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Clinical and Surgical Management of Pediatric Diseases of the Salivary Glands

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Abstract

This chapter outlines the management of the most frequently occurring diseases of the salivary glands in children including ranula, simple cysts, sialolithiasis, recurrent parotitis, hemangioma, pleomorphic adenoma, and malignant tumors. Clues are provided to assist in diagnosis; radiological investigations, including ultrasound, cross sectional imaging, and sialoendoscopy, are discussed. Trends toward interventional approaches rather than open surgeries are discussed. It is acknowledged that evidence for treatment is mostly based on single-center studies. The natural history of salivary gland tumors mandates lifelong surveillance in some cases.

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References

  1. Wong MP, Yuen ST, Collins RJ. Fine-needle aspiration biopsy of pilomatrixoma: still a diagnostic trap for the unwary. 1994;10(4):365–369; discussion 369–70.

    Google Scholar 

  2. Simon Cypel TK, Vijayasekaran V, Somers GR, Zuker RM. Pilomatricoma: experience of the hospital for sick children. Can J Plast Surg. 2007;15(3):159–61.

    Article  Google Scholar 

  3. Stevens E, Andreasen S, Bjorndal K, Homoe P. Tumors in the parotid are not relatively more often malignant in children than in adults. Int J Pediatr Otorhinolaryngol. 2015;79(8):1192–5.

    Article  CAS  Google Scholar 

  4. Kessler A, Handler SD. Salivary gland neoplasms in children: a 10-year survey at the Children’s Hospital of Philadelphia. Int J Pediatr Otorhinolaryngol. 1994;29(3):195–202.

    Article  CAS  Google Scholar 

  5. Bradley PJ, McGurk M. Incidence of salivary gland neoplasms in a defined UK population. Br J Oral Maxillofac Surg. 51(5):399–403.

    Google Scholar 

  6. Etit D, Ekinci N, Tan A, Altinel D, Dag F. An analysis of salivary gland neoplasms: a 12-year, single-institution experience in Turkey. Ear Nose Throat J. 2012;91(3):125–9.

    Article  Google Scholar 

  7. Lee YM, Choi HJ, Kim JW, Kim JH. Parotid gland tumors in a Korean population. J Craniofac Surg. 2012;23(3):e205–9.

    Article  Google Scholar 

  8. Ellies M, Schaffranietz F, Arglebe C, Laskawi R. Tumors of the salivary glands in childhood and adolescence. J Oral Maxillofac Surg. 64(7):1049–58.

    Google Scholar 

  9. Fang Q-G, Shi S, Li Z-N, Zhang X, Liu F-Y, Sun C-F. Epithelial salivary gland tumors in children: a twenty-five-year experience of 122 patients. Int J Pediatr Otorhinolaryngol. 77(8):1252–4.

    Google Scholar 

  10. Martins-Carvalho C, Plouin-Gaudon I, Quenin S, Lesniak J, Froehlich P, Marchal F, et al. Pediatric sialendoscopy: a 5-year experience at a single institution. Arch Otolaryngol Head Neck Surg. 2010;136(1):33–6.

    Article  Google Scholar 

  11. ST O, SR P. Pediatric skull base plunging ranula: case report and review of the literature. International Journal of Pediatric Otorhinolaryngology Extra. 2007;2(1):54–7.

    Article  Google Scholar 

  12. Crysdale WS, Raveh E, McCann C, Roske L, Kotler A. Management of drooling in individuals with neurodisability: a surgical experience. Dev Med Child Neurol. 2001;43(6):379–83.

    Article  CAS  Google Scholar 

  13. Pownell PH, Brown OE, Pransky SM, Manning SC. Congenital abnormalities of the submandibular duct. Int J Pediatr Otorhinolaryngol. 1992;24(2):161–9.

    Article  CAS  Google Scholar 

  14. Zhao YF, Jia J, Jia Y. Complications associated with surgical management of ranulas. J Oral Maxillofac Surg. 2005;63(1):51–4.

    Article  Google Scholar 

  15. Patel MR, Deal AM, Shockley WW. Oral and plunging ranulas: what is the most effective treatment? Laryngoscope. 2009;119(8):1501–9.

    Article  Google Scholar 

  16. Rho MH, Kim DW, Kwon JS, Lee SW, Sung YS, Song YK, et al. OK-432 sclerotherapy of plunging ranula in 21 patients: it can be a substitute for surgery. AJNR Am J Neuroradiol. 2006;27(5):1090–5.

    CAS  PubMed  PubMed Central  Google Scholar 

  17. Seifert G. Mucoepidermoid carcinoma in a salivary duct cyst of the parotid gland. Contribution to the development of tumors in salivary gland cysts Pathol Res Pract. 1996;192(12):1211–7.

    CAS  PubMed  Google Scholar 

  18. Venkateswaran L, Gan YJ, Sixbey JW, Santana VM. Epstein-Barr virus infection in salivary gland tumors in children and young adults. Cancer. 2000;89(2):463–6.

    Article  CAS  Google Scholar 

  19. Steiner M, Gould AR, Kushner GM, Weber R, Pesto A. Sialolithiasis of the submandibular gland in an 8-year-old child. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1997;83(2):188.

    Article  CAS  Google Scholar 

  20. Schafer W. Physical and chemical injuries of the oral cavity. 4th ed. Philadelphia: WB Saunders Co; 1983. p. 561.

    Google Scholar 

  21. Brown JE, Escudier MP, Whaites EJ, Drage NA, Ng SY. Intra-oral ultrasound imaging of a submandibular duct calculus. Dentomaxillofac Radiol. 1997;26(4):252–5.

