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Attenuation of A(H7N9) influenza virus infection in mice exposed to cigarette smoke
Influenza A(H7N9) virus showed high pathogenicity in humans when it emerged in 2013. Cigarette smoke (CS) causes pulmonary diseases including...
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Computational Studies of Phytochemicals from Allium Sativum with H7N9 Subtype in Avian Influenza
Allium sativum or garlic is a medicinal plant that is reported for its applications in many biological activities, such as its antiviral,... -
Influenza H7N9 virus disrupts the monolayer human brain microvascular endothelial cells barrier in vitro
Influenza H7N9 virus causes human infections with about 40% case fatality rate. The severe cases usually present with pneumonia; however, some...
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Reintroduction of highly pathogenic avian influenza A H7N9 virus in southwestern China
Highly pathogenic (HP) avian influenza A H7N9 virus has emerged in China since 2016. In recent years, it has been most prevalent in northern China....
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A protective measles virus-derived vaccine inducing long-lasting immune responses against influenza A virus H7N9
A novel Influenza A virus (subtype H7N9) emerged in spring 2013 and caused considerable mortality in zoonotically infected patients. To be prepared...
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H7N9 avian influenza virus infection in men is associated with testosterone depletion
Human infections with H7N9 avian influenza A virus that emerged in East China in 2013 and caused high morbidity rates were more frequently detected...
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A dominant internal gene cassette of high pathogenicity avian influenza H7N9 virus raised since 2018
The zoonotic H7N9 avian influenza virus emerged with the H9N2-origin internal gene cassette. Previous studies have reported that genetic...
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Human neutralizing antibodies target a conserved lateral patch on H7N9 hemagglutinin head
Avian influenza A virus H7N9 causes severe human infections with >30% fatality. Currently, there is no H7N9-specific prevention or treatment for...
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Tripartite motif-containing protein 46 accelerates influenza A H7N9 virus infection by promoting K48-linked ubiquitination of TBK1
BackgroundAvian influenza A H7N9 emerged in 2013, threatening public health and causing acute respiratory distress syndrome, and even death, in the...
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Designing a multi-epitope vaccine to provoke the robust immune response against influenza A H7N9
A new strain of Influenza A Virus (IAV), so-called "H7N9 Avian Influenza", is the first strain of this virus in which a human is infected by...
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A synthetic TLR4 agonist significantly increases humoral immune responses and the protective ability of an MDCK-cell-derived inactivated H7N9 vaccine in mice
Antigenically divergent H7N9 viruses pose a potential threat to public health, with the poor immunogenicity of candidate H7N9 vaccines demonstrated...
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H7N9 Avian Influenza in Human
H7N9 avian influenza in humans can be categorized into three types including the asymptomatic (the inapparent), the mild, and the severe. The patient... -
Screening and identification of specific cluster miRNAs in N2a cells infected by H7N9 virus
This study aims to screen and identify specific cluster miRNAs of H7N9 virus-infected N2a cells and explore the possible pathogenesis of these...
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Amino acid mutations PB1-V719M and PA-N444D combined with PB2-627K contribute to the pathogenicity of H7N9 in mice
H7N9 subtype avian influenza viruses (AIVs) cause 1567 human infections and have high mortality, posing a significant threat to public health....
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Avian influenza A (H7N9) virus: from low pathogenic to highly pathogenic
The avian influenza A (H7N9) virus is a zoonotic virus that is closely associated with live poultry markets. It has caused infections in humans in...
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Influenza in Travellers
Influenza is a widespread respiratory infection that can have serious implications for travellers. Those going overseas can undertake a range of... -
Zoonoses: Avian Influenza, Borna Disease and COVID-19
Avian influenza is a major viral disease of wild birds and poultry in livestock and is caused by influenza A viruses. Infections result in major... -
The viral distribution and pathological characteristics of BALB/c mice infected with highly pathogenic Influenza H7N9 virus
BackgroundThe highly pathogenic Influenza H7N9 virus is believed to cause multiple organ infections. However, there have been few systematic animal...
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Molecular epidemiologic characteristics of hemagglutinin from five waves of avian influenza A (H7N9) virus infection, from 2013 to 2017, in Zhejiang Province, China
There have been five waves of influenza A (H7N9) epidemics in Zhejiang Province between 2013 and 2017. Although the epidemiological characteristics...
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Mink infection with influenza A viruses: an ignored intermediate host?
Continuously emergence of human infection with avian influenza A virus poses persistent threat to public health, as illustrated in zoonotic H5N1/6...