The effect of the eluent composition (type and concentration of the organic and acid components) on the retention times and selectivity of the separation of some standard samples of phenylpropanoids under reversed- phase HPLC conditions is studied. Ethanol, being a nontoxic solvent, exhibited good characteristics as an eluent for the separation of this group of substances. A mobile phase containing ethanol and organic acids could be recommended as an extractant for studies of plant raw material containing phenylpropanoids.
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 58, No. 1, pp. 61 – 64, January, 2024.
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Abramov, O.K., Ryabukha, A.F. & Pletneva, I.V. Change in Chromatographic Parameters of Some Phenylpropanoids in Different Mobile Phases Under Reversed-Phase HPLC Conditions. Pharm Chem J 58, 138–141 (2024). https://doi.org/10.1007/s11094-024-03128-8
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DOI: https://doi.org/10.1007/s11094-024-03128-8