Abstract
Despite demonstrated efficacy of behavioral and cognitive techniques in treating the impact of tinnitus (constant ringing in the ears), little is known about the mechanisms by which these techniques achieve their effect. The present study examined acceptance of tinnitus as a potential mediator of treatment changes on global tinnitus severity in internet-delivered acceptance and commitment therapy (iACT) and internet-delivered cognitive behavior therapy (iCBT). Data from 67 participants who were distressed by tinnitus and who were randomly assigned to 1 of the 2 treatments were analyzed using a multilevel moderated mediation model. We predicted that acceptance as measured with the two subscales of the tinnitus acceptance questionnaire (i.e., activity engagement and tinnitus suppression) would mediate the outcome in iACT, but not in iCBT. Results provided partial support to the notion that mediation was moderated by treatment: tinnitus suppression mediated changes in tinnitus severity in iACT, but not in iCBT. However, inconsistent with the view that the treatments worked through different processes of change, activity engagement mediated treatment changes across both iACT and iCBT. Acceptance is identified as a key source of therapeutic change in behavioral-based treatments for tinnitus.
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Notes
Linear time was estimated for several reasons. First, in many situations, especially when the time period is short or when the number of measurement points is few, a linear model can provide a good approximation of complex growth processes (Raudenbush and Bryk 2002). Second, to our knowledge, little is currently known about how the estimated combined multivariate model of mediation performs when non-linear associations are estimated in terms of, for example, accuracy of estimates and SE. Third, and most important, despite the fact that there was room for improvement, linear models provided a reasonable fit to the observed data (fit indices for linear models can be provided upon request from the first author).
We also considered models in which we allowed the effect of the time-varying predictor, TAQ, on the outcome, THI, to vary across individuals (i.e., random effect of the b j coefficient). Kenny et al. (2003) have suggested to included the covariance of a and b paths in lower level multilevel models in the computation of the standard error of the ab-product. However, as the variance associated with the TAQ was not significantly different from zero in any of the estimated models, and thus, the covariance of a and b paths was fixed at zero.
References
Andersson, G. (2009). Using the internet to provide cognitive behaviour therapy. Behaviour Research and Therapy, 47, 175–180. doi:10.1016/j.brat.2009.01.010
Andersson, G., Kaldo-Sandström, V., Ström, L., & Strömgren, T. (2003). Internet administration of the Hospital Anxiety and Depression Scale (HADS) in a sample of tinnitus patients. Journal of Psychosomatic Research, 55, 259–262. doi:10.1016/S0022-3999(02)00575-5
Arch, J. J., & Craske, M. G. (2008). Acceptance and commitment therapy and cognitive behavioral therapy for anxiety disorders: Different treatments, similar mechanisms? Clinical Psychology Science and Practice, 15, 263–279.
Arch, J. J., Wolitzky-Taylor, K. B., Eifert, G. H., & Craske, M. G. (2012). Longitudinal treatment mediation of traditional cognitive behavioral therapy and acceptance and commitment therapy for anxiety disorders. Behaviour Research and Therapy, 50, 463–468. doi:10.1016/j.brat.2012.04.007
Baguley, D. M., Humphriss, R. L., & Hodgson, C. A. (2000). Convergent validity of the tinnitus handicap inventory and the tinnitus questionnaire. Journal of Laryngology and Otology, 114, 840–843.
Bauer, D. J., Preacher, K. J., & Gil, J. M. (2006). Conceptualizing and testing random indirect effects and moderated mediation in multilevel models: New procedures and recommendations. Psychological Methods, 11, 142–163. doi:10.1037/1082-989X.11.2.142
Bond, F. W., & Bunce, D. (2000). Mediators of change in emotion-focused and problem focused worksite stress management interventions. Journal of Occupational Health Psychology, 5, 156–163. doi:10.1037//1076-8998.5.1.156
Davis, A., & El Refaie, A. (2000). Epidemiology of tinnitus. In R. S. Tyler (Ed.), Tinnitus handbook (pp. 1–23). San Diego, CA: Singular.
Davis, C. G., & Morgan, M. S. (2008). Finding meaning, perceiving growth, and acceptance of tinnitus. Rehabilitation Psychology, 53, 128–138. doi:10.1037/0090-5550.53.2.128
Feingold, A. (2009). Effect sizes for growth-modeling analysis for controlled clinical trials in the same metric as for classical analysis. Psychological Methods, 14, 43–53. doi:10.1037/a0014699
Flaxman, P. E., & Bond, F. W. (2010). A randomised worksite comparison of acceptance and commitment therapy and stress inoculation training. Behaviour Research and Therapy, 48, 816–820. doi:10.1016/j.brat.2010.05.004
Forman, E. M., Chapman, J. E., Herbert, J. D., Goetter, E. M., Yuen, E. K., & Moitra, E. (2012). Using session-by-session measurement to compare mechanisms of action for acceptance and commitment therapy and cognitive therapy. Behavior Therapy, 43, 341–354. doi:10.1016/j.beth.2011.07.004
Gregg, J. A., Callaghan, G. M., Hayes, S. C., & Glenn-Lawson, J. L. (2007). Improving diabetes self-management through acceptance, mindfulness, and values: A randomized controlled trial. Journal of Consulting and Clinical Psychology, 75, 336–343. doi:10.1037/0022-006X.75.2.336
Hayes, S. C., Levin, M., Plumb, J., Boulanger, J., & Pistorello, J. (2011). Acceptance and commitment therapy and contextual behavioral science: Examining the progress of a distinctive model of behavioral and cognitive therapy. Behavior Therapy. Advanced online publication. doi:10.1016/j.beth.2009.08.002
Hayes, S. C., Strosahl, K. D., & Wilson, K. G. (1999). Acceptance and commitment therapy. An experiential approach to behavior change. New York: The Guilford Press.
