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Systemic therapy and radiotherapy related complications and subsequent hospitalisation rates: a systematic review
BackgroundHospitalisation resulting from complications of systemic therapy and radiotherapy places a substantial burden on the patient, society, and...
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Impact of primary resistance to front-line targeted therapy in metastatic renal cell carcinoma on subsequent immune-checkpoint-inhibition
IntroductionSynergistic effects have been discussed for tyrosine kinase (TKI) and immune checkpoint inhibitors (ICI). Primary resistance to TKI might...
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Pan-cancer assessment of antineoplastic therapy-induced interstitial lung disease in patients receiving subsequent therapy immediately following immune checkpoint blockade therapy
BackgroundDrug-induced interstitial lung disease (DIILD) is a serious adverse event potentially induced by any antineoplastic agent. Whether cancer...
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Continuation of Buprenorphine During Hospitalization and Subsequent Retention in Therapy: an Observational Study in Veterans Administration Hospitals
BackgroundInpatient hospitalization has the potential to disrupt buprenorphine therapy.
ObjectiveAmong patients receiving outpatient buprenorphine...
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Progression patterns, resistant mechanisms and subsequent therapy for ALK-positive NSCLC in the era of second-generation ALK-TKIs
BackgroundIn the era of second-generation ALK tyrosine kinase inhibitors (ALK-TKIs), there was a paucity of data regarding the progression patterns,...
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Arterial Stiffness May Predict Subsequent Cancer Therapy-Related Cardiac Dysfunction in Breast Cancer Patients
Cancer therapy-related cardiac dysfunction (CTRCD) is still a serious problem. Existing risk scores are insufficient for risk classification,...
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Outcomes of surgery and subsequent therapy for central nervous system oligoprogression in EGFR-mutated NSCLC patients
BackgroundOligoprogression is an emerging issue in patients with epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer (NSCLC)....
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Interaction-focused music therapy with cancer-affected children and their significant others: a randomized controlled feasibility study with subsequent intervention (INMUT)
BackgroundPaediatric oncology/haematology patients and their families are confronted with a life-threatening situation for which music therapy can be...
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Efficacy of subsequent treatments in patients with hormone-positive advanced breast cancer who had disease progression under CDK 4/6 inhibitor therapy
BackgroundThere is no standard treatment recommended at category 1 level in international guidelines for subsequent therapy after cyclin-dependent...
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Testosterone replacement therapy is associated with increased odds of Achilles tendon injury and subsequent surgery: a matched retrospective analysis
BackgroundPrescription of testosterone replacement therapy (TRT) has increased in the United States in recent years, and though anabolic steroids...
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Subsequent primary neoplasms after childhood cancer therapy – design and description of the German nested case–control study STATT-SCAR
BackgroundSubsequent primary neoplasms (SPN) are among the most severe late effects and the second most frequent cause of death in childhood cancer...
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Untreated hypogonadism and testosterone replacement therapy in hypogonadal men are associated with a decreased risk of subsequent prostate cancer: a population-based study
We sought to understand the relationship between hypogonadism and testosterone replacement therapy (TRT) in hypogonadal men on the risk of develo**...
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Subsequent treatment for locally advanced non-small-cell lung cancer that progressed after definitive chemoradiotherapy and consolidation therapy with durvalumab: a multicenter retrospective analysis (TOPGAN 2021-02)
PurposeFor patients with locally advanced non-small-cell lung cancer (LA-NSCLC) that progressed after definitive chemoradiotherapy (CRT) and...
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Effective early antiretroviral therapy in perinatal-HIV infection reduces subsequent plasma inflammatory profile
BackgroundThe long-term immunologic effects of antiretroviral therapy (ART) in children with perinatally-acquired HIV (PHIV) have not been fully...
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Reliability of Magseed® marking before neoadjuvant systemic therapy with subsequent contrast-enhanced mammography in patients with non-palpable breast cancer lesions after treatment: the MAGMA study
PurposeTo assess the reliability of excising residual breast cancer lesions after neoadjuvant systemic therapy (NAST) using a previously localized...
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The cycle effect quantified: reduced tumour uptake in subsequent cycles of [177Lu]Lu-HA-DOTATATE during peptide receptor radionuclide therapy
BackgroundClear evidence regarding the effect of reduced tumour accumulation in later peptide receptor radionuclide therapy (PRRT) cycles is lacking....
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Subsequent management and outcomes after first-line PARP inhibitors progression in ovarian cancer patients
ObjectivesThis retrospective study aims to evaluating the subsequent management and outcomes after first-line PARPi progression in Chinese ovarian...
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Clinical evidence for immune-based strategies in early-line multiple myeloma: current challenges in decision-making for subsequent therapy
Almost all patients with multiple myeloma (MM) will eventually develop disease that has relapsed with or become refractory to available treatments...
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Physical Therapy
The role of the physical therapist and physical therapist assistant in providing home care services on an interprofessional team is vital. Physical... -
Real-World Data on Subsequent Therapy for First-Line Osimertinib-Induced Pneumonitis: Safety of EGFR-TKI Rechallenge (Osi-risk Study TORG-TG2101)
BackgroundAlthough osimertinib is a promising therapeutic agent for advanced epidermal growth factor receptor ( EGFR ) mutation-positive lung cancer,...