Photonic Crystal Fiber-Based Biosensor for Sensitive Detection of Breast Cancer Cells in THz Regime

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Recent Advances in Nanotechnology (ICNOC 2022)

Part of the book series: Springer Proceedings in Materials ((SPM,volume 28))

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Abstract

A hollow-core photonic crystal fiber-based THz sensor that enables to detect analytes at terahertz frequencies is presented in this study, which is characterized by its robustness. An analyte gets inserted in an asymmetrical rectangular hollow core with perfectly matched layer absorbent boundary condition. The efficiency of proposed sensor is evaluated utilizing COMSOL multiphysics (v5.5a) simulation technology based on the finite element technique. The proposed sensor's design simplicity makes things a lot easier. Fabrication, on the other side, makes it appropriate for a broad range of biological and industrial applications. A photonic crystal fiber biosensor has been studied for detecting cancerous cells. The proposed model's efficiency has been evaluated using MATLAB (v.2018a) software. The proposed sensor may work in the frequency range of 1.0–2.0 THz. Simulation results have been found to be good enough, with highly birefringence (0.0020) and lower confinement loss (17.33 × 10–9 cm−1). The proposed sensor's fabrication capabilities are further secured by its simplicity of implementation and can be utilized in bio-sensing application.

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References

  1. Ademgil H, Haxha S (2016) Highly birefringent nonlinear PCF for optical sensing of analytes in aqueous solutions. Optik 127(16):6653–6660

    Article  CAS  Google Scholar 

  2. Ahmed K, Ahmed F, Roy S, Paul BK, Aktar MN, Vigneswaran D, Islam MS (2019) Refractive index-based blood components sensing in Terahertz spectrum. IEEE Sens J 19(9):3368–3375

    Article  CAS  Google Scholar 

  3. Asaduzzaman S, Ahmed K, Bhuiyan T, Farah T (2016) Hybrid photonic crystal fiber in chemical sensing. SpringerPlus 5(1)

    Google Scholar 

  4. Bise RT, Trevor DJ (2005) Sol–gel derived microstructured fiber: Fabrication and characterization. Conf Opt Fiber Commun Tech Dig Ser 3:269–271

    Google Scholar 

  5. Bulbul AAM, Kouzani AZ, Mahmud MAP, Nahid AA (2021) Design and numerical analysis of a novel rectangular PCF (R-PCF)-based biochemical sensor (BCS) in the THz regime. Int J Opt

    Google Scholar 

  6. Hasan MM, Sen S, Rana MJ, Paul BK, Habib MA, Daiyan GM, Ahmed K (2019) Heptagonal photonic crystal fiber based chemical sensor in THz regime. In: 2019 joint 8th international conference on informatics, electronics and vision, ICIEV 2019 and 3rd international conference on imaging, vision and pattern recognition, IcIVPR 2019 with international conference on activity and behavior computing. ABC 2019, pp 40–44

    Google Scholar 

  7. Islam MS, Sultana J, Ahmed K, Islam MR, Dinovitser A, Ng BWH, Abbott D (2018) A novel approach for spectroscopic chemical identification using photonic crystal fiber in the terahertz regime. IEEE Sens J 18(2):575–582

    Article  CAS  Google Scholar 

  8. Paul BK, Ahmed K, Asaduzzaman S, Islam MS (2017) Folded cladding porous shaped photonic crystal fiber with high sensitivity in optical sensing applications: design and analysis. Sens Bio-Sens Res 12:36–42

    Article  Google Scholar 

  9. Sen S, Abdullah-Al-Shafi M, Sikder AS, Hossain MS, Azad MM (2021) Zeonex based decagonal photonic crystal fiber (D-PCF) in the terahertz (THz) band for chemical sensing applications. Sens Bio-Sens Res 31:100393

    Google Scholar 

  10. Shephard JD, MacPherson WN, Maier RRJ, Jones JDC, Hand DP, Mohebbi M, George AK, Roberts PJ, Knight JC (2005) Single-mode mid-IR guidance in a hollow-core photonic crystal fiber. Opt Express 13(18):7139

    Article  CAS  Google Scholar 

  11. Wang XD, Wolfbeis OS (2016) Fiber-optic chemical sensors and biosensors (2013–2015). Anal Chem 88(1):203–227

    Article  CAS  Google Scholar 

  12. Yadav S, Singh S, Lohia P, Umar A, Dwivedi DK (2022) Delineation of profoundly birefringent nonlinear photonic crystal fiber in terahertz frequency regime. J Opt Commun

    Google Scholar 

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Acknowledgements

The author expresses gratitude to MMMUT, Gorakhpur, for awarding research cum teaching fellowship that has enabled the continuation of my research work. I also acknowledge the valuable suggestions provided by Prof. D. K. Dwivedi.

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Correspondence to D. K. Dwivedi .

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Yadav, S., Lohia, P., Dwivedi, D.K. (2023). Photonic Crystal Fiber-Based Biosensor for Sensitive Detection of Breast Cancer Cells in THz Regime. In: Khan, Z.H., Jackson, M., Salah, N.A. (eds) Recent Advances in Nanotechnology. ICNOC 2022. Springer Proceedings in Materials, vol 28. Springer, Singapore. https://doi.org/10.1007/978-981-99-4685-3_41

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