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  1. Monoclonal Gammopathies with Miscellaneous Associations

    The list of diseases and syndromes eventually proving to be associated with monoclonal gammopathies, or paraproteinemias is progressively expanding....
    Pietro Enrico Pioltelli, T. Prescott Atkinson, ... Gaafar Ragab in Paraproteinemia and Related Disorders
    Chapter 2022
  2. Clinical characteristics and outcomes in risk-stratified patients with smoldering multiple myeloma: data from the Czech Republic Registry of Monoclonal Gammopathies

    Smoldering multiple myeloma (SMM) is an asymptomatic precursor to active multiple myeloma (MM). The aim of this study was to report clinical...

    Viera Sandecka, Tereza Popkova, ... Ivan Spicka in Blood Cancer Journal
    Article Open access 27 September 2023
  3. Gammopathies

    Hypergammaglobulinemia results from a pathologically increased production of γ globulins, that can be either mono- or polyclonal. Monoclonal...
    Dan Lipsker, Peter Thomas in Braun-Falco´s Dermatology
    Reference work entry 2022
  4. Association of routine hematological parameters with the development of monoclonal gammopathies: a case-control study of 134,740 patients

    The diagnosis of multiple myeloma requires detection of paraproteinemia and confirmation of monoclonal bone marrow infiltration, along with signs of...

    Jakob Røllum-Larsen, Anna Elise Engell, ... Henrik Løvendahl Jørgensen in Annals of Hematology
    Article Open access 06 June 2024
  5. Gammopathies—Jewel in the Crown

    In 1955 JW divorced Elisabet and in 1957 he remarried a research nurse from Uppsala. He moved into a nice house and would within 4 years be the...
    Chapter 2023
  6. Elevated polyclonal IgG4 mimicking a monoclonal gammopathy in IgG4-related disease—a case-based review

    IgG4-related diseases (IgG-RDs) are a group of fibroinflammatory diseases that affect a variety of tissues, resulting in tumour-like effects and/or...

    Chunlei Lu, Dafeng He, ... ** Bao in Clinical Rheumatology
    Article 11 July 2024
  7. Immunophenotypic assessment of clonal plasma cells and B-cells in bone marrow and blood in the diagnostic classification of early stage monoclonal gammopathies: an iSTOPMM study

    Monoclonal gammopathy of undetermined significance (MGUS) is the earliest discernible stage of multiple myeloma (MM) and Waldenström’s...

    Oihane Pérez-Escurza, Juan Flores-Montero, ... Alberto Orfao in Blood Cancer Journal
    Article Open access 11 December 2023
  8. New or Unusual Skin Manifestations in Monoclonal Gammopathies

    Skin manifestations associated with monoclonal gammopathy (MG) are common and can present with various clinical and pathological aspects. They can be...
    Nicolas Ortonne, Saskia Ingen-Housz-Oro in New and Emerging Entities in Dermatology and Dermatopathology
    Chapter 2021
  9. Monoclonal gammopathy in the setting of Pyoderma gangrenosum

    Pyoderma gangrenosum (PG) is a neutrophilic dermatosis characterized by ulcerative painful lesions with violaceous undermined borders. Up to 75% of...

    Vahide Saeidi, Vishal Garimella, ... Afsaneh Alavi in Archives of Dermatological Research
    Article 25 May 2024
  10. Serum monoclonal immunoglobulin light-chain detection differs between immunofixation electrophoresis methods in patients with AL amyloidosis

    Serum immunofixation electrophoresis (IFE) is often performed for screening monoclonal proteins (M proteins) in immunoglobulin light-chain...

    Yawara Kawano, Nao Nishimura, Jun-Ichirou Yasunaga in International Journal of Hematology
    Article 13 May 2024
  11. Polymyositis and Polyneuropathy Associated with IgGk Monoclonal Gammopathy in Long COVID

    The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to an increased recognition of its potential to induce...

    Daniil Degterev, Valentina Mikhailova, ... Elizaveta Makashova in BioNanoScience
    Article 25 April 2024
  12. Paraproteinemia Associated Myopathy

    Monoclonal gammopathy refers to an increase in a single immunoglobulin class that may occur in association with normal or reduced levels of the other...
    Chapter 2023
  13. Cutaneous manifestations of monoclonal gammopathy

    Monoclonal gammopathy associated with dermatological manifestations are a well-recognized complication. These skin disorders can be associated with...

    Jean-Sebastien Claveau, David A. Wetter, Shaji Kumar in Blood Cancer Journal
    Article Open access 11 April 2022
  14. Proliferative glomerulonephritis with monoclonal IgG Lambda deposits caused by plasmablastic lymphoma: a case report

    Introduction

    As a very rare form of B-cell lymphoma, plasmablastic lymphoma (PBL) typically occurs in patients with underlying immunosuppression,...

    Ling-Yan Ren, Qi Chen, ... Zhan-Qin Shi in BMC Nephrology
    Article Open access 06 October 2023
  15. Successful use of lenalidomide to treat refractory acquired von Willebrand disease associated with monoclonal gammopathy

    Acquired von Willebrand syndrome (AVWS) is a rare hematologic disorder characterized by quantitative or qualitative defects of von Willebrand factor...

    Allen Green, Yu-Min P. Shen, ... Sean G. Yates in Annals of Hematology
    Article 04 October 2022
  16. A case of proliferative glomerulonephritis with monoclonal IgG deposits (PGNMID) that responded favorably to steroid therapy

    Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID) generally has a poor prognosis and the consensus is that it needs...

    Yoshiyasu Ogura, Sayaka Yabushita, ... Naobumi Mise in CEN Case Reports
    Article 10 October 2021
  17. Gammopathies

    Hypergammaglobulinemia results from a pathologically increased production of γ globulins, that can be either mono- or polyclonal. Monoclonal...
    Dan Lipsker, Peter Thomas in Braun-Falco´s Dermatology
    Living reference work entry 2020
  18. Triclonal Gammopathy in Multiple Myeloma with Bleeding Diathesis: A Case Report

    Introduction

    Gammopathies have clinical and diagnostic significance for lymphoproliferative disorders and plasma cell dyscrasias such as multiple...

    H. R. Samruddhi, Srikantiah Rukmini Mysore, ... Sharada Rai in Indian Journal of Clinical Biochemistry
    Article 22 April 2024
  19. Protein Diagnostics

    Protein diagnostics mainly deals with monoclonal gammopathies, conditions characterized by the presence of a monoclonal immunoglobulin (or part of...
    Maria Stella Graziani, Anna Caldini in Clinical and Laboratory Medicine Textbook
    Chapter 2023
  20. Long Term Remission of Capillary Leak Syndrome Associated with Monoclonal Gammopathy with Progression to Multiple Myeloma After Autologous Stem Cell Transplantation: a Case Report and Review of the Literature

    Background

    Clarkson’s disease is a very rare entity characterised by acute episodes of systemic oedema and severe hypotension associated with...

    Gerardo Hermida, Rodolfo Alvarez-Nuño, ... Tomás José González-López in Oncology and Therapy
    Article Open access 02 February 2024
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