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1. Therapeutic effect of microRNA-21 on differentially expressed hub genes in gastric cancer based on systems biology

   Gastric cancer (GC) is a leading cause of mortality for many people. Cancer’s initiating factors are poorly understood. miR-21 has a crucial function...

   Hesam Ghafouri Kalajahi, AmirHossein Yari, ... Ahad Mokhtarzadeh in Scientific Reports

   Article Open access 11 December 2023
   

2. Loss of microRNA-21 protects against acetaminophen-induced hepatotoxicity in mice

   Acetaminophen (APAP)-induced Acute Liver Failure (ALF) is recognized as the most common cause of ALF in Western societies. APAP-induced ALF is...

   Alexandra M. Huffman, Maryam Syed, ... Damian G. Romero in Archives of Toxicology

   Article 14 May 2023
   

3. The mechanisms of MicroRNA 21 in premature ovarian insufficiency mice with mesenchymal stem cells transplantation

   Umbilical cord-derived mesenchymal stem cell (UCMSC) transplantation has been deeply explored for premature ovarian insufficiency (POI) disease....

   Na Yin, Chao Luo, ... Cai** Mao in Journal of Ovarian Research

   Article Open access 04 April 2024
   

4. A Prussian blue nanoparticles-based fluorescent nanoprobe for monitoring microRNA-92a and microRNA-21

   Since microRNA-92a (miR-92a) and microRNA-21 (miR-21) are crucial biomarkers for colorectal cancer (CRC), monitoring miR-92a and miR-21 in serum is...

   Yao Li, Ren Guo, ... Huiyun Wu in Analytical Sciences

   Article 01 March 2022
   

5. Simulation of Highly Sensitive Multi-Core-Satellite Plasmonic Structures for Detection of Gastric Cancer Agent MicroRNA-21 Using Modified Discrete Dipole Approximation

   Using the modified discrete dipole approximation (DDA) method, the absorption spectrum of the multi-core-satellite structures (which are formed by...

   Araz Siabi-Garjan, Solmaz Kia, Sharareh Mirzaee in Plasmonics

   Article 03 January 2024
   

6. Evaluation of serum MicroRNA 21, MicroRNA 192 and serum TGFβ1 in type 2 diabetes mellitus patients and their relation to diabetic nephropathy

   Background

   Diabetic nephropathy (DN) is a frequent and long-lasting microvascular consequence that has an established connection with diabetes. It...

   Jumana Gamal Abou Eleila, Amal Abdel Wahab Mohamed, ... Hadeel Mohammad Elhanafi in Egyptian Journal of Medical Human Genetics

   Article Open access 08 July 2024
   

7. Carbon dots hybrid for dual fluorescent detection of microRNA-21 integrated bioimaging of MCF-7 using a microfluidic platform

   Background

   MicroRNAs have short sequences of 20 ~ 25-nucleotides which are similar among family members and play crucial regulatory roles in numerous...

   Somayeh Mohammadi, Abdollah Salimi, ... Kamran Mansouri in Journal of Nanobiotechnology

   Article Open access 08 February 2022
   

8. MicroRNA-21 modulates brown adipose tissue adipogenesis and thermogenesis in a mouse model of polycystic ovary syndrome

   Background

   Polycystic ovary syndrome (PCOS), the most common endocrine disorder in premenopausal women, is associated with increased obesity,...

   Samar Rezq, Alexandra M. Huffman, ... Damian G. Romero in Biology of Sex Differences

   Article Open access 10 July 2024
   

9. A simple “signal off–on” fluorescence nanoplatform for the label-free quantification of exosome-derived microRNA-21 in lung cancer plasma

   A simple nanoplatform based on molybdenum disulfide (MoS ₂ ) nanosheets, a fluorescence quencher (signal off), and a hybridization chain reaction (HCR)...

   **lan Wei, Sitian He, ... Yongjun Wu in Microchimica Acta

   Article 29 October 2021
   

10. MicroRNA -21 expression as an auxiliary diagnostic biomarker of acute brucellosis

    Background

    This study aimed to measure the expression levels of peripheral blood miRNAs in brucellosis and their involvement in the different phases...

