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Investigation of micropollutants in household waste fractions processed by anaerobic digestion: target analysis, suspect- and non-target screening
Household waste represents a major source of energy, nutrients, and recyclable material. In order to exploit benefits and avoid hazards in the...
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NORMAN guidance on suspect and non-target screening in environmental monitoring
Increasing production and use of chemicals and awareness of their impact on ecosystems and humans has led to large interest for broadening the...
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Beyond target chemicals: updating the NORMAN prioritisation scheme to support the EU chemicals strategy with semi-quantitative suspect/non-target screening data
BackgroundPrioritisation of chemical pollutants is a major challenge for environmental managers and decision-makers alike, which is essential to help...
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Non-target screening of surface water samples to identify exposome-related pollutants: a case study from Luxembourg
BackgroundNon-target screening of surface water samples collected over an extended period can reveal interesting temporal patterns in...
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Non-target Screening Analysis of “New” Persistent Organic Pollutants in the Far Eastern Seas
A non-target screening analysis has been conducted to search for persistent organic pollutants (POPs) “new” to the Far Eastern region for the first... -
From target analysis to suspect and non-target screening of endocrine-disrupting compounds in human urine
In the present work, a target analysis method for simultaneously determining 24 diverse endocrine-disrupting compounds (EDCs) in urine...
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Non-target screening in water analysis: recent trends of data evaluation, quality assurance, and their future perspectives
This trend article provides an overview of recent advancements in Non-Target Screening (NTS) for water quality assessment, focusing on new methods in...
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A stochastic approach for parameter optimization of feature detection algorithms for non-target screening in mass spectrometry
Feature detection plays a crucial role in non-target screening (NTS), requiring careful selection of algorithm parameters to minimize false positive...
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Critical review on data processing algorithms in non-target screening: challenges and opportunities to improve result comparability
Non-target screening (NTS) is a powerful environmental and analytical chemistry approach for detecting and identifying unknown compounds in complex...
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Screening Non-neutralizing Anti-idiotype Antibodies Against a Drug Candidate for Total Pharmacokinetic and Target Engagement Assay
Non-neutralizing anti-idiotype antibodies against a therapeutic monoclonal antibody (mAb) play a crucial role in the creation of total...
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Quality Assurance and Quality Control (QA/QC) for High-Resolution Mass Spectrometry (HRMS) Non-target Screening Methods
High-resolution mass spectrometry (HRMS) methods applying suspect screening and non-target analysis (NTA) approaches are becoming more commonly... -
Non-target Screening Using LC-HRMS: Fundamentals, Key Aspects, and Application to Identify Transformation Products of Organic Contaminants in the Environment
Non-target screening (NTS) approaches in combination with high-resolution mass spectrometry (HRMS) instrumental arrays have the potential to... -
Non-target estrogenic screening of 60 pesticides, six plant protection products, and tomato, grape, and wine samples by planar chromatography combined with the planar yeast estrogen screen bioassay
For non-target residue analysis of xenoestrogens in food, sophisticated chromatographic–mass spectrometric techniques lack in biological effect...
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Identification of the estrogen-active compounds via integrating effect-directed analysis and non-target screening in soils of the northeastern China
BackgroundThe gaps between estrogenic effect and its effect-active compounds exist frequently due to a large number of compounds that have been...
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Bone morphogenetic protein 2 is a new molecular target linked to non-alcoholic fatty liver disease with potential value as non-invasive screening tool
BackgroundNon-alcoholic fatty liver disease (NAFLD) is the commonest cause of chronic liver disease worldwide, being non-alcoholic steatohepatitis...
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Screening
Screening, sometimes termed “secondary prevention,” is one of the major components of disease control. It is particularly relevant for the control of... -
Identifying Emerging Pollutants Using Non-target or Wide-Screening Liquid Chromatography-Mass Spectrometry
In this chapter we review the available data on the application of non-targeted high-resolution mass spectrometry (HRMS) analysis to identify a wide... -
Transcriptomic and metabolomic analysis provides insight into imazethapyr toxicity to non-target plants
Imazethapyr is a widely used imidazolinone herbicide worldwide, and its potential adverse effects on non-target plants have raised concerns....
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Target, suspect and non-target screening analysis from wastewater treatment plant effluents to drinking water using collision cross section values as additional identification criterion
The anthropogenic entry of organic micropollutants into the aquatic environment leads to a potential risk for drinking water resources and the...
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Suspect and non-target screening of chemicals in clothing textiles by reversed-phase liquid chromatography/hybrid quadrupole-Orbitrap mass spectrometry
The global manufacturing of clothing is usually composed of multistep processes, which include a large number of chemicals. However, there is...