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Universal Prevention of Dementia in Italy: A Document Analysis of the 21 Italian Regional Prevention Plans
BackgroundUp to 40% of dementia cases are theoretically avoidable and population-level interventions (i.e., universal prevention) are a key component...
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No Association Found: Adverse Childhood Experiences and Cognitive Impairment in Older Australian Adults
ObjectiveThis study aimed to investigate the relationship between childhood adversity and cognitive impairment in older adults.
Methods ...
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Current Topics Regarding the Function of the Medial Temporal Lobe Memory System
The first clear insight that the medial temporal lobe of the human brain was in fact a system of anatomically connected structures that were...
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Glycogenolysis-Induced Astrocytic Ser**1 Expression Regulates Neuroinflammatory Effects on Hippocampal neuron
The bacterial pathogen, lipopolysaccharide (LPS), elicits microglial response and induces cytokine secretion that subsequently activates astrocytes....
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Filetlappentransfer als Alternative zu konventionellen Amputationen der unteren Extremität
BackgroundThe fitting of a prosthesis after lower limb amputation is associated with several challenges. Skeletal stump-prosthesis interfaces and...
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Spinal dementia: Don’t miss it, it’s treatable
Background & purposeAround 5% of dementia patients have a treatable cause. To estimate the prevalence of two rare diseases, in which the treatable...
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Oxygen uptake efficiency plateau is unaffected by fitness level - the NOODLE study
BackgroundEndurance athletes (EA) are an emerging population of focus for cardiovascular health. The oxygen uptake efficiency plateau (OUEP) is the...
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Magnetic Seizure Therapy in Management of Depression: A Narrative Review
Purpose of ReviewThis review aims to discuss historical aspects, mechanism of action, safety and efficacy, response predictors, and Magnetic Seizure...
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Intraoperative MRI without an intraoperative MRI suite: a workflow for glial tumor surgery
BackgroundIntraoperative MRI (iMRI) has emerged as a useful tool in glioma surgery to safely improve the extent of resection. However, iMRI requires...
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Partial coil embolization before surgical clip** of ruptured intracranial aneurysms
ObjectiveIntraoperative rupture (IOR) is the most common adverse event encountered during surgical clip obliteration of ruptured intracranial...
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Radiomics model based on dual-energy CT can determine the source of thrombus in strokes with middle cerebral artery occlusion
PurposeTo develop thrombus radiomics models based on dual-energy CT (DECT) for predicting etiologic cause of stroke.
MethodsWe retrospectively...
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A clinically compatible in vitro drug-screening platform identifies therapeutic vulnerabilities in primary cultures of brain metastases
PurposeBrain metastases represent the most common intracranial tumors in adults and are associated with a poor prognosis. We used a personalized in...
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Exploratory Mass Spectrometry of Cerebrospinal Fluid from Persons with Autopsy-Confirmed LATE-NC
Common neuropathologies associated with dementia include Alzheimer’s disease neuropathologic change (ADNC) and limbic-predominant age-related TDP-43...
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Assessment of the importance of sleep quality and the effects of deprivation on Sudanese healthcare professionals amidst conflict in Sudan
BackgroundQuality sleep is vital for well-being, especially for healthcare workers facing high risks of fatigue and burnout. Sleep deprivation...
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Fibroblast growth factor receptor 4 deficiency in macrophages aggravates experimental colitis by promoting M1-polarization
Objective and designCompelling evidence indicates that dysregulated macrophages may play a key role in driving inflammation in inflammatory bowel...
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Neurological and Psychiatric Clinical Manifestations of Sjögren Syndrome
Purpose of ReviewSjögren Syndrome is a systemic autoimmune disorder that presents mainly with sicca symptoms, but frequently affects other body...
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Effectiveness of personalized rehabilitation in adults suffering from persistent concussion symptoms as compared to usual care: a randomized control trial protocol
BackgroundSymptoms reported by patients who sustain a concussion are non-specific. As such, clinicians are better able to manage patients when a...