjects/11113_2024_9870_Fig1_HTML.png)
![](http://media.springernature.com/m312/springer-static/image/art%3A10.1007%2Fs11113-024-09870-x/MediaObjects/11113_2024_9870_Fig2_HTML.png)
![](http://media.springernature.com/m312/springer-static/image/art%3A10.1007%2Fs11113-024-09870-x/MediaObjects/11113_2024_9870_Fig3_HTML.png)
![](http://media.springernature.com/m312/springer-static/image/art%3A10.1007%2Fs11113-024-09870-x/MediaObjects/11113_2024_9870_Fig4_HTML.png)
![](http://media.springernature.com/m312/springer-static/image/art%3A10.1007%2Fs11113-024-09870-x/MediaObjects/11113_2024_9870_Fig5_HTML.png)
Similar content being viewed by others
Data availability
All data used in this project is publicly available. Access to detailed mortality files can be obtained from the National Center for Health Statistics. The replication package for all analyses is available from the author.
Notes
For more information on OxyContin see: Center for Substance Abuse Treatment (2008). OxyContin®: Prescription Drug Abuse—2008 Revision. Substance Abuse Treatment Advisory, Volume 7, Issue 1. Rockville, MD: Substance Abuse and Mental Health Services Administration.
I thank David Powell who facilitated these data. It is also available on Alpert et al. (2018) replication package.
The correlation between heroin-related death rates and deaths due to prescription opioids is 0.34. The correlation between heroin-related deaths and illicit fatal overdoses due to synthetic opioids is 0.68.
All results in tabular form are in Appendix Tables A10, A11, and A12.
On average, the age of grandparents who are responsible for grandchildren in my sample is 56.3.
Note that, the number of grandparents in the 30 to 45 age and 66 years old or more categories is small (7,086 and 4,945 on average respectively). In the other two groups the average is above 17,000.
Results available from the author.
Results available from the author.
Results available from the author.
References
Alpert, A., Powell, D., & Pacula, R. L. (2018). Supply-side drug policy in the presence of substitutes: Evidence from the introduction of abuse-deterrent opioids. American Economic Journal: Economic Policy, 10(4), 1–35. https://doi.org/10.1257/pol.20170082
Arndt, S., Clayton, R., & Schultz, S. K. (2011). Trends in substance abuse treatment 1998–2008: Increasing older adult first-time admissions for illicit drugs. The American Journal of Geriatric Psychiatry, 19(8), 704–711. https://doi.org/10.1097/JGP.0b013e31820d942b
Beheshti, D. (2019). Adverse health effects of abuse-deterrent opioids: Evidence from the reformulation of OxyContin. Health Economics, 28(12), 1449–1461. https://doi.org/10.1002/hec.3944
Beltran, A. (2017). Grandparents raising the children of the opioid epidemic. Child Law Practice, 36, 100.
Brant, K. (2022). When Mamaw becomes mom: Social capital and kinship family formation amid the rural opioid crisis. RSF: the Russell Sage Foundation Journal of the Social Sciences, 8(3), 78–98. https://doi.org/10.7758/RSF.2022.8.3.03
Buckles, K., Evans, W. N., & Lieber, E. M. J. (2023). The drug crisis and the living arrangements of children. Journal of Health Economics, 87, 102723. https://doi.org/10.1016/j.jhealeco.2022.102723
Caudillo, M. L., & Villarreal, A. (2021). The opioid epidemic and nonmarital childbearing in the United States, 2000–2016. Demography, 58(1), 345–378. https://doi.org/10.1215/00703370-8937348
Caudillo, M. L., Villarreal, A., & Cohen, P. N. (2021). The opioid epidemic and children’s living arrangements in the United States, 2000–2018. SocAr**v. https://doi.org/10.31235/osf.io/he4pb
Ciccarone, D. (2019). The triple wave epidemic: Supply and demand drivers of the US opioid overdose crisis. International Journal of Drug Policy, 71, 183–188. https://doi.org/10.1016/j.drugpo.2019.01.010
Cicero, T. J., & Ellis, M. S. (2015). Abuse-deterrent formulations and the prescription opioid abuse epidemic in the United States: Lessons learned from OxyContin. JAMA Psychiatry, 72(5), 424–430. https://doi.org/10.1001/jamapsychiatry.2014.3043
Davis, M. T., Warfield, M. E., Boguslaw, J., Roundtree-Swain, D., & Kellogg, G. (2020). Parenting a 6-year old is not what I planned in retirement: Trauma and stress among grandparents due to the opioid crisis. Journal of Gerontological Social Work, 63(4), 295–315. https://doi.org/10.1080/01634372.2020.1752872
DeRigne, L., & Ferrante, S. (2012). The sandwich generation: A review of the literature. The Sandwich Generation, 9.
Ellis, R. R., & Simmons, T. (2014). Coresident grandparents and their grandchildren: 2012. Journal of Societal and Social Policy, 7, 53.
