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Almond miRNA Expression and Horticultural Implications
From the past, till now various improved almond cultivars with desired traits have been introduced through breeding programs based on classical and... -
Determining miRNA Expression Patterns in Xenopus
Whole-mount in situ hybridization (WISH) is a technique that enables temporal and spatial visualization of RNA molecules in an embryo or whole tissue... -
miRNA Dysregulation in Schizophrenia
Schizophrenia is a complex neuropsychiatric disorder that alters synapse activity as well as neural circuits. An intricate intracellular network of... -
Altered expression of serum lncRNA CASC2 and miRNA-21-5p in COVID-19 patients
Infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19) has a high incidence of...
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Identification of miRNA expression profile in middle ear cholesteatoma using small RNA-sequencing
BackgroundThe present study aims to identify the differential miRNA expression profile in middle ear cholesteatoma and explore their potential roles...
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Evaluation of miRNA Expression in 3D In Vitro Scaffold-Based Cancer Models
Accumulating experimental evidence suggests that 3D in vitro cancer models strengthen our understanding of vital processes in the tumor... -
Trimethylamine-N-oxide, a New Risk Factor for Non-alcoholic Fatty Liver Disease Changes the Expression of miRNA-34a, and miRNA-122 in the Fatty Liver Cell Model
Non-alcoholic fatty liver disease is a multifactorial disorder with complicated pathophysiology ranging from simple steatosis to steatohepatitis and...
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Oxford miRNA Gardener
Genetic traits are a curious question for biological research to elucidate the etiology of pathogenesis and are transmitted from cell to cell,... -
Association between miRNA-145 and miRNA-155 expression in peripheral blood mononuclear cells of patients with multiple sclerosis: a case-control study
IntroductionMicroRNAs (miR or miRNA) are short regulatory RNAs, which modulate post-transcriptional gene expression. Dysregulation of these molecules...
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miRNA-200c-3p deficiency promotes epithelial-mesenchymal transition in triple-negative breast cancer by activating CRKL expression
Epithelial-mesenchymal transition (EMT) plays an important role in malignant progression of Triple-negative breast cancer (TNBC). Many studies have...
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An Efficient CRISPR-Cas9 Method to Knock Out MiRNA Expression in Xenopus Tropicalis
In recent years CRISPR-Cas9 knockouts (KO) have become increasingly utilized to study gene function. MicroRNAs (miRNAs) are short noncoding RNAs,... -
Profiling salivary miRNA expression levels in Fanconi anemia patients – a pilot study
The overarching goal of this study is to predict the risk of develo** oral squamous cell carcinoma (OSCC) in Fanconi anemia (FA) patients. We have...
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Programmed Evolution by miRNA Memory
Diseases are deeply implicated in the aberrant expression of microRNA (miRNA) genes. The RNA Wave 2000 dogma consists of four criteria, as first... -
MiRNA Immunity Against Virus and MiRNA Surveillance Against Tumor
Through the microRNA (miRNA) entangling target sorting/quantum miRNA language plus artificial intelligence (METS/MIRAI) analysis so far, it seems... -
Integrative network analysis of miRNA-mRNA expression profiles during epileptogenesis in rats reveals therapeutic targets after emergence of first spontaneous seizure
Epileptogenesis is the process by which a normal brain becomes hyperexcitable and capable of generating spontaneous recurrent seizures. The extensive...
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Differential gene expression and miRNA regulatory network in coronary slow flow
Coronary slow flow (CSF) is characterized by slow progression of coronary angiography without epicardial stenosis. The aim of this study was to...
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Integrative bioinformatics analysis of miRNA and mRNA expression profiles identified some potential biomarkers for breast cancer
BackgroundBreast cancer is a common cause of cancer death among women with a complex and heterogeneous picture in histological, molecular and...
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Integrated analysis of diverse cancer types reveals a breast cancer-specific serum miRNA biomarker through relative expression orderings analysis
PurposeSerum microRNA (miRNA) holds great potential as a non-invasive biomarker for diagnosing breast cancer (BrC). However, most diagnostic models...
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Comprehensive Analysis of circRNA, lncRNA, miRNA and mRNA Expression Profiles and Their Competing Endogenous RNA Networks in Hepatitis B Virus-Related Hepatocellular Carcinoma
Pursuing knowledge about circular RNA (circRNA), long non-coding RNA (lncRNA), microRNA (miRNA), and messenger RNA (mRNA) expression profiles and...
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Characterization of the circulating transcriptome expression profile and identification of novel miRNA biomarkers in hypertrophic cardiomyopathy
BackgroundHypertrophic cardiomyopathy (HCM), one of the most common genetic cardiovascular diseases, but cannot be explained by single genetic...