Abstract
Background
This study aimed to evaluate the use of fat grafting enriched with platelet-rich plasma through a computerized-assisted map** for esthetic restoration in progressive hemifacial atrophy (Parry-Romberg disease).
Methods
This prospective study was conducted on 53 patients presented by Parry-Romberg disease and was corrected by facial fat grafting (FFG) enriched with platelet-rich plasma (PRP). A computerized software program was used to design a detailed map to achieve clinical symmetry with fat grafting application, as the anatomical subunits direct 3-dimensional volumetric symmetric, and compartments direct isolated recipient-specific grafting. Also, volumetric asymmetry was assessed through outlines of facial contour, projection, and proportions for both sides and comparing the mirror image of unaffected side as a template.
Results
Objective ultrasound and photogrammetric measurements showed a significant improvement in facial symmetry postoperatively compared to preoperative (P < 0.05), with no significant differences between 12 and 18 months after surgery. The FACE-Q score regarding comparison before surgery and 18 months after surgery showed a statistically significant improvement in all modules (P < 0.001) with overall satisfaction concerning outcome of 82.7 ± 0.8.
Conclusion
Enriched fat grafting with platelet-rich plasma (PRP) is a good alternative to reconstruct soft tissue defects for patients with progressive hemifacial atrophy (Parry-Romberg disease) with a minimally invasive approach and low complications. It provides volumetric replacement, enhancement of skin texture, and improvement of hyperpigmentation with restoration of facial contour for an esthetic pleasing appearance. Isolated replacement in accordance with the anatomical facial subunits and fat compartments allows three-dimensional reconstruction and maximizes fat retention.
Graphical abstract
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Data availability
The data used and analyzed during the current study are available from the corresponding author on reasonable request.
Change history
01 December 2022
A Correction to this paper has been published: https://doi.org/10.1007/s10006-022-01129-z
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Level of Evidence: Level IV, Therapeutic
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AboShaban, M.S., Ghareeb, F.M. Esthetic restoration of progressive hemifacial atrophy (Parry-Romberg disease) by free fat grafting using computerized-assisted map**. Oral Maxillofac Surg 28, 195–203 (2024). https://doi.org/10.1007/s10006-022-01115-5
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DOI: https://doi.org/10.1007/s10006-022-01115-5