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Hemodynamics During Development and Postnatal Life

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Congenital Heart Diseases: The Broken Heart

Abstract

Unlike other embryonic organs, the develo** heart must support, through its proper function, the develo** embryo from the time diffusion becomes limiting. Hemodynamics is thus not only a key to remodeling of the develo** vasculature but also a powerful stimulus for cardiac growth and differentiation. In this chapter are discussed prenatal models of hemodynamic perturbation that help clarifying the role of blood flow in embryogenesis.

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Acknowledgments

This is supported by the Ministry of Education PRVOUK-P35/LF1/5 and institutional funding from the Academy of Sciences of the Czech Republic RVO: 67985823. Further support comes from Grant Agency of the Czech Republic 13-12412S and P302/11/1308.

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Authors and Affiliations

  1. Department of Cardiovascular Morphogenesis, Institute of Physiology, The Czech Academy of Sciences, Prague, Czech Republic

    David Sedmera

  2. Institute of Anatomy, First Faculty of Medicine Charles University in Prague, Prague, Czech Republic

    David Sedmera

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  1. David Sedmera
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Correspondence to David Sedmera .

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Editors and Affiliations

  1. Cardiovascular Genetics, Charité - Universitätsmedizin Berlin , Berlin, Germany

    Silke Rickert-Sperling

  2. Developmental Biology, Inst. of Marseilles, Aix-Marseille Univ. , Marseille, France

    Robert G. Kelly

  3. Dpt. of Pediatrics Div.of Pediatric Card, Mayo Clinic College of Medicine, Rochester, Minnesota, USA

    David J. Driscoll

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Sedmera, D. (2016). Hemodynamics During Development and Postnatal Life. In: Rickert-Sperling, S., Kelly, R., Driscoll, D. (eds) Congenital Heart Diseases: The Broken Heart. Springer, Vienna. https://doi.org/10.1007/978-3-7091-1883-2_9

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