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Chronic Prurigo Including Prurigo Nodularis: New Insights and Treatments
Chronic prurigo (CPG) is a neuroinflammatory, fibrotic dermatosis that is defined by the presence of chronic pruritus (itch lasting longer than 6...
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Prurigo Nodularis: A Review of IL-31RA Blockade and Other Potential Treatments
Prurigo nodularis (PN), or chronic prurigo, is a distinct disease characterized by the presence of chronic pruritus and multiple localized or...
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A systematic review of interleukin-31 inhibitors in the treatment of prurigo nodularis
BackgroundPrurigo nodularis (PN) is a neuroimmunological skin disease. Severe itching is the most challenging symptom which affects patients’ quality...
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Comprehensive plasma cytokine and chemokine profiling in prurigo nodularis reveals endotypes in Type 2 inflammation
Prurigo nodularis (PN) is a chronic inflammatory skin disease that is associated with variability in peripheral blood eosinophil levels and response...
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Validation of the Peak Pruritus Numerical Rating Scale as a Patient-Reported Outcome Measure in Prurigo Nodularis
IntroductionValidated patient report tools for quantifying patient experiences of itch in prurigo nodularis (PN) are limited. This study aimed to...
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The Sleep Disturbance Numerical Rating Scale: Content Validity, Psychometric Validation, and Meaningful Within-Patient Change in Prurigo Nodularis
IntroductionSleep is often disturbed in patients with prurigo nodularis (PN). To address the lack of validated patient-reported outcome (PRO)...
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Therapie der chronischen Prurigo: Update und Perspektive
BackgroundDespite the high burden in patients with chronic prurigo (CPG), the first and so far only approved systemic therapy for this disease,...
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Dupilumab in patients with prurigo nodularis: two randomized, double-blind, placebo-controlled phase 3 trials
Prurigo nodularis (PN) is a chronic inflammatory skin disease with intensely pruritic nodules. The LIBERTY-PN PRIME and PRIME2 phase 3 trials...
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Prurigo
Prurigo represents a group of dermatoses characterized by intense pruritus and papular and papular-vesicular lesions. It can be acute (when resulting... -
Prurigo Nodularis onset during secukinumab treatment of psoriasis: a case report
BackgroundSecukinumab has been approved by the U.S. FDA and the European Medicines Agency for the treatment of moderate-to-severe plaque psoriasis...
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Effectiveness of Dupilumab for Chronic Prurigo in Chinese Patients: A Real-World Case Series Study
BackgroundTreatment of chronic prurigo (CPG) is challenging. As an antagonist of IL-4R, dupilumab has shown effectiveness in treating CPG in several...
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Eine unerwartete Entdeckung bei einer Patientin mit chronischer Prurigo
We report on a 61-year-old woman with a sudden onset of itching and nodules on the skin for the last year. Chronic prurigo (CPG) was diagnosed. An...
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Update zur Therapie der chronischen Prurigo
Chronic prurigo is an inflammatory dermatosis defined by the presence of chronic pruritus and single to multiple symmetrically distributed...