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Light orthodontic force with high-frequency vibration accelerates tooth movement with minimal root resorption in rats

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Abstract

Objectives

To determine and compare the effects of high-frequency mechanical vibration (HFV) with light force and optimal force on the tooth movement and root resorption in rat model.

Materials and methods

Seventy-two sites in 36 male Wistar rats were randomly assigned using a split-mouth design to control (no force/no vibration) or experimental groups: HFV (125 Hz), light force (5 g), optimal force (10 g), light force with HFV, and optimal force with HFV for 14 and 21 days. The amount of tooth movement, 3D root volume, and root resorption area were assessed by micro-computed tomography and histomorphometric analysis.

Results

Adjunction of HFV with light force significantly increased the amount of tooth movement by 1.8-fold (p = 0.01) and 2.0-fold (p = 0.01) at days 14 and 21 respectively. The HFV combined with optimal force significantly increased the amount of tooth movement by 2.1-fold (p = 0.01) and 2.2-fold (p = 0.01) at days 14 and 21 respectively. The root volume in control (distobuccal root (DB): 0.60 ± 0.19 mm3, distopalatal root (DPa): 0.60 ± 0.07 mm3) and HFV (DB: 0.60 ± 0.08 mm3, DPa: 0.59 ± 0.11 mm3) were not different from the other experimental group (range from 0.44 ± 0.05 to 0.60 ± 0.1 mm3) with the lowest volume in optimal force group.

Conclusions

Adjunction of HFV with orthodontic force significantly increased tooth movement without causing root resorption.

Clinical relevance

Using light force with HFV could help to identify alternative treatment option to reduce the risk of root resorption.

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Acknowledgements

We thank the Research Center, Faculty of Dentistry, Prince of Songkla University, for their kind assistance.

Funding

This research was supported by a grant from the Graduate School and Faculty of Dentistry, Prince of Songkla University (PSU).

Author information

Authors and Affiliations

  1. Orthodontic Resident, Department of Preventive Dentistry, Faculty of Dentistry, Prince of Songkla University, Hat Yai, Songkhla, 90112, Thailand

    Porntip Tangtanawat & Chidchanok Leethanakul

  2. Institute of Dentistry, Suranaree University of Technology, Mueang Nakhon Ratchasima, Nakhon Ratchasima, 90112, Thailand

    Peungchaleoy Thammanichanon

  3. Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Prince of Songkla University, Hat Yai, Songkhla, 90112, Thailand

    Srisurang Suttapreyasri

  4. Oral Neuroscience and Molecular Biology of Dental Pulp and Bone Cells Research Unit, Prince of Songkla University, Songkhla, 90112, Thailand

    Chidchanok Leethanakul

Authors
  1. Porntip Tangtanawat
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Contributions

Porntip Tangtanawat: conceptualization, methodology, investigation, data curation, formal analysis, writing—original draft, visualization.

Peungchaleoy Thammanichanon: methodology, investigation, data curation.

Srisurang Suttapreyasri: validation, writing—review and editing, supervision, project administration.

Chidchanok Leethanakul: validation, writing—review and editing, supervision, project administration.

Corresponding author

Correspondence to Chidchanok Leethanakul.

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Ethical approval

All experiments were reviewed and approved by the Animal Ethics Committee of Prince of Songkla University (2562-05-061). All applicable international and national institutional guidelines for the care and use of animals were followed.

Competing interests

The authors declare no competing interests.

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Tangtanawat, P., Thammanichanon, P., Suttapreyasri, S. et al. Light orthodontic force with high-frequency vibration accelerates tooth movement with minimal root resorption in rats. Clin Oral Invest 27, 1757–1766 (2023). https://doi.org/10.1007/s00784-022-04804-3

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