Hayes-Skelton, S. A., Usmani, A., Lee, J. K., Roemer, L, & Orsillo, S. M. (2012). A fresh look at potential mechanisms of change in applied relaxation for generalized anxiety disorder: A case series. Cognitive and Behavioral Practice. Advanced online publication. doi:10.1016/j.cbpra.2011.12.005
Henry, J. A., Dennis, K. C., & Schechter, M. A. (2005). General review of tinnitus: Prevalence, mechanisms, effects, and management. Journal of Speech, Language, and Hearing Research, 48, 1204–1235. doi:10.1044/1092-4388(2005/084
Hesser, H., Gustafsson, T., Lundén, C., Henrikson, O., Fattahi, K., Johnsson, E., et al. (2012). A randomized controlled trial of Internet-delivered cognitive behavior therapy and acceptance and commitment therapy in the treatment of tinnitus. Journal of Consulting and Clinical Psychology, 80, 649–661. doi:10.1037/a0027021
Hesser, H., Molander, P., Jungermann, M., & Andersson, G. (2013). Costs of suppressing emotional sound and countereffects of mindfulness induction: An experimental analog of tinnitus impact. PLoS ONE, 8, e64540. doi:10.1371/journal.pone.0064540
Hesser, H., Pereswetoff-Morath, C. E., & Andersson, G. (2009a). Consequences of controlling background sounds: The effect of experiential avoidance on tinnitus interference. Rehabilitation Psychology, 54, 381–389. doi:10.1037/a0017565
Hesser, H., Weise, C., Zetterqvist Westin, V., & Andersson, G. (2011). A systematic review and meta-analysis of randomized controlled trials of cognitive-behavioral therapy for tinnitus distress. Clinical Psychology Review, 31, 545–553. doi:10.1016/j.cpr.2010.12.006
Hesser, H., Westin, V., Hayes, S. C., & Andersson, G. (2009b). Clients’ in-session acceptance and cognitive defusion behaviors in acceptance-based treatment of tinnitus distress. Behaviour Research and Therapy, 47, 523–528. doi:10.1016/j.brat.2009.02.002
Kaldo, V., Cars, S., Rahnert, M., Larsen, H.-C., & Andersson, G. (2007). Use of a self-help book with weekly therapist contact to reduce tinnitus distress: A randomized controlled trial. Journal of Psychosomatic Research, 63, 195–202. doi:10.1016/j.jpsychores.2007.04.007
Kaldo, V., Levin, S., Widarsson, J., Buhrman, M., Larsen, H.-C., & Andersson, G. (2008). Internet versus group cognitive-behavioral treatment of distress associated with tinnitus: A randomized controlled trial. Behavior Therapy, 39, 348–359.
Kenny, D. A., Korchmaros, J. D., & Bolger, N. (2003). Lower level mediation in multilevel models. Psychological Methods, 8, 115–128.
Kraemer, H. C., Wilson, T., Fairburn, C. G., & Agras, W. S. (2002). Mediators and moderators of treatment effects in randomized clinical trials. Archives of General Psychiatry, 59, 877–883.
Lockwood, A. H., Salvi, R. J., & Burkard, R. F. (2002). Tinnitus. New England Journal of Medicine, 347, 904–910.
MacKinnon, D. P. (2008). Introduction to statistical mediation analysis. New York: Lawrence Erlbaum Associates.
MacKinnon, D. P., Lockwood, C. M., Hoffman, J. M., West, S. G., & Sheets, V. (2002). A comparison of methods to test mediation and other intervening variable effects. Psychological Methods, 7, 83–104. doi:10.1037//1082-989X.7.1.83
MacKinnon, D. P., Lockwood, C. M., & Williams, J. (2004). Confidence limits for the indirect effect: Distribution of the product and resampling methods. Multivariate Behavioral Research, 39, 99–128.
Martinez Devesa, P., Waddell, A., Perera, R., & Theodoulou, M. (2010). Cognitive behavioural therapy for tinnitus. Cochrane Database Systematic Reviews, 9, CD005233. doi:10.1002/14651858.CD005233.pub2
Maxwell, S. E., & Cole, D. A. (2007). Bias in cross-sectional analyses of longitudinal mediation. Psychological Methods, 12, 23–44. doi:10.1037/1082-989X.12.1.23
McCracken, L. M., & Vowles, K. E. (2006). Acceptance of pain. Current Pain and Headache Reports, 10, 90–94.