Evans, W. N., Lieber, E. M. J., & Power, P. (2019). How the reformulation of OxyContin ignited the heroin epidemic. The Review of Economics and Statistics, 101(1), 1–15. https://doi.org/10.1162/rest_a_00755
Huang, X., Keyes, K. M., & Li, G. (2018). Increasing prescription opioid and heroin overdose mortality in the United States, 1999–2014: An age–period–cohort analysis. American Journal of Public Health, 108(1), 131–136. https://doi.org/10.2105/AJPH.2017.304142
Jones, C. M., Logan, J., Gladden, R. M., & Bohm, M. K. (2015). Vital signs: Demographic and substance use trends among heroin users—United States, 2002–2013. Morbidity and Mortality Weekly Report, 64(26), 719–725.
Kelley, S. J. (1993). Caregiver stress in grandparents raising grandchildren. Image: the Journal of Nursing Scholarship, 25(4), 331–337. https://doi.org/10.1111/j.1547-5069.1993.tb00268.x
Kennedy-Hendricks, A., Richey, M., McGinty, E. E., Stuart, E. A., Barry, C. L., and Webster, D. W. (2016). Opioid overdose deaths and Florida’s crackdown on pill mills. American Journal of Public Health, 106(2):291–297.
Letiecq, B. L., Bailey, S. J., & Porterfield, F. (2008). “We Have No Rights, We Get No Help”: The legal and policy dilemmas facing grandparent caregivers. Journal of Family Issues, 29(8), 995–1012. https://doi.org/10.1177/0192513X08316545
Mackenzie-Liu, M. (2021). From fostering hope to lingering harm: The unintended impact of the OxyContin reformulation on child welfare utilization. Social Service Review, 95(1), 36–65. https://doi.org/10.1086/713378
Meinhofer, A., & Angleró-Díaz, Y. (2019). Trends in foster care entry among children removed from their homes because of parental drug use, 2000 to 2017. JAMA Pediatrics, 173(9), 881–883. https://doi.org/10.1001/jamapediatrics.2019.1738
Park, S., & Powell, D. (2021). Is the rise in illicit opioids affecting labor supply and disability claiming rates? Journal of Health Economics, 76, 102430. https://doi.org/10.1016/j.jhealeco.2021.102430
Pilkauskas, N. V., Amorim, M., & Dunifon, R. E. (2020). Historical trends in children living in multigenerational households in the United States: 1870–2018. Demography, 57(6), 2269–2296. https://doi.org/10.1007/s13524-020-00920-5
Pilkauskas, N. V., & Cross, C. (2018). Beyond the nuclear family: Trends in children living in shared households. Demography, 55(6), 2283–2297. https://doi.org/10.1007/s13524-018-0719-y
Powell, D., Alpert, A., & Pacula, R. L. (2019). A transitioning epidemic: How the opioid crisis is driving the rise in hepatitis C. Health Affairs, 38(2), 287–294. https://doi.org/10.1377/hlthaff.2018.05232
Powell, D., & Pacula, R. L. (2021). The evolving consequences of OxyContin reformulation on drug overdoses. American Journal of Health Economics, 7(1), 41–67. https://doi.org/10.1086/711723
Quast, T., Storch, E. A., & Yampolskaya, S. (2018). Opioid prescription rates and child removals: Evidence from Florida. Health Affairs, 37(1), 134–139. https://doi.org/10.1377/hlthaff.2017.1023
Raitasalo, K., & Holmila, M. (2017). Parental substance abuse and risks to children’s safety, health and psychological development. Drugs: Education, Prevention and Policy, 24(1), 17–22. https://doi.org/10.1080/09687637.2016.1232371
Ruggles, S., Fitch, C. A., Goeken, R., Hacker, J. D., Nelson, M. A., Roberts, E., Schouweiler, M., & Sobek, M. (2021). IPUMS ancestry full count data: Version 3.0. University of Minnesota.
Smith, V. C., Wilson, C. R., Committee on Substance Use and Prevention, Ryan, S. A., Gonzalez, P. K., Patrick, S. W., Quigley, J., Siqueira, L., & Walker, L. R. (2016). Families affected by parental substance use. Pediatrics, 138(2), e20161575. https://doi.org/10.1542/peds.2016-1575
Taylor, M. F., Marquis, R., Coall, D. A., Batten, R., & Werner, J. (2017). The physical health dilemmas facing custodial grandparent caregivers: Policy considerations. Cogent Medicine, 4(1), 1292594. https://doi.org/10.1080/2331205X.2017.1292594
Warren, E. C., & Kolodny, A. (2021). Trends in heroin treatment admissions in the United States by race, sex, and age. JAMA Network Open, 4(2), e2036640. https://doi.org/10.1001/jamanetworkopen.2020.36640
Acknowledgements
I gratefully acknowledge the support of the University of Illinois Chicago through its awards for creative activity. I thank Damien Dong and Alexis Davila for their excellent research assistance at various stages of this project. I also thank two anonymous reviewers for their helpful comments and feedback.
Author information
Authors and Affiliations
Corresponding author
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Supplementary Information
Below is the link to the electronic supplementary material.
Rights and permissions
Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
About this article
Cite this article
Laurito, A. Spillovers of the Heroin Epidemic on Grandparent Caregiving. Popul Res Policy Rev 43, 25 (2024). https://doi.org/10.1007/s11113-024-09870-x
Received:
Accepted:
Published:
DOI: https://doi.org/10.1007/s11113-024-09870-x