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Dietary supplementation with curcumin nanomicelles, curcumin, and turmeric affects growth performance and silver nanoparticle toxicity in Cyprinus carpio

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Abstract

An 8-week feeding experiment was conducted to investigate the effects of curcumin nanomicelle, curcumin, and turmeric (Curcuma longa) on growth performances, body composition, fatty acid profile, and biochemical parameters of common carp (Cyprinus carpio), and their ameliorative effects against toxicity of silver nanoparticles (AgNPs). A total of 120 healthy carps were randomly distributed into four equal treatments. Curcumin nanomicelle, curcumin, and turmeric were each added separately to the basal diet. After the feeding trials, all treatments were exposed to a non-lethal concentration of AgNPs (0.5 mg L−1) for 96 h. Fish fed dietary turmeric showed a significantly higher weight gain. The body protein content was significantly increased in all feeding groups, while the lipid content showed a significant decrease in the turmeric-treated group. Dietary turmeric improved the concentration of saturated fatty acids (SFA) and monounsaturated fatty acid (MUFA). AgNP exposure led to increases in liver catalase (CAT) activity of carps fed with turmeric and curcumin. The lowest amount of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) was obtained in fish fed with nanomicelle curcumin and curcumin diets. The lowest amount of silver accumulation in the liver of carps was found in fish fed with dietary curcumin nanomicelle. This experiment suggests that supplementation of turmeric (50 g kg−1) or curcumin (1000 mg kg−1) may play an important role in enhancing growth performances and fatty acid composition of the common carp. Moreover, administration of curcumin nanomicelle in the diet may have a potential ameliorative effect against toxicity of AgNPs.

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Acknowledgements

The authors are grateful to Exir Nano Sina Co. (Iran) for donating nanomicelles encapsulated curcumin (SinaCurcumin®).

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All data and materials are included in this published article.

Funding

This work was supported by the University of Kurdistan (Grant number: GRC97-06503-1).

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Authors and Affiliations

  1. Department of Fisheries, Faculty of Natural Resources, University of Kurdistan, P.O. Box 416, Sanandaj, 66177-15175, Iran

    Fereshteh Pirani, Shadieh Moradi, Seyed Ali Johari & Edris Ghaderi

  2. Centre of Marine Sciences (CCMAR), Universidade do Algarve, Campus de Gambelas, 8005-139, Faro, Portugal

    Samyar Ashouri

  3. Department of Zrebar Lake Environmental Research, Kurdistan Studies Institute, University of Kurdistan, Sanandaj, Iran

    Seyed Ali Johari

  4. Institute of Nanoproduct Safety Research, Hoseo University, Asan, Korea

    Hoi Pin Kim

  5. T CO., LTD., Icheon, Republic of Korea

    Il Je Yu

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  1. Fereshteh Pirani
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FP: investigation, data curation; SM: investigation; SA: investigation, data curation, writing—original draft preparation; SAJ: supervision, conceptualization, methodology, funding acquisition, project administration, writing—review and editing; EG: investigation; HPK: investigation; IJY: conceptualization, methodology

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Correspondence to Seyed Ali Johari.

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Pirani, F., Moradi, S., Ashouri, S. et al. Dietary supplementation with curcumin nanomicelles, curcumin, and turmeric affects growth performance and silver nanoparticle toxicity in Cyprinus carpio. Environ Sci Pollut Res 28, 64706–64718 (2021). https://doi.org/10.1007/s11356-021-15538-2

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