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  1. Clinical characteristics and factors associated with survival rate of patients with non-muscle invasive bladder cancer attending at a Tertiary Hospital in Somalia

    Background

    A few studies regarding the epidemiology and risk factors of Non-muscle Invasive Bladder Cancer (NMIBC) are reported from Sub-Saharan...

    Abdikarim Hussein Mohamed, Khaled Ali Mohamed, ... Mohamed Abdikarim Nur-amin in BMC Cancer
    Article Open access 14 July 2024
  2. PIM1/NF-κB/CCL2 blockade enhances anti-PD-1 therapy response by modulating macrophage infiltration and polarization in tumor microenvironment of NSCLC

    Elevated infiltration of tumor-associated macrophages (TAMs) drives tumor progression and correlates with poor prognosis for various tumor types. Our...

    **uqiong Chen, **g Zhou, ... Richeng Jiang in Oncogene
    Article 14 July 2024
  3. PHF6 suppresses self-renewal of leukemic stem cells in AML

    Acute myeloid leukemia is characterized by uncontrolled proliferation of self-renewing myeloid progenitors accompanied by a differentiation arrest....

    Sapana S. Jalnapurkar, Aishwarya S. Pawar, ... Vikram R. Paralkar in Leukemia
    Article Open access 14 July 2024
  4. Hemostasis and complement in allogeneic hematopoietic stem cell transplantation: clinical significance of two interactive systems

    Hematopoietic stem cell transplantation (HCT) represents a curative treatment option for certain malignant and nonmalignant hematological diseases....

    Dimitrios A. Tsakiris, Eleni Gavriilaki, ... Sara C. Meyer in Bone Marrow Transplantation
    Article Open access 14 July 2024
  5. Identifying early symptoms associated with a diagnosis of childhood, adolescent and young adult cancers: a population-based nested case-control study

    Background

    Childhood, teenage and young adult (CTYA, 0–24 years) cancers are rare and diverse, making timely diagnosis challenging. We aim to explore...

    D. Saatci, J. Oke, ... J. Hippisley-Cox in British Journal of Cancer
    Article Open access 14 July 2024
  6. Outcomes of patients undergoing third hematopoietic cell transplantation for hematologic malignancies

    With advancements in novel therapeutics, it is unclear whether third hematopoietic cell transplantation (HCT3) has a place in the treatment of...

    Emily R. Cox, Corinne Summers, ... Monica S. Thakar in Annals of Hematology
    Article 14 July 2024
  7. m1A demethylase Alkbh3 regulates neurogenesis through m1A demethylation of Mmp15 mRNA

    Background

    N 1 -Methyladenosine (m 1 A) is an abundant modification of transcripts regulating mRNA structure and translation efficiency. However, the...

    Huan Wang, Linjie **e, ... Aiguo Xuan in Cell & Bioscience
    Article Open access 14 July 2024
  8. Trametinib for a child with refractory Rosai–Dorfman–Destombes disease harboring a novel somatic mutation in MAP2K1

    Rosai–Dorfman–Destombes disease (RDD) is a rare histiocytosis characterized by accumulation of S100 + , CD68 + , and CD1a- histiocytes, with...

    Yuichi Taneyama, Akira Morimoto, ... Sana Yokoi in International Journal of Hematology
    Article 14 July 2024
  9. Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition

    SF3B1 mutations frequently occur in cancer yet lack targeted therapies. Clinical trials of XPO1 inhibitors, selinexor and eltanexor, in high-risk...

    Sana Chaudhry, Felipe Beckedorff, ... Justin Taylor in Leukemia
    Article Open access 13 July 2024
  10. SUMOylation of nuclear receptor Nor1/NR4A3 coordinates microtubule cytoskeletal dynamics and stability in neuronal cells

    Background

    Nor1/NR4A3 is a member of the NR4A subfamily of nuclear receptors that play essential roles in regulating gene expression related to...

