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Tirzepatide Improved Health-Related Quality of Life Compared with Insulin Lispro in Basal Insulin-Treated Adults with Type 2 Diabetes and Inadequate Glycaemic Control: A Randomised Controlled Phase 3b Trial (SURPASS-6)
IntroductionPatients with type 2 diabetes (T2D) who require intensification of basal insulin therapy need treatment options that can improve their...
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Clinical management protocols for community pharmacist-led management of urinary tract infections: a review of the grey literature and quality appraisal
BackgroundPharmacist-led management of urinary tract infections has been introduced as a service in the United Kingdom, Canada, United States of...
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Association of Changes in A1C Following Continuous Glucose Monitoring Acquisition in People with Sub-Optimally Treated Type 2 Diabetes Taking GLP-1 RA Therapy
IntroductionBoth glucagon-like peptide-1 receptor agonists (GLP-1 RA) and continuous glucose monitoring (CGM) improve glycemia in patients with type...
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Early colonic-preparation and salvage laparoscopic appendectomy (ECSLA)- innovative protocol for the management of magnets ingestion
BackgroundIngestion of magnets carries risks for significant morbidity. We propose a new protocol designed to reduce the need for surgery, shorten...
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A One Health framework for exploring zoonotic interactions demonstrated through a case study
The eco-epidemiology of zoonoses is often oversimplified to host-pathogen interactions while findings derived from global datasets are rarely...
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Sex-specific role of high-fat diet and stress on behavior, energy metabolism, and the ventromedial hypothalamus
BackgroundScientific evidence highlights the influence of biological sex on the relationship between stress and metabolic dysfunctions. However,...
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The transition from tube feeding to oral feeding algorithm in preterm infants: case-control study
BackgroundOral feeding is a complex sensorimotor process influenced by many variables, making it challenging for healthcare providers to introduce...
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A buzzword, a “win-win”, or a signal towards the future of agriculture? A critical analysis of regenerative agriculture
As the term regenerative agriculture caught fire in public discourse around 2019, it was promptly labelled a buzzword. While the buzzword accusation...
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Single-cell multiomics reveals ENL mutation perturbs kidney developmental trajectory by rewiring gene regulatory landscape
How disruptions to normal cell differentiation link to tumorigenesis remains incompletely understood. Wilms tumor, an embryonal tumor associated with...
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Sustained North Atlantic warming drove anomalously intense MIS 11c interglacial
The Marine Isotope Stage (MIS) 11c interglacial and its preceding glacial termination represent an enigmatically intense climate response to...
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Utility of the web excision with pre-membranous incision for congenital intestinal atresia-type I and stenosis
PurposeThis study analyzed the efficacy of web excision combined with a pre-membranous incision on the dilated proximal segment for congenital...
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Relation between attitudes towards pornography consumption, peer sexual behaviors and attitudes towards premarital sex among the college students in Guangdong province, China
Limited research exists on college students’ attitudes towards premarital sex in China, despite its increasing prevalence among youth. This study...
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Assessing the suitability of video-assisted anal fistula treatment for obese patients compared to conventional surgery: a question worth investigating
Background and aimsVideo-assisted anal fistula treatment (VAAFT) is an innovative surgical approach enabling the direct visualization of the fistula...
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Autoantibodies Neutralizing GM-CSF in HIV-Negative Colombian Patients Infected with Cryptococcus gattii and C. neoformans
BackgroundCryptococcosis is a life-threatening disease caused by Cryptococcus neoformans or C. gattii . Neutralizing autoantibodies (auto-Abs)...
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Association of cord blood Ang-1 and sCD105 levels with bronchopulmonary dysplasia in preterm infants
BackgroundTo investigate the relationship between cord blood levels of Angiopoietin-1 (Ang-1) and S-endoglin (sCD105) and bronchopulmonary dysplasia...
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I/O-efficient iterative matrix inversion with photonic integrated circuits
Photonic integrated circuits have been extensively explored for optical processing with the aim of breaking the speed and energy...
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Pharmacodynamic Comparison of Two Aspirin Formulations in the Caribbean: The ARC Study
IntroductionThis prospective, single-arm, crossover pharmacodynamic study assessed the effect of Bayer ® low-dose enteric-coated aspirin 81 mg...
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Die Psyche atmet mit
BackgroundIn addition to significant physical limitations, individuals with interstitial lung diseases (ILD) often experience reduced quality of life...
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Fractional order cancer model infection in human with CD8+ T cells and anti-PD-L1 therapy: simulations and control strategy
In order to comprehend the dynamics of disease propagation within a society, mathematical formulations are essential. The purpose of this work is to...