    Mahsa Rezaeepoor, Fariba Keramat, ... Ghasem Solgi in Molecular Biology Reports

    Article 01 February 2024
    

11. MicroRNA miR-21 Decreases Post-stroke Brain Damage in Rodents

    Due to their role in controlling translation, microRNAs emerged as novel therapeutic targets to modulate post-stroke outcomes. We previously reported...

    Mary S. Lopez, Kahlilia C. Morris-Blanco, ... Raghu Vemuganti in Translational Stroke Research

    Article 18 November 2021
    

12. Cancer-associated fibroblast-derived exosome microRNA-21 promotes angiogenesis in multiple myeloma

    Multiple myeloma (MM) is the second most common hematological malignancy, and angiogenesis determines its progression. In the tumor microenvironment,...

    Sun Miaomiao, Wang **aoqian, ... Chen Kuisheng in Scientific Reports

    Article Open access 14 June 2023
    

13. A microRNA-21-responsive doxorubicin-releasing sticky-flare for synergistic anticancer with silencing of microRNA and chemotherapy

    A sticky-flare gold nanoparticle probe (AuNP-probe) is designed by the combination of locked nucleic acid functionalized silencing of microRNA...

    Min Hong, Hongxiao Sun, ... Weihong Tan in Science China Chemistry

    Article 15 April 2021
    

14. Role of MicroRNA-21 in Prostate Cancer Progression and Metastasis: Molecular Mechanisms to Therapeutic Targets

    The role of noncoding RNA has made remarkable progress in understanding progression, metastasis, and metastatic castration-resistant prostate cancer...

    Vipendra Kumar Singh, Naina Rajak, ... Neha Garg in Annals of Surgical Oncology

    Article 17 May 2024
    

15. MicroRNA-21 is immunosuppressive and pro-metastatic via separate mechanisms

    MiR-21 was identified as a gene whose expression correlated with the extent of metastasis of murine mammary tumours. Since miR-21 is recognised as...

    Lap Hing Chi, Ryan S. N. Cross, ... Robin L. Anderson in Oncogenesis

    Article Open access 11 July 2022
    

16. MicroRNA-21 promotes head and neck squamous cell carcinoma (HNSCC) induced transition of bone marrow mesenchymal stem cells to cancer-associated fibroblasts

    Background

    Most patients diagnosed with head and neck tumor will present with locally advanced disease, requiring multimodality therapy. Bone...

    Hao Wang, Zhengyu Zhou, ... Jun Wang in BMC Cancer

    Article Open access 22 November 2023
    

17. Aberrant Methylation of 21 MicroRNA Genes in Breast Cancer: Sets of Genes Associated with Progression and a System of Markers for Predicting Metastasis

    Systemic analysis of the relationship between the levels of methylation of 21 microRNA genes and the parameters of breast cancer progression was...

    V. I. Loginov, A. M. Burdennyy, ... E. A. Braga in Bulletin of Experimental Biology and Medicine

    Article 18 November 2021

18. Fluorescent detection of microRNA-21 in MCF-7 cells based on multifunctional gold nanorods and the integration of chemotherapy and phototherapy

    MicroRNA-21 is an important biomarker of tumor early prediction and metastasis, and its accurate detection is of great significance for tumor...

    Yan Gong, Wei Yuan, ... Caifeng Ding in Microchimica Acta

    Article 14 July 2021
    

19. Serum MicroRNA 21 and Tumour Marker in Oesophagus Cancer: Correspondence

    Rujittika Mungmunpuntipantip, Viroj Wiwanitkit in Indian Journal of Surgical Oncology

    Article 25 April 2022

20. A PRISMA meta-analysis for diagnostic value of microRNA-21 in head and neck squamous cell carcinoma along with bioinformatics research

    Objectives

    The use of miR-21 expression remains vague in diagnosis of head and neck squamous cell carcinoma (HNSCC). This study aimed to...

    Chen-xi Li, Ying Su, ... Hua-rong Zhao in Oral and Maxillofacial Surgery

    Article 01 December 2023