Dear Editor:

I would like to thank Yuce İslamoglu for the pertinent reference to the COVID-19 variant in our recent study testing the use of intra-nasal nitrilotriacetic acid trisodium salt to improve olfactory dysfunction in COVD-19 patients [1].

I carefully read the article by Yuce İslamoglu et al. which investigated the difference in nasal mucosal secretion between anosmic COVID-19 patients, dominant Wuhan COVID-19 variant and healthy subjects. The results showed that there was no difference between the groups [2].

As shown by different studies, different variants have different effects on nasal mucosa [3,4,5]. In our study, the Wuhan variant was the dominant COVID-19 variant.