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A programmable protease-based protein secretion platform for therapeutic applications
Cell-based therapies represent potent enabling technologies in biomedical science. However, current genetic control systems for engineered-cell...
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Specific interactions between the alkaline protease of P. aeruginosa and its natural peptide inhibitor: ab initio molecular simulations
Alkaline protease aeruginolysin (APR) is an important virulence factor in the evasion of the immune system by Pseudomonas aeruginosa (P. aeruginosa) ....
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Isolation, identification, and optimization of the fibrinolytic protease-producing strains
Cardiovascular complications due to thrombosis have become one of the main causes of death worldwide. The high cost and undesirable side effects of...
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Comparative Studies of the Characteristics of Two Alkaline Proteases from Haloalkaliphilic bacterium D-15-9 and Oceanobacillus onchorynchii Mi-10-54
AbstractThe study describes purification and characterization of two alkaline proteases in comparative manner from haloalkaliphilic bacteria obtained...
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On the Postembryonic Activity of Alkaline Phosphatase in Different Tissues in Broilers
Alkaline phosphatase (AP) is a wide-spread enzyme presenting in blood and other biological liquids and tissues; its activities easily react to...
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A green chemistry approach through oxidative agent in combination with protease for dehairing: an enhanced path towards sustainability
The dehairing is one of the essential steps in the leather-making operation where the hair is removed using lime and sodium sulphide by the...
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Plasma membrane-localized H+-ATPase OsAHA3 functions in saline–alkaline stress tolerance in rice
Key messageA novel function of plasma membrane-localized H + -ATPase, OsAHA3, was identified in rice, which is involved in saline–alkaline tolerance...
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Elucidating the role of artificial diet on protease enzyme activity in larval midgut of Helicoverpa armigera as influenced by modification of artificial diet by Cry1Ac toxin
Digestive midgut protease activity in fifth instar larvae (L 5 ) of Helicoverpa armigera was investigated under controlled conditions, where, an...
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Protease Production by Bacteria Isolated from Laguna Chiar Khota, Potosi-Bolivia, for Protein Hydrolysates Production
Proteases are a large and diverse group of enzymes widely used in different industrial processes. Extreme environments support a biodiversity capable...
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Key mechanism of enzymatic dehairing technology for leather-making: permeation behaviors of protease into animal hide and the mechanism of charge regulation
Enzymes have been widely used as alternatives to conventional chemicals in cleaner leather processes due to their advantages of meeting increasing...
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Mass Multiplication, Production Cost Analysis and Marketing of Protease
Proteases are widely distributed enzymes that play an important role in both synthesis and breakdown. The catalytic characteristics of proteases have...
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Homology modeling and heterologous expression of highly alkaline subtilisin-like serine protease from Bacillus halodurans C-125
Here we report heterologous expression, enzymatic characterization and structure homology modeling of a subtilisin-like alkaline serine protease...
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Structural basis of the alkaline pH-dependent activation of insulin receptor-related receptor
The insulin receptor (IR) family is a subfamily of receptor tyrosine kinases that controls metabolic homeostasis and cell growth. Distinct from IR...
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Recent advances in the production, properties and applications of haloextremozymes protease and lipase from haloarchaea
Proteases and lipases are significant groups of enzymes for commercialization at the global level. Earlier, the industries depended on mesophilic...
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Heterologous expression, purification, and proteomic characterization of a 37 kDa pupal gut serine protease from Bombyx mori in Escherichia coli
Recently, there has been a growing interest in exploring the potential of insect proteases for industrial applications, owing to their versatile...
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Eco-Friendly Substitution in Laundry Detergent Compositions by Enzymatic Additives
Because of the ecological problems related to the use of chemical products, the new detergents have progressed to become more eco-friendly....
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Improving the specific activity and stability of alkaline pectinase PEL3 through SpyTag/SpyCatcher cyclization
ObjectivesPEL3, an alkaline pectinase, exhibited the highest activity among documented alkaline pectate lyases reported in our early study....
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Identification of Protease Enzymes Involved in Biocontrol Activity
Many microorganisms have plant growth-promoting activity and biocontrol activity, which is mainly imparted by their metabolic potential to the...
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Comparative analysis of reconstructed ancestral proteins with their extant counterparts suggests primitive life had an alkaline habitat
To understand the origin and early evolution of life it is crucial to establish characteristics of the primordial environment that facilitated the...
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Production, Partial Purification and Optimization of Oilseed-Based Protease and its Application as an Efficient Eco-Friendly Alternative for Destaining and Dehairing Process
Proteases are a group of industrially valuable enzymes with significant demand owing to their diverse and extensive range of biotechnological...