    Article  CAS  Google Scholar 

  22. Ogden MA, Rosbe KW, Chang JL. Pediatric sialendoscopy indications and outcomes. Curr Opin Otolaryngol Head Neck Surg. 2016;24(6):529–35.

    Article  Google Scholar 

  23. Munden A, Butschek R, Tom WL, Marshall JS, Poeltler DM, Krohne SE, et al. Prospective study of infantile haemangiomas: incidence, clinical characteristics and association with placental anomalies. Br J Dermatol. 2014;170(4):907–13.

    Article  CAS  Google Scholar 

  24. Kwon EK, Seefeldt M, Drolet BA. Infantile hemangiomas: an update. Am J Clin Dermatol. 2013;14(2):111–23.

    Article  Google Scholar 

  25. Bentz BG, Hughes CA, Lüdemann JP, Maddalozzo J. Masses of the salivary gland region in children. Arch Otolaryngol Head Neck Surg. 2000;126(12):1435–9.

    Article  CAS  Google Scholar 

  26. Fu H, Wang J, Wang L, Zhang Z, He Y. Pleomorphic adenoma of the salivary glands in children and adolescents. J Pediatr Surg. 2012;47(4):715–9.

    Article  Google Scholar 

  27. Koral K, Sayre J, Bhuta S, Abemayor E, Lufkin R. Recurrent pleomorphic adenoma of the parotid gland in pediatric and adult patients: value of multiple lesions as a diagnostic indicator. AJR Am J Roentgenol. 2003;180(4):1171–4.

    Article  Google Scholar 

  28. Hughes CA, Brown J. Pediatric trans-oral submandibular gland excision: a safe and effective technique. Int J Pediatr Otorhinolaryngol. 2017;93:13–6.

    Article  CAS  Google Scholar 

  29. Bradley PJ, McGurk M. Incidence of salivary gland neoplasms in a defined UK population. Br J Oral Maxillofac Surg. 2013;51(5):399–403.

    Article  Google Scholar 

  30. Lack EE, Upton MP. Histopathologic review of salivary gland tumors in childhood. Arch Otolaryngol Head Neck Surg. 1988;114(8):898–906.

    Article  CAS  Google Scholar 

  31. Thompson L. World Health Organization classification of tumors: pathology and genetics of head and neck tumors. Ear Nose Throat J. 2006;85(2):74.

    Article  Google Scholar 

  32. Spiro RH. Salivary neoplasms: overview of a 35-year experience with 2,807 patients. Head Neck Surg. 1986;8(3):177–84.

    Article  CAS  Google Scholar 

  33. TNM Classification of Malignant Tumors. 8th Edition: Wiley; 2016.

    Google Scholar 

  34. Sood S, McGurk M, Vaz F. Management of Salivary Gland Tumors: United Kingdom National Multidisciplinary Guidelines. J Laryngol Otol. 2016;130(S2):S142–S9.

    Article  CAS  Google Scholar 

  35. Baker SR, Malone B. Salivary gland malignancies in children. Cancer. 1985;55(8):1730–6.

    Article  CAS  Google Scholar 

  36. PJ B. BE H. salivary gland disorders and diseases: diagnosis and management: Thieme; 2011.

    Google Scholar 

  37. Orvidas LJ, Kasperbauer JL, Lewis JE, Olsen KD, Lesnick TG. Pediatric parotid masses. Arch Otolaryngol Head Neck Surg. 2000;126(2):177–84.

    Article  CAS  Google Scholar 

  38. Cockerill CC, Gross BC, Contag S, Rein S, Moore EJ, Olsen KD, et al. Pediatric malignant salivary gland tumors: 60 year follow up. Int J Pediatr Otorhinolaryngol. 2016;88:1–6.

    Article  Google Scholar 

  39. Castro EB, Huvos AG, Strong EW, Foote FW. Tumors of the major salivary glands in children. Cancer. 1972;29(2):312–7.

    Article  CAS  Google Scholar 

  40. KAUFFMAN SL, STOUT AP. Tumors of the major salivary glands in children. Cancer. 1963;16:1317–31.

    Article  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Royal Belfast Hospital for Sick Children, Queen’s University Belfast, Belfast, UK

    Keith Trimble

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  1. Keith Trimble
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Correspondence to Keith Trimble .

Editor information

Editors and Affiliations

  1. Department of Otolaryngology – Head & Neck Surgery, University of Toronto, Toronto, ON, Canada

    Paolo Campisi

  2. Department of Otolaryngology – Head & Neck Surgery, University of Toronto, Toronto, ON, Canada

    Vito Forte

  3. Division of Pathology, Paediatric Laboratory, Hospital for Sick Children Division of Pathology, Toronto, ON, Canada

    Bo-Yee Ngan

  4. Division of Pathology, Department of Laboratory Medicine (retired), Hospital for Sick Children, Toronto, ON, Canada

    Glenn Taylor

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Trimble, K. (2021). Clinical and Surgical Management of Pediatric Diseases of the Salivary Glands. In: Campisi, P., Forte, V., Ngan, BY., Taylor, G. (eds) Pediatric Head and Neck Textbook. Springer, Cham. https://doi.org/10.1007/978-3-030-59265-3_16

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  • DOI: https://doi.org/10.1007/978-3-030-59265-3_16

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-59263-9

  • Online ISBN: 978-3-030-59265-3

  • eBook Packages: MedicineMedicine (R0)

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