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Eminently sensitive mono-rectangular photonic crystal fiber-based sensor for cancer cell detection in THz regime

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Abstract

The present study reports a design procedure and numerical investigation of a photonic crystal fiber biosensor. The proposed sensor is consisting of irregular arranged rectangular holes. The core area has been arranged of a single rectangle for sensing the cancer cells and normal cells in the frequency range 1.0–2.5 THz. Zeonex has been utilized as a fiber material. The model has been organized and computationally investigated employing software based on the finite element method. The modeling of the designed sensor authenticates its capability in identifying cancer cells. An absorbing layer: perfectly matched layer has been used for calculating optical characteristics. It has been observed that the designed PCF sensor gives a high relative sensitivity of 81.38% for cancer cells and 65.83% for normal cells, respectively. Reduced confinement loss as 5.828 × 10−25 cm−1 has been achieved. Also, the effective area 2.549 × 10−8 µm2, birefringence 4.709 × 10−4, propagation constant  1.01961 × 10−24 and effective refractive index as 1.475 × 10−18 have been investigated. The present manufacturing technique is appropriate for the designing of proposed PCF sensor.

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Acknowledgements

The author is very grateful to Dr. Vijay Shanker Choudhary, Galgotias University and Dr. Sachin Singh, IAAM Sweden for their valuable support.

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Authors and Affiliations

  1. Photonics and Photovoltaic Research Lab, Department of Physics and Material Science, Madan Mohan Malaviya University of Technology, Gorakhpur, 273010, India

    Sapana Yadav & D. K. Dwivedi

  2. Department of Electronics and Communication Engineering, Madan Mohan Malaviya University of Technology, Gorakhpur, 273010, India

    Pooja Lohia

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SY: original manuscript writing, methodology, software analysis, conceptualization while DKD and PL: reviewing, editing and supervision.

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Yadav, S., Lohia, P. & Dwivedi, D.K. Eminently sensitive mono-rectangular photonic crystal fiber-based sensor for cancer cell detection in THz regime. J Opt 53, 528–537 (2024). https://doi.org/10.1007/s12596-023-01191-0

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