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Improvement of physical properties of poly(glycerol sebacate) by copolymerization with polyhydroxybutyrate-diols

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Abstract

The characterizations and physical properties of elastomeric poly(glycerol sebacate) (PGS) copolymerized with different amounts of polyhydroxybutyrate diol (PHB-diol) were analyzed with 1H-NMR, differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), mechanical test, biodegradation test, and cytotoxicity analysis. The chemical composition of the PHB-diol prepared and the copolymerization reaction of the PHB-diol in the PGS were confirmed by 1H-NMR. From 1H-NMR analysis, the PHB-diol prepared had the molecular weight about 989.6 g/mol and a faster crystallization rate than the PHB according to the DSC measurement. The tensile/compressive strengths of PGS-co-(PHB-diol) increased while the crosslinking densities decreased with the amount of PHB-diol copolymerized. The PGS-co-(PHB-diol) had a slower biodegradation rate but a worse thermal stability than the PGS. Additionally, the biodegradable PGS-co-(PHB-diol) elastomers prepared exhibited no cytotoxicity and could replace PGS used in bio-fields.

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Authors and Affiliations

  1. Department of Chemical Engineering and Materials Science, Yuan-Ze University, Tao-Yuan, 320, Taiwan

    Bo-Chen Tang, Chao-Ling Yao, Ku-Yu **eh & Shinn-Gwo Hong

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  1. Bo-Chen Tang
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  2. Chao-Ling Yao
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  3. Ku-Yu **eh
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  4. Shinn-Gwo Hong
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Correspondence to Shinn-Gwo Hong.

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This article is part of the Topical Collection on Bio-Based Polymers

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Tang, BC., Yao, CL., **eh, KY. et al. Improvement of physical properties of poly(glycerol sebacate) by copolymerization with polyhydroxybutyrate-diols. J Polym Res 24, 215 (2017). https://doi.org/10.1007/s10965-017-1371-8

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  • DOI: https://doi.org/10.1007/s10965-017-1371-8

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