    Jonathan Gagnon, Véronique Caron, André Tremblay in Cell & Bioscience
    Article Open access 13 July 2024
  11. Platelet-Rich Plasma Promotes the Expansion of Human Myoblasts and Favors the In Vitro Generation of Human Muscle Reserve Cells in a Deeper State of Quiescence

    Stem cell therapy holds significant potential for skeletal muscle repair, with in vitro-generated human muscle reserve cells (MuRCs) emerging as a...

    Axel Tollance, Alexandre Prola, ... Thomas Laumonier in Stem Cell Reviews and Reports
    Article Open access 13 July 2024
  12. Death anxiety among caregivers of patients with advanced cancer: a cross-sectional survey

    Purpose

    This study aimed to investigate death anxiety (DA) in caregivers of patients with advanced cancer and identify associated factors in the...

    Li Ying, Duan Yuyu, ... Zhou Zhihuan in Supportive Care in Cancer
    Article 13 July 2024
  13. The Angiogenic Repertoire of Stem Cell Extracellular Vesicles: Demystifying the Molecular Underpinnings for Wound Healing Applications

    Stem cells-derived extracellular vesicles (SC-EVs) have emerged as promising therapeutic agents for wound repair, recapitulating the biological...

    Shuoyuan Liu, Huayuan Zhao, ... Zhenbing Chen in Stem Cell Reviews and Reports
    Article 13 July 2024
  14. Carbon-ion radiotherapy alone vs. standard dose photon radiation with carbon-ion radiotherapy boost for high-grade gliomas: a retrospective study

    Background

    This study aimed to compare the survival outcome and side effects in patients with primary high-grade glioma (HGG) who received carbon ion...

    **aoJun Li, YanShan Zhang, ... Faxin Wen in BMC Cancer
    Article Open access 13 July 2024
  15. Safety and Efficacy of Covered Self-Expandable Metallic Stent for Choledochojejunal Anastomotic Stricture: A Multi-Center Retrospective Cohort Study

    Background

    Benign choledochojejunal anastomotic stricture (CJS) is a complication of pancreaticoduodenectomy and choledochojejunostomy. Typically...

    Yuhei Iwasa, Takuji Iwashita, ... Masahito Shimizu in Digestive Diseases and Sciences
    Article 13 July 2024
  16. Deep learning model based on endoscopic images predicting treatment response in locally advanced rectal cancer undergo neoadjuvant chemoradiotherapy: a multicenter study

    Purpose

    Neoadjuvant chemoradiotherapy has been the standard practice for patients with locally advanced rectal cancer. However, the treatment response...

    Junhao Zhang, Ruiqing Liu, ... Yun Lu in Journal of Cancer Research and Clinical Oncology
    Article Open access 13 July 2024
  17. Peripheral blood immune parameters, response, and adverse events after neoadjuvant chemotherapy plus durvalumab in early-stage triple-negative breast cancer

    Purpose

    We evaluated T- and B-cell receptor (TCR and BCR) repertoire diversity and 38 serum cytokines in pre- and post-treatment peripheral blood of...

    Julia Foldi, Kim R. M. Blenman, ... Lajos Pusztai in Breast Cancer Research and Treatment
    Article 13 July 2024
  18. Association of oral mucositis induced by anthracycline-cyclophosphamide and subsequent docetaxel treatment for perioperative breast cancer

    Purpose

    Anthracycline-cyclophosphamide followed by docetaxel-containing chemotherapy is effective for perioperative breast cancer treatment. However,...

    Yoshitaka Saito, Yoh Takekuma, ... Mitsuru Sugawara in Supportive Care in Cancer
    Article 13 July 2024
  19. Hyponatremia Is Associated with Mortality in Acute Pancreatitis Patients

    Background

    Disorders of serum sodium are common among general patients and are associated with poor outcomes. The prognostic value of serum sodium...

    Liqing Song, Wen Tang, ... Ying Xu in Digestive Diseases and Sciences
    Article 13 July 2024
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