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  1. Almond miRNA Expression and Horticultural Implications

    From the past, till now various improved almond cultivars with desired traits have been introduced through breeding programs based on classical and...
    Marzieh Karimi, Marjan Jafari, ... Behrouz Shiran in The Almond Tree Genome
    Chapter 2023
  2. Determining miRNA Expression Patterns in Xenopus

    Whole-mount in situ hybridization (WISH) is a technique that enables temporal and spatial visualization of RNA molecules in an embryo or whole tissue...
    Marco Antonaci, Alice M. Godden, Grant N. Wheeler in MicroRNA Detection and Target Identification
    Protocol 2023
  3. miRNA Dysregulation in Schizophrenia

    Schizophrenia is a complex neuropsychiatric disorder that alters synapse activity as well as neural circuits. An intricate intracellular network of...
    Mohammed Kaleem, Ritesh Fule, ... Mangesh D. Godbole in Mechanism and Genetic Susceptibility of Neurological Disorders
    Chapter 2024
  4. Altered expression of serum lncRNA CASC2 and miRNA-21-5p in COVID-19 patients

    Infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19) has a high incidence of...

    Shymaa E. Ayoub, Olfat G. Shaker, ... Rania H. Mahmoud in Human Genomics
    Article Open access 12 February 2024
  5. Identification of miRNA expression profile in middle ear cholesteatoma using small RNA-sequencing

    Background

    The present study aims to identify the differential miRNA expression profile in middle ear cholesteatoma and explore their potential roles...

    Mengyao **e, Qi Tang, ... Hua Yang in BMC Medical Genomics
    Article Open access 18 June 2024
  6. Evaluation of miRNA Expression in 3D In Vitro Scaffold-Based Cancer Models

    Accumulating experimental evidence suggests that 3D in vitro cancer models strengthen our understanding of vital processes in the tumor...
    Catherine Murphy, Ciara Gallagher, Olga Piskareva in MicroRNA Profiling
    Protocol 2023
  7. Trimethylamine-N-oxide, a New Risk Factor for Non-alcoholic Fatty Liver Disease Changes the Expression of miRNA-34a, and miRNA-122 in the Fatty Liver Cell Model

    Non-alcoholic fatty liver disease is a multifactorial disorder with complicated pathophysiology ranging from simple steatosis to steatohepatitis and...

    Zhila Bahramirad, Mohammad Raman Moloudi, ... Zakaria Vahabzadeh in Biochemical Genetics
    Article 27 March 2024
  8. Oxford miRNA Gardener

    Genetic traits are a curious question for biological research to elucidate the etiology of pathogenesis and are transmitted from cell to cell,...
    Yoichi Robertus Fujii in The MicroRNA 2000 Transformer
    Chapter 2023
  9. Association between miRNA-145 and miRNA-155 expression in peripheral blood mononuclear cells of patients with multiple sclerosis: a case-control study

    Introduction

    MicroRNAs (miR or miRNA) are short regulatory RNAs, which modulate post-transcriptional gene expression. Dysregulation of these molecules...

    Sepide Ali Ashrafi, Milad Asadi, ... Sheida Shaafi in BMC Neurology
    Article Open access 03 November 2022
  10. miRNA-200c-3p deficiency promotes epithelial-mesenchymal transition in triple-negative breast cancer by activating CRKL expression

    Epithelial-mesenchymal transition (EMT) plays an important role in malignant progression of Triple-negative breast cancer (TNBC). Many studies have...

    Fangfang Nie, Qinfang Zhang, ... Jun Yan in Discover Oncology
    Article Open access 08 May 2024
  11. An Efficient CRISPR-Cas9 Method to Knock Out MiRNA Expression in Xenopus Tropicalis

    In recent years CRISPR-Cas9 knockouts (KO) have become increasingly utilized to study gene function. MicroRNAs (miRNAs) are short noncoding RNAs,...
    Alice M. Godden, Marco Antonaci, Grant N. Wheeler in MicroRNA Detection and Target Identification
    Protocol 2023
  12. Profiling salivary miRNA expression levels in Fanconi anemia patients – a pilot study

    The overarching goal of this study is to predict the risk of develo** oral squamous cell carcinoma (OSCC) in Fanconi anemia (FA) patients. We have...

    Kai Dun Tang, José M. Amenábar, ... Chamindie Punyadeera in Odontology
    Article Open access 17 July 2023
  13. Programmed Evolution by miRNA Memory

    Diseases are deeply implicated in the aberrant expression of microRNA (miRNA) genes. The RNA Wave 2000 dogma consists of four criteria, as first...
    Yoichi Robertus Fujii in The MicroRNA 2000 Transformer
    Chapter 2023
  14. MiRNA Immunity Against Virus and MiRNA Surveillance Against Tumor

    Through the microRNA (miRNA) entangling target sorting/quantum miRNA language plus artificial intelligence (METS/MIRAI) analysis so far, it seems...
    Yoichi Robertus Fujii in The MicroRNA Quantum Code Book
    Chapter 2023
  15. Integrative network analysis of miRNA-mRNA expression profiles during epileptogenesis in rats reveals therapeutic targets after emergence of first spontaneous seizure

    Epileptogenesis is the process by which a normal brain becomes hyperexcitable and capable of generating spontaneous recurrent seizures. The extensive...

    Niraj Khemka, Gareth Morris, ... Niamh M. C. Connolly in Scientific Reports
    Article Open access 03 July 2024
  16. Differential gene expression and miRNA regulatory network in coronary slow flow

    Coronary slow flow (CSF) is characterized by slow progression of coronary angiography without epicardial stenosis. The aim of this study was to...

    Lihua Sun, Juan Wang, ... Shifeng **ng in Scientific Reports
    Article Open access 10 April 2024
  17. Integrative bioinformatics analysis of miRNA and mRNA expression profiles identified some potential biomarkers for breast cancer

    Background

    Breast cancer is a common cause of cancer death among women with a complex and heterogeneous picture in histological, molecular and...

    Seyed Masoud Rezaeijo, Monireh Rezaei, ... Eskandar Taghizadeh in Egyptian Journal of Medical Human Genetics
    Article Open access 19 October 2023
  18. Integrated analysis of diverse cancer types reveals a breast cancer-specific serum miRNA biomarker through relative expression orderings analysis

    Purpose

    Serum microRNA (miRNA) holds great potential as a non-invasive biomarker for diagnosing breast cancer (BrC). However, most diagnostic models...

    Liyuan Ma, Yaru Gao, ... Hongdong Li in Breast Cancer Research and Treatment
    Article Open access 08 January 2024
  19. Comprehensive Analysis of circRNA, lncRNA, miRNA and mRNA Expression Profiles and Their Competing Endogenous RNA Networks in Hepatitis B Virus-Related Hepatocellular Carcinoma

    Pursuing knowledge about circular RNA (circRNA), long non-coding RNA (lncRNA), microRNA (miRNA), and messenger RNA (mRNA) expression profiles and...

    Shaoying Yan, Peng Fu, ... Binbin Gong in Molecular Biotechnology
    Article 27 February 2024
  20. Characterization of the circulating transcriptome expression profile and identification of novel miRNA biomarkers in hypertrophic cardiomyopathy

    Background

    Hypertrophic cardiomyopathy (HCM), one of the most common genetic cardiovascular diseases, but cannot be explained by single genetic...

    Lanyan Guo, Yue Cai, ... Ling Tao in European Journal of Medical Research
    Article Open access 30 June 2023
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