McCracken, L. M., Vowles, K. E., & Eccleston, C. (2004). Acceptance of chronic pain: Component analysis and a revised assessment method. Pain, 107, 159–166.
McCracken, L. M., Vowles, K. E., & Gauntlett-Gilbert, J. (2007). A prospective investigation of acceptance and control-oriented co** with chronic pain. Journal of Behavioral Medicine, 30, 339–349.
Møller, A. R. (2000). Similarities between severe tinnitus and chronic pain. Journal of the American Academy of Audiology, 11, 115–124.
Morley, S., Eccleston, C., & Williams, A. (1999). Systematic review and meta-analysis of randomized controlled trials of cognitive behaviour therapy and behavior therapy for chronic pain in adults, excluding headache. Pain, 80, 1–13.
Newman, C. W., Jacobson, G. P., & Spitzer, J. B. (1996). Development of the tinnitus handicap inventory. Archives of Otolaryngology Head and Neck Surgery, 122, 143–148.
Newman, C. W., Sandridge, S. A., & Jacobson, G. (1998). Psychometric adequacy of the tinnitus handicap inventory (THI) for evaluating treatment outcome. Journal of the American Academy of Audiology, 9, 153–160.
Preacher, K. J., Zyphur, M. J., & Zhang, Z. (2010). A general multilevel SEM framework for assessing multilevel mediation. Psychological Methods, 15, 209–233. doi:10.1037/a0020141
Raudenbush, S. W., & Bryk, A. S. (2002). Hierarchical linear models: Applications and data analysis methods (2nd ed.). Newbury Park, CA: Sage.
Schafer, J. L., & Graham, J. W. (2002). Missing data: Our view of the state of the art. Psychological Methods, 7, 147–177. doi:10.1037//1082-989X.7.2.147
Scott, B., Lindberg, P., Lyttkens, L., & Melin, L. (1985). Psychological treatment of tinnitus. An experimental group study. Scandinavian Audiology, 14, 223–230. doi:10.3109/01050398509045945
Snijders, T., & Bosker, R. (2012). Multilevel analysis: An introduction to basic and advanced multilevel modeling (2nd ed.). London: Sage.
Sobel, M. E. (1982). Asymptotic confidence intervals for indirect effects in structural equations models. In S. Leinhart (Ed.), Sociological methodology 1982 (pp. 290–312). San Francisco: Jossey-Bass.
Turk, D. C., & Okifuji, A. (2002). Psychological factors in chronic pain: Evolution and revolution. Journal of Consulting and Clinical Psychology, 70, 678–690. doi:10.1037//0022-006X.70.3.678
Veehof, M. M., Oskam, M., Schreurs, K. M. G., & Bohlmeijer, E. T. (2011). Acceptance-based interventions for the treatment of chronic pain: A systematic review and meta-analysis. Pain, 152, 533–542. doi:10.1037//0022-006X.70.3.678
Vowles, K. E., & Thompson, M. (2010). Acceptance and commitment therapy for chronic pain. In L. M. McCracken (Ed.), Mindfulness and acceptance in behavioral medicine: Current theory and practice (pp. 31–60). Oakland, CA: New Harbinger.
Weise, C., Kleinstäuber, M., Hesser, H., Zetterqvist Westin, V., & Andersson, G. (2013). Acceptance of tinnitus: Validation of the tinnitus acceptance questionnaire. Cognitive Behaviour Therapy, 42, 100–115. doi:10.1080/16506073.2013.781670
Westin, V., Hayes, S. C., & Andersson, G. (2008a). Is it the sound or your relationship to it? The role of acceptance in predicting tinnitus impact. Behaviour Research and Therapy, 46, 1259–1265. doi:10.1016/j.brat.2008.08.008
Westin, V., Östergren, R., & Andersson, G. (2008b). The effects of acceptance versus thought suppression for dealing with the intrusiveness of tinnitus. International Journal of Audiology, 47, 184–190.
Zetterqvist Westin, V., Schulin, M., Hesser, H., Karlsson, M., Zare Noe, R., Olofsson, U., et al. (2011). Acceptance and commitment therapy versus tinnitus retraining therapy in the treatment of tinnitus distress: A randomized controlled trial. Behaviour Research and Therapy, 49, 737–747. doi:10.1016/j.brat.2011.08.001
Acknowledgments
This study was funded by a grant from the Swedish Council for Working Life and Social Research to Gerhard Andersson. The preparation of this manuscript was sponsored in part by a grant from the Swedish Research Council (HEAD Linneaus grant). We wish to thank all research collaborates in the original trial: Tore Gustafsson, Charlotte Lundén, Oskar Henrikson, Kidjan Fattahi, Per Carlbring, Elina Mäki-Torkko, and Viktor Kaldo.
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Hesser, H., Westin, V.Z. & Andersson, G. Acceptance as a mediator in internet-delivered acceptance and commitment therapy and cognitive behavior therapy for tinnitus. J Behav Med 37, 756–767 (2014). https://doi.org/10.1007/s10865-013-9525-6
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DOI: https://doi.org/10.1007/s10865-013-9525-6